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| | NUP37 | Nucleoporin 37. (326 aa) |
| | MAPRE2 | Microtubule associated protein RP/EB family member 2. (327 aa) |
| | CENPT | Centromere protein T; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3- containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and [...] (561 aa) |
| | CENPK | Centromere protein K. (269 aa) |
| | ZWILCH | Zwilch kinetochore protein. (591 aa) |
| | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa) |
| | CCNB2 | G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition. (398 aa) |
| | SKA1 | Spindle and kinetochore associated complex subunit 1. (255 aa) |
| | TUBB2A | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (420 aa) |
| | AHCTF1 | AT-hook containing transcription factor 1. (2274 aa) |
| | TUBB3 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (507 aa) |
| | DYNC1I1 | WD_REPEATS_REGION domain-containing protein. (645 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A regulatory subunit A. (589 aa) |
| | CENPQ | Centromere protein Q; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores. (160 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa) |
| | CDC20 | WD_REPEATS_REGION domain-containing protein. (499 aa) |
| | CLASP2 | Uncharacterized protein. (1514 aa) |
| | CDCA8 | Cell division cycle associated 8. (280 aa) |
| | CENPP | Centromere protein P. (288 aa) |
| | ENSMFAP00000004499 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (414 aa) |
| | CKAP5 | Cytoskeleton associated protein 5. (2032 aa) |
| | WDR41 | Uncharacterized protein. (475 aa) |
| | KIF18A | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (897 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa) |
| | ZWINT | ZW10 interacting kinetochore protein. (277 aa) |
| | RCC2 | Regulator of chromosome condensation 2. (523 aa) |
| | ENSMFAP00000007055 | Dynein light chain. (79 aa) |
| | BIRC5 | Uncharacterized protein. (209 aa) |
| | RPS27 | 40S ribosomal protein S27. (84 aa) |
| | TAOK1 | TAO kinase 1. (1001 aa) |
| | SKA2 | Spindle and kinetochore-associated protein 2; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a [...] (114 aa) |
| | TUBA3E | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | KIF2A | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa) |
| | NDC80 | Kinetochore protein NDC80 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spind [...] (642 aa) |
| | NDE1 | NUDE_C domain-containing protein. (377 aa) |
| | MAPRE3 | Microtubule associated protein RP/EB family member 3. (281 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | CENPE | Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2701 aa) |
| | CDK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa) |
| | ITGB3BP | Integrin subunit beta 3 binding protein. (216 aa) |
| | TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | CCNB1 | Cyclin B1. (356 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | LOC102125518 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (450 aa) |
| | DYNC1I2 | Dynein cytoplasmic 1 intermediate chain 2. (638 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (603 aa) |
| | MAD1L1 | Mitotic arrest deficient 1 like 1. (718 aa) |
| | CENPA | Centromere protein A. (138 aa) |
| | XPO1 | Exportin 1. (1071 aa) |
| | CENPF | Centromere protein F. (3113 aa) |
| | TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | NDEL1 | Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripe [...] (345 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (345 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa) |
| | LOC102121218 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa) |
| | ENSMFAP00000036892 | Uncharacterized protein. (105 aa) |
| | ENSMFAP00000036851 | Uncharacterized protein. (284 aa) |
| | STAG1 | Stromal antigen 1. (1258 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa) |
| | PDS5B | PDS5 cohesin associated factor B. (1448 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1233 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | TUBB | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) |
| | DSN1 | DSN1 component of MIS12 kinetochore complex. (354 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1217 aa) |
| | ENSMFAP00000033672 | CS domain-containing protein. (195 aa) |
| | HDAC8 | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (377 aa) |
| | ENSMFAP00000033392 | WD_REPEATS_REGION domain-containing protein. (275 aa) |
| | CENPH | Centromere protein H. (247 aa) |
| | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase. (1091 aa) |
| | CENPI | Centromere protein I. (756 aa) |
| | SEC13 | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa) |
| | WAPL | WAPL cohesin release factor. (1190 aa) |
| | RANGAP1 | Ran GTPase activating protein 1. (639 aa) |
| | TUBA1A | Detyrosinated tubulin alpha-1B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | CENPM | Centromere protein M. (180 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | NSL1 | NSL1 component of MIS12 kinetochore complex. (281 aa) |
| | ENSMFAP00000030009 | CS domain-containing protein. (326 aa) |
| | ENSMFAP00000029658 | Tubulin domain-containing protein. (92 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa) |
| | NUP85 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa) |
| | SGO2 | Shugoshin 2. (1258 aa) |
| | ENSMFAP00000028999 | Tubulin domain-containing protein. (126 aa) |
