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| | ENSMFAP00000010764 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | TFRC | Transferrin receptor. (760 aa) |
| | RAB5C | RAB5C, member RAS oncogene family. (249 aa) |
| | CLHC1 | Clathrin heavy chain linker domain-containing protein 1. (586 aa) |
| | AP1S3 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (164 aa) |
| | CLTC | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa) |
| | AP1B1 | AP complex subunit beta. (949 aa) |
| | TPD52L1 | Uncharacterized protein. (221 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1063 aa) |
| | TBC1D8B | TBC1 domain family member 8B. (1107 aa) |
| | HCLS1 | SH3 domain-containing protein. (475 aa) |
| | DNASE2B | Uncharacterized protein. (361 aa) |
| | ENSMFAP00000042269 | Uncharacterized protein. (147 aa) |
| | SNAP23 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa) |
| | SNX5 | Sorting nexin; Involved in several stages of intracellular trafficking. (405 aa) |
| | HIP1R | Huntingtin interacting protein 1 related. (1068 aa) |
| | DNM2 | Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa) |
| | TBC1D9 | TBC1 domain family member 9. (1266 aa) |
| | HSPA8 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa) |
| | AP1G2 | AP-1 complex subunit gamma. (785 aa) |
| | SPAG5 | Sperm associated antigen 5. (1195 aa) |
| | AP1G1 | AP-1 complex subunit gamma. (817 aa) |
| | FTL | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (175 aa) |
| | VAMP8 | Vesicle associated membrane protein 8. (100 aa) |
| | TPD52L3 | TPD52 like 3. (135 aa) |
| | IGF2R | Insulin like growth factor 2 receptor. (2491 aa) |
| | PICALM | Phosphatidylinositol binding clathrin assembly protein. (686 aa) |
| | TBC1D8 | TBC1 domain family member 8. (1155 aa) |
| | SNX32 | Sorting nexin; Involved in several stages of intracellular trafficking. (403 aa) |
| | DNASE2 | Uncharacterized protein. (360 aa) |
| | AP3S1 | Adaptor related protein complex 3 subunit sigma 1. (193 aa) |
| | CLVS2 | Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). (327 aa) |
| | M6PR | Mannose-6-phosphate receptor, cation dependent. (278 aa) |
| | RSPH9 | Radial spoke head 9 homolog. (301 aa) |
| | MTSS2 | MTSS I-BAR domain containing 2. (748 aa) |
| | SNX6 | Sorting nexin 6. (358 aa) |
| | AP4E1 | AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. (1098 aa) |
| | CLINT1 | Clathrin interactor 1. (643 aa) |
| | AP1S2 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa) |
| | CLTB | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa) |
| | LOC102114955 | MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (72 aa) |
| | AP3B2 | AP-3 complex subunit beta. (1101 aa) |
| | CHMP2A | Charged multivesicular body protein 2A. (222 aa) |
| | BLOC1S6 | Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (172 aa) |
| | SORCS2 | Sortilin related VPS10 domain containing receptor 2. (1119 aa) |
| | PIK3C2A | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1666 aa) |
| | AP4M1 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (453 aa) |
| | APP | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (770 aa) |
| | YIPF6 | Protein YIPF. (236 aa) |
| | CTSZ | Cathepsin Z; Belongs to the peptidase C1 family. (368 aa) |
| | SBSN | Suprabasin. (536 aa) |
| | LOC102136620 | Uncharacterized protein. (64 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (830 aa) |
| | BLOC1S4 | Uncharacterized protein. (216 aa) |
| | ENSMFAP00000011572 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | BLOC1S3 | Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (200 aa) |
| | AP4B1 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa) |
| | PUM1 | Pumilio RNA binding family member 1. (1195 aa) |
| | SNX2 | Sorting nexin-2; Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called en [...] (519 aa) |
| | ENSMFAP00000014202 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (571 aa) |
| | AP1S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa) |
| | VAMP7 | Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa) |
| | GOLGB1 | Golgin B1. (3268 aa) |
| | TPD52 | Uncharacterized protein. (274 aa) |
| | VAMP2 | V-SNARE coiled-coil homology domain-containing protein. (118 aa) |
| | ENSMFAP00000016806 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (107 aa) |
| | NECAP1 | DUF1681 domain-containing protein. (275 aa) |
| | ENSMFAP00000017524 | Uncharacterized protein. (189 aa) |
| | TBRG4 | Transforming growth factor beta regulator 4. (631 aa) |
| | SH3D19 | SH3 domain containing 19. (1046 aa) |
| | AP4S1 | Adaptor related protein complex 4 subunit sigma 1. (158 aa) |
| | TPD52L2 | Uncharacterized protein. (156 aa) |
| | OCRL | OCRL inositol polyphosphate-5-phosphatase. (901 aa) |
| | CLVS1 | CRAL-TRIO domain-containing protein. (354 aa) |
| | ENSMFAP00000021941 | Uncharacterized protein. (362 aa) |
| | AP1M1 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (435 aa) |
| | SULF2 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (951 aa) |
| | ENSMFAP00000022812 | Uncharacterized protein. (421 aa) |
| | ZFYVE19 | Zinc finger FYVE-type containing 19. (470 aa) |
| | GAK | Cyclin G associated kinase. (1311 aa) |
| | SULF1 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa) |
| | SORT1 | Sortilin. (831 aa) |
| | SH3GL2 | SH3 domain containing GRB2 like 2, endophilin A1. (341 aa) |
| | SORCS3 | Sortilin related VPS10 domain containing receptor 3. (1222 aa) |
| | DNAJC6 | DnaJ heat shock protein family (Hsp40) member C6. (970 aa) |
| | STX4 | Syntaxin 4; Belongs to the syntaxin family. (171 aa) |
| | CLTA | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa) |
| | ARPIN | Clat_adaptor_s domain-containing protein. (394 aa) |
| | ENSMFAP00000028626 | Uncharacterized protein. (154 aa) |
| | ACBD3 | Acyl-CoA binding domain containing 3. (528 aa) |
| | ARF1 | ADP-ribosylation factor 1; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs p [...] (181 aa) |
| | AP5M1 | AP-5 complex subunit mu-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. (490 aa) |
| | SNX1 | Sorting nexin-1; Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called en [...] (557 aa) |
| | ZFYVE1 | Zinc finger FYVE-type containing 1. (796 aa) |
| | GNS | Glucosamine (N-acetyl)-6-sulfatase. (584 aa) |
| | ENSMFAP00000000762 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (578 aa) |
| | TBC1D9B | TBC1 domain family member 9B. (1268 aa) |
| | MTSS1 | MTSS I-BAR domain containing 1. (795 aa) |
| | CPD | Carboxypeptidase D. (1378 aa) |
| | DTNBP1 | Dystrobrevin binding protein 1. (350 aa) |
| | ARRB1 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] (473 aa) |
| | SORCS1 | Sortilin related VPS10 domain containing receptor 1. (1168 aa) |
| | SNX9 | Sorting nexin. (596 aa) |
| | TXNDC5 | Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (431 aa) |
| | TGOLN2 | Trans-golgi network protein 2. (417 aa) |
| | GBF1 | Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1859 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | ENSMFAP00000033337 | PX domain-containing protein. (206 aa) |
| | NAPA | Alpha-soluble NSF attachment protein. (295 aa) |
