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| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | PSMA7 | Proteasome subunit alpha type-7-like; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removi [...] (248 aa) |
| | BICRA | BRD4 interacting chromatin remodeling complex associated protein. (1542 aa) |
| | LOC102145093 | Ubiquitin-conjugating enzyme E2 C. (179 aa) |
| | UBE2C | Ubiquitin-conjugating enzyme E2 C; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | ENSMFAP00000012842 | Proteasome endopeptidase complex. (217 aa) |
| | ENSMFAP00000012290 | Ubiquitin-like domain-containing protein. (156 aa) |
| | ENSMFAP00000011989 | Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa) |
| | ENSMFAP00000011880 | Ubiquitin-like domain-containing protein. (128 aa) |
| | ENSMFAP00000011762 | ANK_REP_REGION domain-containing protein. (116 aa) |
| | PSMA8 | Proteasome endopeptidase complex. (132 aa) |
| | PSMB11 | Proteasome subunit beta. (300 aa) |
| | LOC101864869 | Ubiquitin-like domain-containing protein. (156 aa) |
| | CDC26 | Cell division cycle 26. (85 aa) |
| | UBC | Ubiquitin C. (645 aa) |
| | ENSMFAP00000010019 | ANK_REP_REGION domain-containing protein. (159 aa) |
| | RB1 | RB transcriptional corepressor 1. (928 aa) |
| | ENSMFAP00000009883 | Ubiquitin-like domain-containing protein. (147 aa) |
| | ENSMFAP00000009536 | Proteasome subunit alpha type. (236 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (755 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | ENSMFAP00000006175 | AAA domain-containing protein. (372 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | PSMB7 | Proteasome subunit beta. (302 aa) |
| | ENSMFAP00000005841 | Ubiquitin-like domain-containing protein. (122 aa) |
| | ENSMFAP00000005736 | Protein kinase domain-containing protein. (334 aa) |
| | ENSMFAP00000005693 | CSN8_PSD8_EIF3K domain-containing protein. (226 aa) |
| | CDC23 | Cell division cycle 23. (597 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | PSMD14 | 26S proteasome regulatory subunit N11. (310 aa) |
| | PSMA4 | Proteasome subunit alpha type-4; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (261 aa) |
| | ENSMFAP00000004537 | Prot_ATP_ID_OB domain-containing protein. (166 aa) |
| | AURKA | Aurora kinase A; Belongs to the protein kinase superfamily. (403 aa) |
| | CDC20 | WD_REPEATS_REGION domain-containing protein. (499 aa) |
| | ENSMFAP00000003583 | Uncharacterized protein. (379 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) |
| | ENSMFAP00000002424 | DOC domain-containing protein. (128 aa) |
| | ENSMFAP00000001997 | PROTEASOME_ALPHA_1 domain-containing protein. (45 aa) |
| | ENSMFAP00000001953 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (164 aa) |
| | ENSMFAP00000001720 | AAA domain-containing protein; Belongs to the AAA ATPase family. (384 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | FAM89A | Family with sequence similarity 89 member A. (184 aa) |
| | ANAPC16 | Anaphase promoting complex subunit 16. (110 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (403 aa) |
| | PSMC2 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] (433 aa) |
| | CDC16 | Cell division cycle 16. (526 aa) |
| | ENSMFAP00000027900 | ANK_REP_REGION domain-containing protein. (163 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | PSMB6 | Proteasome subunit beta. (250 aa) |
| | KXD1 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (232 aa) |
| | CDC27 | Cell division cycle 27. (830 aa) |
| | PSMC5 | 26S proteasome regulatory subunit T6; Belongs to the AAA ATPase family. (406 aa) |
| | ANAPC11 | Anaphase promoting complex subunit 11. (180 aa) |
| | FAM89B | Family with sequence similarity 89 member B. (154 aa) |
| | PSMA6 | Proteasome subunit alpha type. (252 aa) |
| | CDC20B | Cell division cycle 20B. (519 aa) |
| | ENSMFAP00000023218 | AAA domain-containing protein; Belongs to the AAA ATPase family. (366 aa) |
| | KIAA2012 | KIAA2012. (1180 aa) |
| | PSME1 | Proteasome activator complex subunit 1; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity). (249 aa) |
| | ENSMFAP00000021715 | Proteasome subunit alpha type. (174 aa) |
| | ENSMFAP00000021346 | Uncharacterized protein. (182 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PSMD12 | PCI domain-containing protein. (456 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | PSMD13 | PCI domain-containing protein. (399 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (334 aa) |
| | PTTG2 | Pituitary tumor-transforming 2. (169 aa) |
| | ENSMFAP00000015936 | Ubiquitin-like domain-containing protein. (144 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (599 aa) |
| | SKP2 | S-phase kinase associated protein 2. (424 aa) |
| | LOC102128144 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | AURKC | Aurora kinase C; Belongs to the protein kinase superfamily. (309 aa) |
| | LOC102117118 | Ubiquitin-like domain-containing protein. (127 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (681 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1944 aa) |
| | ENSMFAP00000042309 | Uncharacterized protein. (191 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (570 aa) |
| | UBB | Uncharacterized protein. (219 aa) |
| | PSME3 | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] (265 aa) |
| | ENSMFAP00000040007 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (168 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (603 aa) |
| | ENSMFAP00000039848 | MPN domain-containing protein. (149 aa) |
| | UBE2E1 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (176 aa) |
| | PTTG1 | PTTG1 regulator of sister chromatid separation, securin. (202 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (322 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (345 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa) |
| | ANAPC4 | Anaphase promoting complex subunit 4. (981 aa) |
| | RPS27A | Brain cDNA, clone: QccE-15346, similar to human ribosomal protein S27a (RPS27A). (156 aa) |
| | PSMC4 | 26S proteasome regulatory subunit 6B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated wit [...] (418 aa) |
| | ENSMFAP00000035194 | AAA domain-containing protein; Belongs to the AAA ATPase family. (418 aa) |
| | PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (451 aa) |
| | ENSMFAP00000034774 | Uncharacterized protein. (158 aa) |
| | PSME4 | Proteasome activator subunit 4. (1844 aa) |
| | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5 (By similarity). (508 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (496 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) |
| | ANAPC15 | Anaphase promoting complex subunit 15. (190 aa) |
| | PSMA1 | Proteasome subunit alpha type-1; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (269 aa) |