| | DYNC1LI2 | Cytoplasmic dynein 1 light intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes (By similarity). (492 aa) |
| | ENSMFAP00000028463 | Uncharacterized protein. (195 aa) |
| | CENPL | Centromere protein L. (390 aa) |
| | KNTC1 | Kinetochore associated 1. (2192 aa) |
| | ERCC6L | ERCC excision repair 6 like, spindle assembly checkpoint helicase. (1252 aa) |
| | DYNLL2 | Dynein light chain. (89 aa) |
| | KNL1 | Kinetochore scaffold 1. (2323 aa) |
| | NUP98 | Nucleoporin 98. (1610 aa) |
| | CDCA5 | Cell division cycle associated 5. (252 aa) |
| | BUB3 | BUB3, mitotic checkpoint protein. (328 aa) |
| | CNTD2 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (304 aa) |
| | NUP133 | Nucleoporin 133. (1156 aa) |
| | TUBB2B | Tubulin beta-2A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Belongs to the tubulin family. (445 aa) |
| | CLIP1 | CAP-Gly domain containing linker protein 1. (1438 aa) |
| | MAD2L1 | Mitotic spindle assembly checkpoint protein MAD2. (205 aa) |
| | KIF2C | Kinesin-like protein KIF2C; In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome- microtubule attachment; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily. (729 aa) |
| | CLASP1 | Cytoplasmic linker associated protein 1. (1533 aa) |
| | LOC102123543 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | CDC20B | Cell division cycle 20B. (519 aa) |
| | CENPU | Centromere protein U. (419 aa) |
| | PDS5A | PDS5 cohesin associated factor A. (1337 aa) |
| | ERCC6L2 | Uncharacterized protein. (1413 aa) |
| | DYNC1H1 | Dynein cytoplasmic 1 heavy chain 1. (4624 aa) |
| | TUBE1 | Tubulin epsilon 1; Belongs to the tubulin family. (475 aa) |
| | LOC102129286 | Tubulin domain-containing protein. (139 aa) |
| | TCERG1L | Transcription elongation regulator 1 like. (473 aa) |
| | NUP43 | WD_REPEATS_REGION domain-containing protein. (380 aa) |
| | ENSMFAP00000021904 | Dynein light chain. (83 aa) |
| | TUBA1C | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (484 aa) |
| | CCNB3 | Cyclin B3; Belongs to the cyclin family. (1363 aa) |
| | NUDC | Uncharacterized protein. (227 aa) |
| | SPC25 | SPC25 component of NDC80 kinetochore complex. (224 aa) |
| | ENSMFAP00000020443 | Rad21_Rec8 domain-containing protein. (521 aa) |
| | ENSMFAP00000020427 | Uncharacterized protein. (1151 aa) |
| | ENSMFAP00000019922 | Tubulin domain-containing protein. (158 aa) |
| | ENSMFAP00000019425 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (443 aa) |
| | RAD21 | RAD21 cohesin complex component. (631 aa) |
| | TUBB4A | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (359 aa) |
| | NUP107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa) |
| | CENPN | Centromere protein N. (345 aa) |
| | RAD21L1 | RAD21 cohesin complex component like 1. (556 aa) |
| | MTUS2 | Microtubule associated scaffold protein 2. (1383 aa) |
| | BUB1B | BUB1 N-terminal domain-containing protein. (1050 aa) |
| | NUP160 | Nucleoporin 160. (1436 aa) |
| | INCENP | Inner centromere protein. (897 aa) |
| | CENPO | Centromere protein O. (299 aa) |
| | DYNC1LI1 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (466 aa) |
| | ENSMFAP00000016524 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (436 aa) |
| | LOC102121175 | Uncharacterized protein. (325 aa) |
| | B9D2 | B9 domain containing 2. (175 aa) |
| | DYNLL1 | Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1. (89 aa) |
| | STAG2 | Stromal antigen 2. (1268 aa) |
| | MEIOC | Meiosis specific with coiled-coil domain. (955 aa) |
| | SPC24 | SPC24 component of NDC80 kinetochore complex. (197 aa) |
| | RANBP2 | RAN binding protein 2. (3221 aa) |
| | CLIP2 | CAP-Gly domain containing linker protein 2. (1046 aa) |
| | AURKC | Aurora kinase C; Belongs to the protein kinase superfamily. (309 aa) |
| | LOC102144746 | 40S ribosomal protein S27. (84 aa) |
| | BIRC5-2 | Uncharacterized protein. (142 aa) |
| | ENSMFAP00000014068 | Uncharacterized protein. (107 aa) |
| | ENSMFAP00000013926 | Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (363 aa) |
| | LOC102119942 | Uncharacterized protein. (84 aa) |
| | ENSMFAP00000013834 | HORMA domain-containing protein. (205 aa) |
| | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (414 aa) |
| | ENSMFAP00000013200 | 40S ribosomal protein S27. (84 aa) |
| | ENSMFAP00000013032 | annotation not available (84 aa) |
| | SPDL1 | Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Acts as an adapter protein linking the dynein motor complex to various [...] (622 aa) |
| | LOC102121435 | 40S ribosomal protein S27. (84 aa) |
| | MIS12 | Uncharacterized protein. (205 aa) |
| | ENSMFAP00000012561 | HORMA domain-containing protein. (205 aa) |
| | TUBB4B | Tubulin beta-4A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa) |
| | LOC102142638 | Protein kinase domain-containing protein. (297 aa) |
| | CENPC | Centromere protein C. (945 aa) |
| | ENSMFAP00000011155 | Uncharacterized protein. (84 aa) |
| | NUF2 | NUF2 component of NDC80 kinetochore complex. (464 aa) |
| | TUBA4A | Tubulin alpha-4A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. (448 aa) |
| | ENSMFAP00000010749 | Uncharacterized protein. (84 aa) |
| | ENSMFAP00000010659 | WD_REPEATS_REGION domain-containing protein. (377 aa) |
| | MAPRE1 | Uncharacterized protein. (268 aa) |
| | ZW10 | Zw10 kinetochore protein. (778 aa) |
| | SEH1L | SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (360 aa) |
| | SGO1 | Shugoshin 1. (527 aa) |
