STRINGSTRING
ENSMFAP00000043974 ENSMFAP00000043974 ENSMFAP00000043809 ENSMFAP00000043809 MYC MYC TFDP2 TFDP2 UBB UBB RPS27A RPS27A ENSMFAP00000037272 ENSMFAP00000037272 CDK9 CDK9 TGIF1 TGIF1 CDK8 CDK8 SMAD4 SMAD4 CCNT1 CCNT1 MAPK3 MAPK3 SMAD2 SMAD2 COL1A2 COL1A2 SP1 SP1 KXD1 KXD1 TFDP3 TFDP3 ENSMFAP00000015144 ENSMFAP00000015144 RBL1 RBL1 LOC102117118 LOC102117118 ENSMFAP00000013160 ENSMFAP00000013160 ENSMFAP00000012290 ENSMFAP00000012290 ENSMFAP00000011880 ENSMFAP00000011880 ENSMFAP00000011451 ENSMFAP00000011451 LOC101864869 LOC101864869 JUNB JUNB UBC UBC ENSMFAP00000010148 ENSMFAP00000010148 ENSMFAP00000009883 ENSMFAP00000009883 HDAC1 HDAC1 TGIF2 TGIF2 FURIN FURIN CCNQ CCNQ ENSMFAP00000025317 ENSMFAP00000025317 ENSMFAP00000023399 ENSMFAP00000023399 MAPK1 MAPK1 SMAD3 SMAD3 E2F4 E2F4 YBX1 YBX1 CCNT2 CCNT2 SMAD7 SMAD7 TFDP1 TFDP1 WWTR1 WWTR1 CCNK CCNK RNF111 RNF111 ENSMFAP00000015936 ENSMFAP00000015936 CCNC CCNC ENSMFAP00000005841 ENSMFAP00000005841 MEN1 MEN1 PCSK4 PCSK4 EP300 EP300 SERPINE1 SERPINE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMFAP00000043974Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (462 aa)
ENSMFAP00000043809Uncharacterized protein. (125 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
TFDP2Transcription factor. (447 aa)
UBBUncharacterized protein. (219 aa)
RPS27ABrain cDNA, clone: QccE-15346, similar to human ribosomal protein S27a (RPS27A). (156 aa)
ENSMFAP00000037272Uncharacterized protein. (92 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
TGIF1TGFB induced factor homeobox 1. (312 aa)
CDK8Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
SP1Sp1 transcription factor. (786 aa)
KXD1Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (232 aa)
TFDP3Transcription factor. (406 aa)
ENSMFAP00000015144Uncharacterized protein. (97 aa)
RBL1RB transcriptional corepressor like 1. (1067 aa)
LOC102117118Ubiquitin-like domain-containing protein. (127 aa)
ENSMFAP00000013160CYCLIN domain-containing protein; Belongs to the cyclin family. (258 aa)
ENSMFAP00000012290Ubiquitin-like domain-containing protein. (156 aa)
ENSMFAP00000011880Ubiquitin-like domain-containing protein. (128 aa)
ENSMFAP00000011451Uncharacterized protein. (144 aa)
LOC101864869Ubiquitin-like domain-containing protein. (156 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
UBCUbiquitin C. (645 aa)
ENSMFAP00000010148Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (421 aa)
ENSMFAP00000009883Ubiquitin-like domain-containing protein. (147 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
CCNQCyclin Q; Belongs to the cyclin family. (248 aa)
ENSMFAP00000025317Hist_deacetyl domain-containing protein. (258 aa)
ENSMFAP00000023399Uncharacterized protein. (88 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
E2F4E2F transcription factor 4. (416 aa)
YBX1Y-box binding protein 1. (324 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (760 aa)
SMAD7Mothers against decapentaplegic homolog. (495 aa)
TFDP1Transcription factor. (410 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
CCNKCyclin K; Belongs to the cyclin family. (596 aa)
RNF111Ring finger protein 111. (1002 aa)
ENSMFAP00000015936Ubiquitin-like domain-containing protein. (144 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
ENSMFAP00000005841Ubiquitin-like domain-containing protein. (122 aa)
MEN1Menin 1. (615 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (758 aa)
EP300E1A binding protein p300. (2414 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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