STRINGSTRING
ATF4 ATF4 ENSMFAP00000000347 ENSMFAP00000000347 NFYB NFYB CALR CALR NFYC NFYC XBP1 XBP1 ATF6B ATF6B MBTPS1 MBTPS1 DDIT3 DDIT3 MBTPS2 MBTPS2 HSP90B1 HSP90B1 ENSMFAP00000032601 ENSMFAP00000032601 ATF6 ATF6 NFYA NFYA ENSMFAP00000041402 ENSMFAP00000041402 HSPA5 HSPA5 ENSMFAP00000043889 ENSMFAP00000043889
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATF4Activating transcription factor 4. (351 aa)
ENSMFAP00000000347CBFD_NFYB_HMF domain-containing protein. (200 aa)
NFYBCBFD_NFYB_HMF domain-containing protein. (208 aa)
CALRCalreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis. (417 aa)
NFYCNuclear transcription factor Y subunit gamma. (439 aa)
XBP1BZIP domain-containing protein. (380 aa)
ATF6BActivating transcription factor 6 beta. (708 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1054 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (520 aa)
HSP90B1Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family. (804 aa)
ENSMFAP00000032601CBFD_NFYB_HMF domain-containing protein. (287 aa)
ATF6Activating transcription factor 6. (669 aa)
NFYANuclear transcription factor Y subunit alpha. (347 aa)
ENSMFAP00000041402Uncharacterized protein. (155 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
ENSMFAP00000043889Uncharacterized protein; Belongs to the heat shock protein 70 family. (619 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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