STRINGSTRING
SLC2A1 SLC2A1 GPC1 GPC1 PANK1 PANK1 LRP3 LRP3 ENSMFAP00000018097 ENSMFAP00000018097 MMAA MMAA MTR MTR ENSMFAP00000018412 ENSMFAP00000018412 ENSMFAP00000019853 ENSMFAP00000019853 NT5E NT5E MINDY2 MINDY2 PTGIS PTGIS NMRK2 NMRK2 ST20-MTHFS ST20-MTHFS COQ2 COQ2 TTPA TTPA PTS PTS ENSMFAP00000021447 ENSMFAP00000021447 BCO1 BCO1 TPK1 TPK1 GPC5 GPC5 SLC22A13 SLC22A13 APOM APOM MTHFR MTHFR THTPA THTPA SLC52A1 SLC52A1 BST1 BST1 VNN2 VNN2 NAXE NAXE NMNAT2 NMNAT2 MACROD2 MACROD2 GPC3 GPC3 GSTO2 GSTO2 ENSMFAP00000025342 ENSMFAP00000025342 NMNAT3 NMNAT3 ENSMFAP00000025463 ENSMFAP00000025463 VNN1 VNN1 FAM162B FAM162B RFK RFK PANK2 PANK2 PC PC GPC6 GPC6 ENSMFAP00000026928 ENSMFAP00000026928 MTHFD2 MTHFD2 PARP10 PARP10 NFS1 NFS1 COQ9 COQ9 ENSMFAP00000027670 ENSMFAP00000027670 ENSMFAP00000027696 ENSMFAP00000027696 ACP5 ACP5 DHFR DHFR LRP2 LRP2 ACACA ACACA SLC25A43 SLC25A43 SLC52A3 SLC52A3 PYROXD2 PYROXD2 SLC25A47 SLC25A47 MROH6 MROH6 PTGS2 PTGS2 LRAT LRAT SLC46A3 SLC46A3 ENSMFAP00000014199 ENSMFAP00000014199 LOC102134776 LOC102134776 SLC25A19 SLC25A19 ENSMFAP00000014680 ENSMFAP00000014680 CDCP2 CDCP2 MOCS1 MOCS1 HSPG2 HSPG2 PARP9 PARP9 CUBN CUBN FPGS FPGS PPCDC PPCDC APOA2 APOA2 PDSS2 PDSS2 PANK3 PANK3 CYB5R3 CYB5R3 LRP8 LRP8 ABCD4 ABCD4 SLC5A8 SLC5A8 SDC4 SDC4 MTHFD1L MTHFD1L HLCS HLCS SLC5A6 SLC5A6 NAXD NAXD LOC102131386 LOC102131386 FAM162A FAM162A RBP1 RBP1 ALDH1L2 ALDH1L2 NNMT NNMT ENPP3 ENPP3 GPHN GPHN GSTO1 GSTO1 MTHFD2L MTHFD2L MCCC1 MCCC1 APOB APOB PPCS PPCS ENSMFAP00000002797 ENSMFAP00000002797 GPC4 GPC4 CD38 CD38 ENSMFAP00000003206 ENSMFAP00000003206 ZC3HAV1 ZC3HAV1 RETSAT RETSAT NMNAT1 NMNAT1 UBIAD1 UBIAD1 MMADHC MMADHC APOC3 APOC3 NOS3 NOS3 SLC25A16 SLC25A16 SHMT2 SHMT2 NMRK1 NMRK1 ENSMFAP00000005158 ENSMFAP00000005158 SLC23A1 SLC23A1 DCAKD DCAKD TTR TTR TIPARP TIPARP SDC3 SDC3 TTPAL TTPAL MMACHC MMACHC PLB1 PLB1 PARP16 PARP16 MMAB MMAB LRP10 LRP10 NADK NADK MCCC2 MCCC2 COQ7 COQ7 PANK4 PANK4 PCCB PCCB MACROD1 MACROD1 PARP4 PARP4 BTD BTD LRP12 LRP12 ENSMFAP00000010096 ENSMFAP00000010096 CD320 CD320 ENSMFAP00000011258 ENSMFAP00000011258 ITPRIPL2 ITPRIPL2 AIG1 AIG1 LOC102147021 LOC102147021 APOC2 APOC2 PCCA PCCA NEUROD6 NEUROD6 PARP15 PARP15 FLAD1 FLAD1 LMBRD1 LMBRD1 PARP6 PARP6 NAMPT NAMPT GCHFR GCHFR GCH1 GCH1 GPIHBP1 GPIHBP1 BCO2 BCO2 GPC2 GPC2 MINDY1 MINDY1 RBP2 RBP2 ABCC1 ABCC1 SLC46A1 SLC46A1 LRP1 LRP1 SLC25A32 SLC25A32 PNPO PNPO CYP8B1 CYP8B1 SLC23A2 SLC23A2 NAPRT NAPRT ZC3HAV1L ZC3HAV1L NADSYN1 NADSYN1 SLC19A2 SLC19A2 ENSMFAP00000042377 ENSMFAP00000042377 ALDH1L1 ALDH1L1 NADK2 NADK2 CBLIF CBLIF SPR SPR SLC19A1 SLC19A1 LPL LPL CCDC181 CCDC181 SDC2 SDC2 MMUT MMUT SDC1 SDC1 AASDHPPT AASDHPPT TCN2 TCN2 SLC52A2 SLC52A2 COQ6 COQ6 GDAP2 GDAP2 ENPP1 ENPP1 ADTRP ADTRP ENSMFAP00000038745 ENSMFAP00000038745 TCN1 TCN1 FASN FASN RDH11 RDH11 AGRN AGRN C12H2orf83 C12H2orf83 COQ5 COQ5 ENSMFAP00000037883 ENSMFAP00000037883 CCDC30 CCDC30 C1QTNF5 C1QTNF5 PARP14 PARP14 PRKG2 PRKG2 DHFR2 DHFR2 APOA1 APOA1 IDH1 IDH1 LOC102143754 LOC102143754 MOCS2 MOCS2 AKR1C8P AKR1C8P SLC22A14 SLC22A14 RNLS RNLS SHMT1 SHMT1 AOX2 AOX2 AKR1C1-2 AKR1C1-2 NUDT12 NUDT12 COQ3 COQ3 ENSMFAP00000035796 ENSMFAP00000035796 COASY COASY ENSMFAP00000034238 ENSMFAP00000034238 SLC19A3 SLC19A3 PARP8 PARP8 ENSMFAP00000033177 ENSMFAP00000033177 AOX4 AOX4 ENPP2 ENPP2 QPRT QPRT HSP90AA1 HSP90AA1 PDZD11 PDZD11 AOX1 AOX1 MTHFD1 MTHFD1 LRP1B LRP1B CTRB2 CTRB2 MTRR MTRR ENSMFAP00000031125 ENSMFAP00000031125 PDSS1 PDSS1 RBP4 RBP4 PDXK PDXK ANKRD16 ANKRD16 CLPS CLPS LDLR LDLR APOE APOE APOA4 APOA4 ACACB ACACB AKT1 AKT1 ENSMFAP00000017473 ENSMFAP00000017473 MOCOS MOCOS
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
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textmining
