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| | SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa) |
| | GPC1 | Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa) |
| | PANK1 | Pantothenate kinase 1. (598 aa) |
| | LRP3 | LDL receptor related protein 3. (755 aa) |
| | ENSMFAP00000018097 | CTP_transf_like domain-containing protein. (138 aa) |
| | MMAA | Metabolism of cobalamin associated A. (419 aa) |
| | MTR | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1268 aa) |
| | ENSMFAP00000018412 | HATPase_c domain-containing protein. (644 aa) |
| | ENSMFAP00000019853 | Uncharacterized protein. (3228 aa) |
| | NT5E | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa) |
| | MINDY2 | MINDY lysine 48 deubiquitinase 2. (621 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | NMRK2 | Nicotinamide riboside kinase 2. (221 aa) |
| | ST20-MTHFS | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (229 aa) |
| | COQ2 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (420 aa) |
| | TTPA | Alpha tocopherol transfer protein. (278 aa) |
| | PTS | 6-pyruvoyl tetrahydrobiopterin synthase. (145 aa) |
| | ENSMFAP00000021447 | Uncharacterized protein. (146 aa) |
| | BCO1 | Beta-carotene oxygenase 1. (454 aa) |
| | TPK1 | Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (243 aa) |
| | GPC5 | Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (572 aa) |
| | SLC22A13 | Solute carrier family 22 member 13. (551 aa) |
| | APOM | Apolipoprotein M. (188 aa) |
| | MTHFR | Methylenetetrahydrofolate reductase; Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. (697 aa) |
| | THTPA | Thiamine-triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP). (230 aa) |
| | SLC52A1 | Solute carrier family 52 member 1. (448 aa) |
| | BST1 | ADP-ribosyl cyclase CD157. (315 aa) |
| | VNN2 | Vanin 2. (520 aa) |
| | NAXE | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa) |
| | NMNAT2 | Nicotinamide nucleotide adenylyltransferase 2. (307 aa) |
| | MACROD2 | Mono-ADP ribosylhydrolase 2. (425 aa) |
| | GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa) |
| | GSTO2 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. (243 aa) |
| | ENSMFAP00000025342 | Aldo_ket_red domain-containing protein. (313 aa) |
| | NMNAT3 | Nicotinamide-nucleotide adenylyltransferase. (252 aa) |
| | ENSMFAP00000025463 | Uncharacterized protein. (163 aa) |
| | VNN1 | Vanin 1. (513 aa) |
| | FAM162B | Family with sequence similarity 162 member B. (162 aa) |
| | RFK | Flavokinase domain-containing protein. (162 aa) |
| | PANK2 | Pantothenate kinase 2. (567 aa) |
| | PC | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1179 aa) |
| | GPC6 | Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (555 aa) |
| | ENSMFAP00000026928 | Uncharacterized protein. (877 aa) |
| | MTHFD2 | Uncharacterized protein. (222 aa) |
| | PARP10 | Poly [ADP-ribose] polymerase. (1026 aa) |
| | NFS1 | Aminotran_5 domain-containing protein. (615 aa) |
| | COQ9 | Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (319 aa) |
| | ENSMFAP00000027670 | Uncharacterized protein. (286 aa) |
| | ENSMFAP00000027696 | DHFR domain-containing protein. (155 aa) |
| | ACP5 | Tartrate-resistant acid phosphatase type 5. (325 aa) |
| | DHFR | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa) |
| | LRP2 | LDL receptor related protein 2. (4655 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2383 aa) |
| | SLC25A43 | Solute carrier family 25 member 43; Belongs to the mitochondrial carrier (TC 2.A.29) family. (341 aa) |
| | SLC52A3 | Solute carrier family 52 member 3. (469 aa) |
| | PYROXD2 | Pyridine nucleotide-disulphide oxidoreductase domain 2. (581 aa) |
| | SLC25A47 | Solute carrier family 25 member 47; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa) |
| | MROH6 | Maestro heat like repeat family member 6. (716 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | LRAT | Lecithin retinol acyltransferase. (230 aa) |
| | SLC46A3 | Solute carrier family 46 member 3. (461 aa) |
| | ENSMFAP00000014199 | HATPase_c domain-containing protein. (307 aa) |
| | LOC102134776 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (134 aa) |
| | SLC25A19 | Mitochondrial thiamine pyrophosphate carrier; Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria. (309 aa) |
