Your Input: | |
| | CD101 | CD101 molecule. (1021 aa) |
| | CD247 | Uncharacterized protein. (168 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | ENSMFAP00000005841 | Ubiquitin-like domain-containing protein. (122 aa) |
| | ENSMFAP00000005693 | CSN8_PSD8_EIF3K domain-containing protein. (226 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | PSMD14 | 26S proteasome regulatory subunit N11. (310 aa) |
| | PSMA4 | Proteasome subunit alpha type-4; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (261 aa) |
| | TRAT1 | T cell receptor associated transmembrane adaptor 1. (187 aa) |
| | ENSMFAP00000004537 | Prot_ATP_ID_OB domain-containing protein. (166 aa) |
| | SPNS1 | Sphingolipid transporter 1 (putative). (573 aa) |
| | ENSMFAP00000003583 | Uncharacterized protein. (379 aa) |
| | LOC102140782 | Ig-like domain-containing protein. (325 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (233 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] (198 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | LAT | Linker for activation of T cells. (270 aa) |
| | ENSMFAP00000001720 | AAA domain-containing protein; Belongs to the AAA ATPase family. (384 aa) |
| | HLA-DPA1 | Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa) |
| | PSMA7 | Proteasome subunit alpha type-7-like; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removi [...] (248 aa) |
| | ITK | Tyrosine-protein kinase. (620 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (403 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | TRAC | Macaca fascicularis brain cDNA, clone: QflA-22619. (110 aa) |
| | UBE2N | Ubiquitin-conjugating enzyme E2 N; The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Acts together with the E3 ligases, HLTF and SHPRH, in the 'Lys-63'-linked poly- ubiquitination of [...] (152 aa) |
| | LCP2 | Lymphocyte cytosolic protein 2. (533 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (167 aa) |
| | PAK3 | P21 (RAC1) activated kinase 3. (580 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (542 aa) |
| | CD3G | T-cell surface glycoprotein CD3 gamma chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] (181 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | ENSMFAP00000042495 | Ig-like domain-containing protein. (133 aa) |
| | ENSMFAP00000042309 | Uncharacterized protein. (191 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa) |
| | UBB | Uncharacterized protein. (219 aa) |
| | PSME3 | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] (265 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | ENSMFAP00000039848 | MPN domain-containing protein. (149 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | FYB1 | FYN binding protein 1. (839 aa) |
| | CSK | Tyrosine-protein kinase. (450 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (322 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | ZAP70 | Tyrosine-protein kinase. (619 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa) |
| | RPS27A | Brain cDNA, clone: QccE-15346, similar to human ribosomal protein S27a (RPS27A). (156 aa) |
| | PSMC4 | 26S proteasome regulatory subunit 6B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated wit [...] (418 aa) |
| | PIK3R2 | Uncharacterized protein. (694 aa) |
| | ENSMFAP00000035194 | AAA domain-containing protein; Belongs to the AAA ATPase family. (418 aa) |
| | PTPRJ | Protein tyrosine phosphatase receptor type J. (1279 aa) |
| | PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (451 aa) |
| | ENSMFAP00000034774 | Uncharacterized protein. (158 aa) |
| | PSME4 | Proteasome activator subunit 4. (1844 aa) |
| | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5 (By similarity). (508 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (545 aa) |
| | CDC34 | Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (194 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | PSMA1 | Proteasome subunit alpha type-1; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (269 aa) |
| | VASP | Vasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (378 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1127 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | HLA-DPB1 | Major histocompatibility complex, class II, DP beta 1. (264 aa) |
| | ENSMFAP00000031351 | Uncharacterized protein; Belongs to the SKP1 family. (166 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | PSMC2 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] (433 aa) |
| | MALT1 | MALT1 paracaspase. (824 aa) |
| | ENSMFAP00000030335 | Uncharacterized protein; Belongs to the SKP1 family. (141 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (813 aa) |
| | CD3D | T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] (171 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | ENSMFAP00000027900 | ANK_REP_REGION domain-containing protein. (163 aa) |
| | GRAP2 | GRB2 related adaptor protein 2. (330 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | PSMB6 | Proteasome subunit beta. (250 aa) |
| | KXD1 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (232 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) |
| | HLA-DRB1 | Major histocompatibility complex, class II, DR beta 1. (249 aa) |
| | PSMC5 | 26S proteasome regulatory subunit T6; Belongs to the AAA ATPase family. (406 aa) |
| | PSMA6 | Proteasome subunit alpha type. (252 aa) |
| | ENSMFAP00000023218 | AAA domain-containing protein; Belongs to the AAA ATPase family. (366 aa) |
| | PSME1 | Proteasome activator complex subunit 1; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity). (249 aa) |
| | ENSMFAP00000021715 | Proteasome subunit alpha type. (174 aa) |
| | PAG1 | Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (432 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (544 aa) |
| | ENSMFAP00000019905 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (141 aa) |
| | INPP5D | Inositol polyphosphate-5-phosphatase D. (978 aa) |
| | PSMD12 | PCI domain-containing protein. (456 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | PSMD13 | PCI domain-containing protein. (399 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (334 aa) |
| | HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) |
| | LCK | Tyrosine-protein kinase. (342 aa) |
| | ENSMFAP00000015936 | Ubiquitin-like domain-containing protein. (144 aa) |
| | ENSMFAP00000015310 | Uncharacterized protein. (304 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (510 aa) |
| | UBE2NL | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | ENSMFAP00000014022 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (152 aa) |
| | SPNS3 | Sphingolipid transporter 3 (putative). (426 aa) |
| | LOC102117118 | Ubiquitin-like domain-containing protein. (127 aa) |
| | ENSMFAP00000013287 | TNF receptor-associated factor. (474 aa) |
| | LOC102136325 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (152 aa) |
| | ENSMFAP00000012842 | Proteasome endopeptidase complex. (217 aa) |
| | ENSMFAP00000012290 | Ubiquitin-like domain-containing protein. (156 aa) |
| | ENAH | ENAH actin regulator. (790 aa) |
| | ENSMFAP00000011989 | Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | ENSMFAP00000011880 | Ubiquitin-like domain-containing protein. (128 aa) |
| | ENSMFAP00000011762 | ANK_REP_REGION domain-containing protein. (116 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (317 aa) |
| | PSMA8 | Proteasome endopeptidase complex. (132 aa) |
| | PSMB11 | Proteasome subunit beta. (300 aa) |
| | LOC102124821 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (128 aa) |
| | LOC101864869 | Ubiquitin-like domain-containing protein. (156 aa) |
| | UBC | Ubiquitin C. (645 aa) |
| | BTRC | Uncharacterized protein. (605 aa) |
| | HLA-DQB2 | Major histocompatibility complex, class II, DQ beta 1. (242 aa) |
| | DQB1 | Ig-like domain-containing protein. (156 aa) |
| | ENSMFAP00000010019 | ANK_REP_REGION domain-containing protein. (159 aa) |
| | ENSMFAP00000009883 | Ubiquitin-like domain-containing protein. (147 aa) |
| | ENSMFAP00000009791 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa) |
| | ENSMFAP00000009536 | Proteasome subunit alpha type. (236 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (800 aa) |
| | EVL | WH1 domain-containing protein. (456 aa) |
| | HLA-DRB5 | Ig-like domain-containing protein. (286 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1072 aa) |
| | WAS | WASP actin nucleation promoting factor. (503 aa) |
| | ENSMFAP00000006175 | AAA domain-containing protein. (372 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | PSMB7 | Proteasome subunit beta. (302 aa) |