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protein homology
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SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
PANK1Pantothenate kinase 1. (598 aa)
LRP3LDL receptor related protein 3. (755 aa)
ENSMFAP00000018097CTP_transf_like domain-containing protein. (138 aa)
MMAAMetabolism of cobalamin associated A. (419 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1268 aa)
ENSMFAP00000018412HATPase_c domain-containing protein. (644 aa)
ENSMFAP00000019853Uncharacterized protein. (3228 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa)
MINDY2MINDY lysine 48 deubiquitinase 2. (621 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
NMRK2Nicotinamide riboside kinase 2. (221 aa)
ST20-MTHFS5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (229 aa)
COQ24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (420 aa)
TTPAAlpha tocopherol transfer protein. (278 aa)
PTS6-pyruvoyl tetrahydrobiopterin synthase. (145 aa)
ENSMFAP00000021447Uncharacterized protein. (146 aa)
BCO1Beta-carotene oxygenase 1. (454 aa)
TPK1Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (243 aa)
GPC5Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (572 aa)
SLC22A13Solute carrier family 22 member 13. (551 aa)
APOMApolipoprotein M. (188 aa)
MTHFRMethylenetetrahydrofolate reductase; Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. (697 aa)
THTPAThiamine-triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP). (230 aa)
SLC52A1Solute carrier family 52 member 1. (448 aa)
BST1ADP-ribosyl cyclase CD157. (315 aa)
VNN2Vanin 2. (520 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa)
NMNAT2Nicotinamide nucleotide adenylyltransferase 2. (307 aa)
MACROD2Mono-ADP ribosylhydrolase 2. (425 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa)
GSTO2Glutathione S-transferase omega 2; Belongs to the GST superfamily. (243 aa)
ENSMFAP00000025342Aldo_ket_red domain-containing protein. (313 aa)
NMNAT3Nicotinamide-nucleotide adenylyltransferase. (252 aa)
ENSMFAP00000025463Uncharacterized protein. (163 aa)
VNN1Vanin 1. (513 aa)
FAM162BFamily with sequence similarity 162 member B. (162 aa)
RFKFlavokinase domain-containing protein. (162 aa)
PANK2Pantothenate kinase 2. (567 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1179 aa)
GPC6Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (555 aa)
ENSMFAP00000026928Uncharacterized protein. (877 aa)
MTHFD2Uncharacterized protein. (222 aa)
PARP10Poly [ADP-ribose] polymerase. (1026 aa)
NFS1Aminotran_5 domain-containing protein. (615 aa)
COQ9Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (319 aa)
ENSMFAP00000027670Uncharacterized protein. (286 aa)
ENSMFAP00000027696DHFR domain-containing protein. (155 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
DHFRDHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
LRP2LDL receptor related protein 2. (4655 aa)
ACACAAcetyl-CoA carboxylase alpha. (2383 aa)
SLC25A43Solute carrier family 25 member 43; Belongs to the mitochondrial carrier (TC 2.A.29) family. (341 aa)
SLC52A3Solute carrier family 52 member 3. (469 aa)
PYROXD2Pyridine nucleotide-disulphide oxidoreductase domain 2. (581 aa)
SLC25A47Solute carrier family 25 member 47; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)
MROH6Maestro heat like repeat family member 6. (716 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
LRATLecithin retinol acyltransferase. (230 aa)
SLC46A3Solute carrier family 46 member 3. (461 aa)
ENSMFAP00000014199HATPase_c domain-containing protein. (307 aa)
LOC102134776Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (134 aa)
SLC25A19Mitochondrial thiamine pyrophosphate carrier; Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria. (309 aa)
