STRINGSTRING
CTNNBIP1 CTNNBIP1 ZBTB44 ZBTB44 SOX5 SOX5 SOX8 SOX8 YWHAZ YWHAZ ASH2L ASH2L ENSMFAP00000005841 ENSMFAP00000005841 MEN1 MEN1 CTBP1 CTBP1 TLE2 TLE2 CTNNB1 CTNNB1 CHD8 CHD8 HDAC1 HDAC1 SOX12 SOX12 ENSMFAP00000009883 ENSMFAP00000009883 ENSMFAP00000010148 ENSMFAP00000010148 BTRC BTRC UBC UBC LOC101864869 LOC101864869 SOX1 SOX1 ENSMFAP00000011880 ENSMFAP00000011880 SOX11 SOX11 ENSMFAP00000012290 ENSMFAP00000012290 SOX6 SOX6 SOX2 SOX2 SOX14 SOX14 LOC102117118 LOC102117118 SOX30 SOX30 SOX15 SOX15 BTBD18 BTBD18 TLE7 TLE7 ENSMFAP00000015936 ENSMFAP00000015936 SOX3 SOX3 SOX4 SOX4 ENSMFAP00000016647 ENSMFAP00000016647 AKT1 AKT1 TLE4 TLE4 SOX13 SOX13 PYGO1 PYGO1 TCF7L1 TCF7L1 TCF7L2 TCF7L2 SOX17 SOX17 ENSMFAP00000025317 ENSMFAP00000025317 SOX7 SOX7 SOX21 SOX21 KXD1 KXD1 TCF7 TCF7 HMGXB4 HMGXB4 CBY1 CBY1 TLE1 TLE1 SOX18 SOX18 LEF1 LEF1 APC2 APC2 AKT2 AKT2 TLE6 TLE6 TLE3 TLE3 ENSMFAP00000035756 ENSMFAP00000035756 RPS27A RPS27A BHMG1 BHMG1 KMT2D KMT2D XPO1 XPO1 RBBP5 RBBP5 UBB UBB APC APC ENSMFAP00000041691 ENSMFAP00000041691 XIAP XIAP ENSMFAP00000043974 ENSMFAP00000043974 SOX9 SOX9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
ZBTB44Zinc finger and BTB domain containing 44. (570 aa)
SOX5SRY-box transcription factor 5. (763 aa)
SOX8HMG box domain-containing protein. (141 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (257 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (616 aa)
ENSMFAP00000005841Ubiquitin-like domain-containing protein. (122 aa)
MEN1Menin 1. (615 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (438 aa)
TLE2TLE family member 2, transcriptional corepressor. (736 aa)
CTNNB1Catenin beta 1. (781 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2589 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
SOX12SRY-box transcription factor 12. (238 aa)
ENSMFAP00000009883Ubiquitin-like domain-containing protein. (147 aa)
ENSMFAP00000010148Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (421 aa)
BTRCUncharacterized protein. (605 aa)
UBCUbiquitin C. (645 aa)
LOC101864869Ubiquitin-like domain-containing protein. (156 aa)
SOX1SRY-box transcription factor 1. (235 aa)
ENSMFAP00000011880Ubiquitin-like domain-containing protein. (128 aa)
SOX11Transcription factor SOX. (441 aa)
ENSMFAP00000012290Ubiquitin-like domain-containing protein. (156 aa)
SOX6SRY-box transcription factor 6. (828 aa)
SOX2SRY-box transcription factor 2. (319 aa)
SOX14Transcription factor SOX-14; Acts as a negative regulator of transcription. (240 aa)
LOC102117118Ubiquitin-like domain-containing protein. (127 aa)
SOX30Transcription factor SOX-30; Acts as both a transcriptional activator and repressor (By similarity). Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif (By similarity). Binds to its own promoter and activates its own transcription (By similarity). Required to activate the expression of postmeiotic genes involved in spermiogenesis (By similarity). Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling (By similarity). Also inhibits Wnt signaling by binding to the CTNNB1 [...] (753 aa)
SOX15SRY-box transcription factor 15. (233 aa)
BTBD18BTB domain containing 18. (713 aa)
TLE7TLE family member 7. (441 aa)
ENSMFAP00000015936Ubiquitin-like domain-containing protein. (144 aa)
SOX3SRY-box transcription factor 3. (446 aa)
SOX4Transcription factor SOX. (474 aa)
ENSMFAP00000016647Uncharacterized protein. (107 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
TLE4TLE family member 4, transcriptional corepressor. (805 aa)
SOX13SRY-box transcription factor 13. (621 aa)
PYGO1Pygopus family PHD finger 1. (419 aa)
TCF7L1Transcription factor 7 like 1. (589 aa)
TCF7L2Transcription factor 7 like 2. (542 aa)
SOX17Uncharacterized protein. (416 aa)
ENSMFAP00000025317Hist_deacetyl domain-containing protein. (258 aa)
SOX7SRY-box transcription factor 7. (388 aa)
SOX21SRY-box transcription factor 21. (222 aa)
KXD1Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (232 aa)
TCF7Transcription factor 7. (398 aa)
HMGXB4HMG-box containing 4. (644 aa)
CBY1Uncharacterized protein. (169 aa)
TLE1TLE family member 1, transcriptional corepressor. (770 aa)
SOX18SRY-box transcription factor 18. (325 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
APC2APC regulator of WNT signaling pathway 2. (2301 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
TLE6TLE family member 6, subcortical maternal complex member. (572 aa)
TLE3TLE family member 3, transcriptional corepressor. (782 aa)
ENSMFAP00000035756Uncharacterized protein. (197 aa)
RPS27ABrain cDNA, clone: QccE-15346, similar to human ribosomal protein S27a (RPS27A). (156 aa)
BHMG1Basic helix-loop-helix and HMG-box containing 1. (636 aa)
KMT2DLysine methyltransferase 2D. (5538 aa)
XPO1Exportin 1. (1071 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (548 aa)
UBBUncharacterized protein. (219 aa)
APCAPC regulator of WNT signaling pathway. (2861 aa)
ENSMFAP0000004169114_3_3 domain-containing protein; Belongs to the 14-3-3 family. (224 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
ENSMFAP00000043974Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (462 aa)
SOX9SRY-box transcription factor 9. (509 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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