| | ENSMFAP00000014680 | Uncharacterized protein. (287 aa) |
| | CDCP2 | CUB domain containing protein 2. (540 aa) |
| | MOCS1 | Molybdenum cofactor synthesis 1. (646 aa) |
| | HSPG2 | Heparan sulfate proteoglycan 2. (4391 aa) |
| | PARP9 | Poly(ADP-ribose) polymerase family member 9. (818 aa) |
| | CUBN | Cubilin. (3624 aa) |
| | FPGS | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (580 aa) |
| | PPCDC | Phosphopantothenoylcysteine decarboxylase. (221 aa) |
| | APOA2 | Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism; Belongs to the apolipoprotein A2 family. (132 aa) |
| | PDSS2 | Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (399 aa) |
| | PANK3 | Pantothenate kinase 3. (378 aa) |
| | CYB5R3 | NADH-cytochrome b5 reductase 3 membrane-bound form; Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. (333 aa) |
| | LRP8 | LDL receptor related protein 8. (971 aa) |
| | ABCD4 | ATP binding cassette subfamily D member 4. (614 aa) |
| | SLC5A8 | Solute carrier family 5 member 8; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (611 aa) |
| | SDC4 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa) |
| | MTHFD1L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (976 aa) |
| | HLCS | Holocarboxylase synthetase. (874 aa) |
| | SLC5A6 | Solute carrier family 5 member 6; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (636 aa) |
| | NAXD | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (391 aa) |
| | LOC102131386 | VKc domain-containing protein. (155 aa) |
| | FAM162A | Family with sequence similarity 162 member A. (155 aa) |
| | RBP1 | Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (197 aa) |
| | ALDH1L2 | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa) |
| | NNMT | Nicotinamide N-methyltransferase. (264 aa) |
| | ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. (874 aa) |
| | GPHN | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (782 aa) |
| | GSTO1 | Glutathione S-transferase omega 1. (241 aa) |
| | MTHFD2L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa) |
| | MCCC1 | Methylcrotonoyl-CoA carboxylase 1. (731 aa) |
| | APOB | Apolipoprotein B. (4555 aa) |
| | PPCS | Phosphopantothenoylcysteine synthetase. (311 aa) |
| | ENSMFAP00000002797 | DHFR domain-containing protein. (175 aa) |
| | GPC4 | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa) |
| | CD38 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system (By similarity). (301 aa) |
| | ENSMFAP00000003206 | Uncharacterized protein. (361 aa) |
| | ZC3HAV1 | Zinc finger CCCH-type containing, antiviral 1. (1025 aa) |
| | RETSAT | All-trans-retinol 13,14-reductase; Catalyzes the saturation of all-trans-retinol to all-trans- 13,14-dihydroretinol. Does not exhibit any activity toward all-trans- retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A. Independently of retinol conversion, may regulate liver metabolism upstream of MLXIPL/ChREBP. May play a role in adipocyte differentiation. Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily. (610 aa) |
| | NMNAT1 | Nicotinamide-nucleotide adenylyltransferase. (279 aa) |
| | UBIAD1 | UbiA prenyltransferase domain containing 1. (338 aa) |
| | MMADHC | Uncharacterized protein. (323 aa) |
| | APOC3 | Apolipoprotein C-III; Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tigh [...] (99 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) |
| | SLC25A16 | Uncharacterized protein. (91 aa) |
| | SHMT2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa) |
| | NMRK1 | Nicotinamide riboside kinase 1. (207 aa) |
| | ENSMFAP00000005158 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (156 aa) |
| | SLC23A1 | Solute carrier family 23 member 1. (516 aa) |
| | DCAKD | Dephospho-CoA kinase domain containing. (135 aa) |
| | TTR | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). (157 aa) |
| | TIPARP | TCDD inducible poly(ADP-ribose) polymerase. (657 aa) |
| | SDC3 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (422 aa) |
| | TTPAL | CRAL-TRIO domain-containing protein. (342 aa) |
| | MMACHC | Metabolism of cobalamin associated C. (282 aa) |
| | PLB1 | Phospholipase B1. (1461 aa) |
| | PARP16 | Poly [ADP-ribose] polymerase. (477 aa) |
