STRINGSTRING
SNW1 SNW1 PPM1A PPM1A SMAD3 SMAD3 MAPK1 MAPK1 NCOR2 NCOR2 PARP1 PARP1 ENSMFAP00000005841 ENSMFAP00000005841 TGIF2LY TGIF2LY SMURF2 SMURF2 TGIF2 TGIF2 HDAC1 HDAC1 ENSMFAP00000009883 ENSMFAP00000009883 ENSMFAP00000010148 ENSMFAP00000010148 UBC UBC LOC101864869 LOC101864869 ENSMFAP00000011880 ENSMFAP00000011880 ENSMFAP00000012290 ENSMFAP00000012290 LOC102117118 LOC102117118 SKIL SKIL ENSMFAP00000015936 ENSMFAP00000015936 RNF111 RNF111 ENSMFAP00000016148 ENSMFAP00000016148 WWTR1 WWTR1 USP9X USP9X NEDD4L NEDD4L SKI SKI SMAD7 SMAD7 ENSMFAP00000025317 ENSMFAP00000025317 KXD1 KXD1 UBE2D1 UBE2D1 SMAD2 SMAD2 MAPK3 MAPK3 SMAD4 SMAD4 STAT1 STAT1 TGIF1 TGIF1 NCOR1 NCOR1 RPS27A RPS27A UBB UBB TRIM33 TRIM33 ATP1B4 ATP1B4 ENSMFAP00000043974 ENSMFAP00000043974 ENSMFAP00000045669 ENSMFAP00000045669
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNW1SNW domain containing 1. (571 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
NCOR2Nuclear receptor corepressor 2. (2510 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
ENSMFAP00000005841Ubiquitin-like domain-containing protein. (122 aa)
TGIF2LYHomeobox protein TGIF2LX; May have a transcription role in testis; Belongs to the TALE/TGIF homeobox family. (177 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
ENSMFAP00000009883Ubiquitin-like domain-containing protein. (147 aa)
ENSMFAP00000010148Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (421 aa)
UBCUbiquitin C. (645 aa)
LOC101864869Ubiquitin-like domain-containing protein. (156 aa)
ENSMFAP00000011880Ubiquitin-like domain-containing protein. (128 aa)
ENSMFAP00000012290Ubiquitin-like domain-containing protein. (156 aa)
LOC102117118Ubiquitin-like domain-containing protein. (127 aa)
SKILSKI like proto-oncogene. (684 aa)
ENSMFAP00000015936Ubiquitin-like domain-containing protein. (144 aa)
RNF111Ring finger protein 111. (1002 aa)
ENSMFAP00000016148PPM-type phosphatase domain-containing protein. (280 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2584 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1258 aa)
SKISKI proto-oncogene. (681 aa)
SMAD7Mothers against decapentaplegic homolog. (495 aa)
ENSMFAP00000025317Hist_deacetyl domain-containing protein. (258 aa)
KXD1Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (232 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
TGIF1TGFB induced factor homeobox 1. (312 aa)
NCOR1Nuclear receptor corepressor 1. (2442 aa)
RPS27ABrain cDNA, clone: QccE-15346, similar to human ribosomal protein S27a (RPS27A). (156 aa)
UBBUncharacterized protein. (219 aa)
TRIM33Tripartite motif containing 33. (1127 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
ENSMFAP00000043974Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (462 aa)
ENSMFAP00000045669SKIP_SNW domain-containing protein. (467 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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