42 items (Macaca fascicularis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	SNW1	SNW domain containing 1. (571 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	NCOR2	Nuclear receptor corepressor 2. (2510 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	ENSMFAP00000005841	Ubiquitin-like domain-containing protein. (122 aa)
	TGIF2LY	Homeobox protein TGIF2LX; May have a transcription role in testis; Belongs to the TALE/TGIF homeobox family. (177 aa)
	SMURF2	E3 ubiquitin-protein ligase. (748 aa)
	TGIF2	TGFB induced factor homeobox 2. (237 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	ENSMFAP00000009883	Ubiquitin-like domain-containing protein. (147 aa)
	ENSMFAP00000010148	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (421 aa)
	UBC	Ubiquitin C. (645 aa)
	LOC101864869	Ubiquitin-like domain-containing protein. (156 aa)
	ENSMFAP00000011880	Ubiquitin-like domain-containing protein. (128 aa)
	ENSMFAP00000012290	Ubiquitin-like domain-containing protein. (156 aa)
	LOC102117118	Ubiquitin-like domain-containing protein. (127 aa)
	SKIL	SKI like proto-oncogene. (684 aa)
	ENSMFAP00000015936	Ubiquitin-like domain-containing protein. (144 aa)
	RNF111	Ring finger protein 111. (1002 aa)
	ENSMFAP00000016148	PPM-type phosphatase domain-containing protein. (280 aa)
	WWTR1	WW domain containing transcription regulator 1. (400 aa)
	USP9X	Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2584 aa)
	NEDD4L	NEDD4 like E3 ubiquitin protein ligase. (1258 aa)
	SKI	SKI proto-oncogene. (681 aa)
	SMAD7	Mothers against decapentaplegic homolog. (495 aa)
	ENSMFAP00000025317	Hist_deacetyl domain-containing protein. (258 aa)
	KXD1	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (232 aa)
	UBE2D1	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	MAPK3	Mitogen-activated protein kinase. (322 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	STAT1	Signal transducer and activator of transcription. (758 aa)
	TGIF1	TGFB induced factor homeobox 1. (312 aa)
	NCOR1	Nuclear receptor corepressor 1. (2442 aa)
	RPS27A	Brain cDNA, clone: QccE-15346, similar to human ribosomal protein S27a (RPS27A). (156 aa)
	UBB	Uncharacterized protein. (219 aa)
	TRIM33	Tripartite motif containing 33. (1127 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
	ENSMFAP00000043974	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (462 aa)
	ENSMFAP00000045669	SKIP_SNW domain-containing protein. (467 aa)

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1B4	ENSMFAP00000045669	ENSMFAP00000042689	ENSMFAP00000045669	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SKIP_SNW domain-containing protein.	0.695
ATP1B4	MAPK1	ENSMFAP00000042689	ENSMFAP00000004712	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.900
ATP1B4	MAPK3	ENSMFAP00000042689	ENSMFAP00000029630	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mitogen-activated protein kinase.	0.900
ATP1B4	SNW1	ENSMFAP00000042689	ENSMFAP00000001078	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SNW domain containing 1.	0.695
ENSMFAP00000005841	ENSMFAP00000009883	ENSMFAP00000005841	ENSMFAP00000009883	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.861
ENSMFAP00000005841	ENSMFAP00000012290	ENSMFAP00000005841	ENSMFAP00000012290	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.860
ENSMFAP00000005841	ENSMFAP00000015936	ENSMFAP00000005841	ENSMFAP00000015936	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.847
ENSMFAP00000005841	LOC101864869	ENSMFAP00000005841	ENSMFAP00000010587	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.859
ENSMFAP00000005841	NEDD4L	ENSMFAP00000005841	ENSMFAP00000018222	Ubiquitin-like domain-containing protein.	NEDD4 like E3 ubiquitin protein ligase.	0.670
ENSMFAP00000005841	RNF111	ENSMFAP00000005841	ENSMFAP00000016084	Ubiquitin-like domain-containing protein.	Ring finger protein 111.	0.562
ENSMFAP00000005841	RPS27A	ENSMFAP00000005841	ENSMFAP00000037357	Ubiquitin-like domain-containing protein.	Brain cDNA, clone: QccE-15346, similar to human ribosomal protein S27a (RPS27A).	0.859
ENSMFAP00000005841	SMURF2	ENSMFAP00000005841	ENSMFAP00000006829	Ubiquitin-like domain-containing protein.	E3 ubiquitin-protein ligase.	0.737
ENSMFAP00000005841	UBB	ENSMFAP00000005841	ENSMFAP00000040895	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.815
ENSMFAP00000005841	UBC	ENSMFAP00000005841	ENSMFAP00000010479	Ubiquitin-like domain-containing protein.	Ubiquitin C.	0.811
ENSMFAP00000005841	UBE2D1	ENSMFAP00000005841	ENSMFAP00000027372	Ubiquitin-like domain-containing protein.	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.	0.677
ENSMFAP00000005841	WWTR1	ENSMFAP00000005841	ENSMFAP00000017293	Ubiquitin-like domain-containing protein.	WW domain containing transcription regulator 1.	0.425
ENSMFAP00000009883	ENSMFAP00000005841	ENSMFAP00000009883	ENSMFAP00000005841	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.861
ENSMFAP00000009883	ENSMFAP00000011880	ENSMFAP00000009883	ENSMFAP00000011880	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.875
ENSMFAP00000009883	KXD1	ENSMFAP00000009883	ENSMFAP00000027128	Ubiquitin-like domain-containing protein.	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]	0.918
ENSMFAP00000009883	LOC102117118	ENSMFAP00000009883	ENSMFAP00000013676	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.862

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