ENSMFAP00000014680Uncharacterized protein. (287 aa)
CDCP2CUB domain containing protein 2. (540 aa)
MOCS1Molybdenum cofactor synthesis 1. (646 aa)
HSPG2Heparan sulfate proteoglycan 2. (4391 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (818 aa)
CUBNCubilin. (3624 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (580 aa)
PPCDCPhosphopantothenoylcysteine decarboxylase. (221 aa)
APOA2Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism; Belongs to the apolipoprotein A2 family. (132 aa)
PDSS2Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (399 aa)
PANK3Pantothenate kinase 3. (378 aa)
CYB5R3NADH-cytochrome b5 reductase 3 membrane-bound form; Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. (333 aa)
LRP8LDL receptor related protein 8. (971 aa)
ABCD4ATP binding cassette subfamily D member 4. (614 aa)
SLC5A8Solute carrier family 5 member 8; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (611 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (976 aa)
HLCSHolocarboxylase synthetase. (874 aa)
SLC5A6Solute carrier family 5 member 6; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (636 aa)
NAXDATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (391 aa)
LOC102131386VKc domain-containing protein. (155 aa)
FAM162AFamily with sequence similarity 162 member A. (155 aa)
RBP1Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (197 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
NNMTNicotinamide N-methyltransferase. (264 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (874 aa)
GPHNMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (782 aa)
GSTO1Glutathione S-transferase omega 1. (241 aa)
MTHFD2LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa)
MCCC1Methylcrotonoyl-CoA carboxylase 1. (731 aa)
APOBApolipoprotein B. (4555 aa)
PPCSPhosphopantothenoylcysteine synthetase. (311 aa)
ENSMFAP00000002797DHFR domain-containing protein. (175 aa)
GPC4Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
CD38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system (By similarity). (301 aa)
ENSMFAP00000003206Uncharacterized protein. (361 aa)
ZC3HAV1Zinc finger CCCH-type containing, antiviral 1. (1025 aa)
RETSATAll-trans-retinol 13,14-reductase; Catalyzes the saturation of all-trans-retinol to all-trans- 13,14-dihydroretinol. Does not exhibit any activity toward all-trans- retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A. Independently of retinol conversion, may regulate liver metabolism upstream of MLXIPL/ChREBP. May play a role in adipocyte differentiation. Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily. (610 aa)
NMNAT1Nicotinamide-nucleotide adenylyltransferase. (279 aa)
UBIAD1UbiA prenyltransferase domain containing 1. (338 aa)
MMADHCUncharacterized protein. (323 aa)
APOC3Apolipoprotein C-III; Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tigh [...] (99 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
SLC25A16Uncharacterized protein. (91 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
NMRK1Nicotinamide riboside kinase 1. (207 aa)
ENSMFAP00000005158Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (156 aa)
SLC23A1Solute carrier family 23 member 1. (516 aa)
DCAKDDephospho-CoA kinase domain containing. (135 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). (157 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (657 aa)
SDC3Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (422 aa)
TTPALCRAL-TRIO domain-containing protein. (342 aa)
MMACHCMetabolism of cobalamin associated C. (282 aa)
PLB1Phospholipase B1. (1461 aa)
PARP16Poly [ADP-ribose] polymerase. (477 aa)
MMABCorrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (244 aa)