| | MMAB | Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (244 aa) |
| | LRP10 | LDL receptor related protein 10. (714 aa) |
| | NADK | NAD kinase. (586 aa) |
| | MCCC2 | Methylcrotonoyl-CoA carboxylase 2. (563 aa) |
| | COQ7 | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (219 aa) |
| | PANK4 | 4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their co [...] (781 aa) |
| | PCCB | Uncharacterized protein. (570 aa) |
| | MACROD1 | Mono-ADP ribosylhydrolase 1. (325 aa) |
| | PARP4 | Uncharacterized protein. (311 aa) |
| | BTD | Biotinidase. (573 aa) |
| | LRP12 | Low-density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor (By similarity). (859 aa) |
| | ENSMFAP00000010096 | Uncharacterized protein; Belongs to the GST superfamily. (241 aa) |
| | CD320 | CD320 molecule. (264 aa) |
| | ENSMFAP00000011258 | Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (319 aa) |
| | ITPRIPL2 | ITPRIP like 2. (535 aa) |
| | AIG1 | Androgen induced 1. (245 aa) |
| | LOC102147021 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (262 aa) |
| | APOC2 | Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. Belongs to the apolipoprotein C2 family. (101 aa) |
| | PCCA | Propionyl-CoA carboxylase subunit alpha. (728 aa) |
| | NEUROD6 | Neurogenic differentiation factor 6; Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its own gene (By similarity). (337 aa) |
| | PARP15 | Poly [ADP-ribose] polymerase. (660 aa) |
| | FLAD1 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. (562 aa) |
| | LMBRD1 | Probable lysosomal cobalamin transporter; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity). (540 aa) |
| | PARP6 | Poly [ADP-ribose] polymerase. (630 aa) |
| | NAMPT | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa) |
| | GCHFR | GTP cyclohydrolase I feedback regulator. (84 aa) |
| | GCH1 | GTP cyclohydrolase 1. (250 aa) |
| | GPIHBP1 | Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (184 aa) |
| | BCO2 | Beta,beta-carotene 9',10'-oxygenase; Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta- ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects (By similarity); Belongs to the carotenoid oxygenase family. (579 aa) |
| | GPC2 | Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (578 aa) |
| | MINDY1 | MINDY lysine 48 deubiquitinase 1. (514 aa) |
| | RBP2 | Retinol binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa) |
| | ABCC1 | Multidrug resistance-associated protein 1; Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (By similarity). Participates in [...] (1496 aa) |
| | SLC46A1 | Solute carrier family 46 member 1. (460 aa) |
| | LRP1 | LDL receptor related protein 1. (4544 aa) |
| | SLC25A32 | Mitochondrial folate transporter/carrier; Transports folate across the inner membranes of mitochondria (By similarity). Can also transport FAD across the mitochondrial inner membrane (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa) |
| | PNPO | Uncharacterized protein. (261 aa) |
| | CYP8B1 | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (496 aa) |
| | SLC23A2 | Solute carrier family 23 member 2. (650 aa) |
| | NAPRT | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (543 aa) |
| | ZC3HAV1L | Zinc finger CCCH-type containing, antiviral 1 like. (300 aa) |
| | NADSYN1 | Glutamine-dependent NAD(+) synthetase. (714 aa) |
| | SLC19A2 | Solute carrier family 19 member 2. (495 aa) |
| | ENSMFAP00000042377 | Uncharacterized protein. (251 aa) |
| | ALDH1L1 | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (914 aa) |
| | NADK2 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. (442 aa) |
| | CBLIF | Cobalamin binding intrinsic factor. (417 aa) |
| | SPR | Sepiapterin reductase. (261 aa) |
| | SLC19A1 | Solute carrier family 19 member 1. (584 aa) |
| | LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa) |
| | CCDC181 | Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. (508 aa) |
| | SDC2 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa) |
| | MMUT | Methylmalonyl-CoA mutase, mitochondrial; Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle; Belongs to the methylmalonyl-CoA mutase family. (750 aa) |
| | SDC1 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa) |