LRP10LDL receptor related protein 10. (714 aa)
NADKNAD kinase. (586 aa)
MCCC2Methylcrotonoyl-CoA carboxylase 2. (563 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (219 aa)
PANK44'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their co [...] (781 aa)
PCCBUncharacterized protein. (570 aa)
MACROD1Mono-ADP ribosylhydrolase 1. (325 aa)
PARP4Uncharacterized protein. (311 aa)
BTDBiotinidase. (573 aa)
LRP12Low-density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor (By similarity). (859 aa)
ENSMFAP00000010096Uncharacterized protein; Belongs to the GST superfamily. (241 aa)
CD320CD320 molecule. (264 aa)
ENSMFAP00000011258Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (319 aa)
ITPRIPL2ITPRIP like 2. (535 aa)
AIG1Androgen induced 1. (245 aa)
LOC102147021Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (262 aa)
APOC2Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. Belongs to the apolipoprotein C2 family. (101 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (728 aa)
NEUROD6Neurogenic differentiation factor 6; Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its own gene (By similarity). (337 aa)
PARP15Poly [ADP-ribose] polymerase. (660 aa)
FLAD1FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. (562 aa)
LMBRD1Probable lysosomal cobalamin transporter; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity). (540 aa)
PARP6Poly [ADP-ribose] polymerase. (630 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
GCHFRGTP cyclohydrolase I feedback regulator. (84 aa)
GCH1GTP cyclohydrolase 1. (250 aa)
GPIHBP1Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (184 aa)
BCO2Beta,beta-carotene 9',10'-oxygenase; Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta- ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects (By similarity); Belongs to the carotenoid oxygenase family. (579 aa)
GPC2Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (578 aa)
MINDY1MINDY lysine 48 deubiquitinase 1. (514 aa)
RBP2Retinol binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
ABCC1Multidrug resistance-associated protein 1; Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (By similarity). Participates in [...] (1496 aa)
SLC46A1Solute carrier family 46 member 1. (460 aa)
LRP1LDL receptor related protein 1. (4544 aa)
SLC25A32Mitochondrial folate transporter/carrier; Transports folate across the inner membranes of mitochondria (By similarity). Can also transport FAD across the mitochondrial inner membrane (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
PNPOUncharacterized protein. (261 aa)
CYP8B1Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (496 aa)
SLC23A2Solute carrier family 23 member 2. (650 aa)
NAPRTNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (543 aa)
ZC3HAV1LZinc finger CCCH-type containing, antiviral 1 like. (300 aa)
NADSYN1Glutamine-dependent NAD(+) synthetase. (714 aa)
SLC19A2Solute carrier family 19 member 2. (495 aa)
ENSMFAP00000042377Uncharacterized protein. (251 aa)
ALDH1L110-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (914 aa)
NADK2NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. (442 aa)
CBLIFCobalamin binding intrinsic factor. (417 aa)
SPRSepiapterin reductase. (261 aa)
SLC19A1Solute carrier family 19 member 1. (584 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
CCDC181Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. (508 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
MMUTMethylmalonyl-CoA mutase, mitochondrial; Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle; Belongs to the methylmalonyl-CoA mutase family. (750 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
AASDHPPTAminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (310 aa)
TCN2Transcobalamin 2. (427 aa)
SLC52A2Solute carrier family 52 member 2. (444 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (468 aa)
GDAP2Ganglioside-induced differentiation-associated protein 2; Belongs to the GDAP2 family. (457 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (925 aa)
ADTRPAndrogen dependent TFPI regulating protein. (248 aa)
ENSMFAP00000038745Flavokinase domain-containing protein. (135 aa)
TCN1Transcobalamin 1. (434 aa)
FASNFatty acid synthase. (2502 aa)
RDH11Androgen-regulated short-chain dehydrogenase/reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
AGRNAgrin. (2044 aa)
C12H2orf83Uncharacterized protein. (109 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (327 aa)
ENSMFAP00000037883Dynein light chain. (119 aa)
CCDC30Coiled-coil domain-containing protein 30. (783 aa)
C1QTNF5C1q and TNF related 5. (243 aa)
PARP14Poly [ADP-ribose] polymerase. (1800 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
DHFR2Dihydrofolate reductase 2. (167 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. (267 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (417 aa)
LOC102143754Vitamin K epoxide reductase complex subunit 1 like 1. (176 aa)
MOCS2Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. (226 aa)
AKR1C8PAldo-keto reductase family 1 member C8, pseudogene. (325 aa)
SLC22A14MFS domain-containing protein. (610 aa)
RNLSRenalase, FAD dependent amine oxidase. (342 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa)
AOX2Aldehyde oxidase 2; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as phthalazine, as well as aldehydes, such as benzaldehyde and retinal. (1354 aa)
AKR1C1-2Aldo_ket_red domain-containing protein. (366 aa)
NUDT12Peroxisomal NADH pyrophosphatase NUDT12; Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle. (462 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (368 aa)
ENSMFAP00000035796DHFR domain-containing protein. (132 aa)
COASYCoenzyme A synthase. (564 aa)
ENSMFAP00000034238Flavokinase domain-containing protein. (156 aa)
SLC19A3Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity (By similarity). Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family. (496 aa)
PARP8Poly [ADP-ribose] polymerase. (894 aa)
ENSMFAP00000033177Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (430 aa)
AOX4Uncharacterized protein. (1322 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa)
QPRTNicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (305 aa)
HSP90AA1Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] (831 aa)
PDZD11PDZ domain-containing protein. (140 aa)
AOX1Aldehyde oxidase 1; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen specie [...] (1338 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (996 aa)
LRP1BLDL receptor related protein 1B. (4599 aa)
CTRB2Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (725 aa)
ENSMFAP00000031125Uncharacterized protein. (97 aa)
PDSS1Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (415 aa)
RBP4Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa)
PDXKPyridoxal kinase. (312 aa)
ANKRD16Ankyrin repeat domain 16. (361 aa)
CLPSColipase. (112 aa)
LDLRLow density lipoprotein receptor. (860 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
APOA4Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons; Belongs to the apolipoprotein A1/A4/E family. (441 aa)
ACACBAcetyl-CoA carboxylase beta. (2375 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ENSMFAP00000017473DHFR domain-containing protein. (138 aa)
MOCOSMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (891 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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