| | AASDHPPT | Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (310 aa) |
| | TCN2 | Transcobalamin 2. (427 aa) |
| | SLC52A2 | Solute carrier family 52 member 2. (444 aa) |
| | COQ6 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (468 aa) |
| | GDAP2 | Ganglioside-induced differentiation-associated protein 2; Belongs to the GDAP2 family. (457 aa) |
| | ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (925 aa) |
| | ADTRP | Androgen dependent TFPI regulating protein. (248 aa) |
| | ENSMFAP00000038745 | Flavokinase domain-containing protein. (135 aa) |
| | TCN1 | Transcobalamin 1. (434 aa) |
| | FASN | Fatty acid synthase. (2502 aa) |
| | RDH11 | Androgen-regulated short-chain dehydrogenase/reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa) |
| | AGRN | Agrin. (2044 aa) |
| | C12H2orf83 | Uncharacterized protein. (109 aa) |
| | COQ5 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (327 aa) |
| | ENSMFAP00000037883 | Dynein light chain. (119 aa) |
| | CCDC30 | Coiled-coil domain-containing protein 30. (783 aa) |
| | C1QTNF5 | C1q and TNF related 5. (243 aa) |
| | PARP14 | Poly [ADP-ribose] polymerase. (1800 aa) |
| | PRKG2 | cGMP-dependent protein kinase. (762 aa) |
| | DHFR2 | Dihydrofolate reductase 2. (167 aa) |
| | APOA1 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. (267 aa) |
| | IDH1 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (417 aa) |
| | LOC102143754 | Vitamin K epoxide reductase complex subunit 1 like 1. (176 aa) |
| | MOCS2 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. (226 aa) |
| | AKR1C8P | Aldo-keto reductase family 1 member C8, pseudogene. (325 aa) |
| | SLC22A14 | MFS domain-containing protein. (610 aa) |
| | RNLS | Renalase, FAD dependent amine oxidase. (342 aa) |
| | SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa) |
| | AOX2 | Aldehyde oxidase 2; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as phthalazine, as well as aldehydes, such as benzaldehyde and retinal. (1354 aa) |
| | AKR1C1-2 | Aldo_ket_red domain-containing protein. (366 aa) |
| | NUDT12 | Peroxisomal NADH pyrophosphatase NUDT12; Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle. (462 aa) |
| | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (368 aa) |
| | ENSMFAP00000035796 | DHFR domain-containing protein. (132 aa) |
| | COASY | Coenzyme A synthase. (564 aa) |
| | ENSMFAP00000034238 | Flavokinase domain-containing protein. (156 aa) |
| | SLC19A3 | Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity (By similarity). Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family. (496 aa) |
| | PARP8 | Poly [ADP-ribose] polymerase. (894 aa) |
| | ENSMFAP00000033177 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (430 aa) |
| | AOX4 | Uncharacterized protein. (1322 aa) |
| | ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa) |
| | QPRT | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (305 aa) |
| | HSP90AA1 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] (831 aa) |
| | PDZD11 | PDZ domain-containing protein. (140 aa) |
| | AOX1 | Aldehyde oxidase 1; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen specie [...] (1338 aa) |
| | MTHFD1 | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (996 aa) |
| | LRP1B | LDL receptor related protein 1B. (4599 aa) |
| | CTRB2 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa) |
| | MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (725 aa) |
| | ENSMFAP00000031125 | Uncharacterized protein. (97 aa) |
| | PDSS1 | Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (415 aa) |
| | RBP4 | Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa) |
| | PDXK | Pyridoxal kinase. (312 aa) |
| | ANKRD16 | Ankyrin repeat domain 16. (361 aa) |
| | CLPS | Colipase. (112 aa) |
| | LDLR | Low density lipoprotein receptor. (860 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) |
| | APOA4 | Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons; Belongs to the apolipoprotein A1/A4/E family. (441 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2375 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | ENSMFAP00000017473 | DHFR domain-containing protein. (138 aa) |
| | MOCOS | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (891 aa) |
