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| | ABCC12 | ATP binding cassette subfamily C member 12. (1359 aa) |
| | LOC102132274 | Tr-type G domain-containing protein. (430 aa) |
| | DELE1 | DAP3 binding cell death enhancer 1. (522 aa) |
| | ENSMFAP00000042309 | Uncharacterized protein. (191 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | ABCA12 | ATP binding cassette subfamily A member 12. (2595 aa) |
| | PEX3 | Peroxisomal biogenesis factor 3; Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes (By similarity). (373 aa) |
| | ABCB7 | ATP binding cassette subfamily B member 7. (799 aa) |
| | UBB | Uncharacterized protein. (219 aa) |
| | ABCA8 | ATP binding cassette subfamily A member 8. (1621 aa) |
| | PSME3 | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] (265 aa) |
| | ENSMFAP00000039848 | MPN domain-containing protein. (149 aa) |
| | ABCG4 | ATP binding cassette subfamily G member 4. (646 aa) |
| | ABCB1 | Multidrug resistance p-glycoprotein. (1283 aa) |
| | ABCC2 | Multidrug resistance protein MRP2. (1545 aa) |
| | SPATA5L1 | Spermatogenesis associated 5 like 1. (771 aa) |
| | ABCG5 | ATP binding cassette subfamily G member 5. (651 aa) |
| | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5 (By similarity). (508 aa) |
| | PSME4 | Proteasome activator subunit 4. (1844 aa) |
| | ABCA6 | ATP binding cassette subfamily A member 6. (1618 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (322 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | ABCC5 | ATP binding cassette subfamily C member 5. (1437 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa) |
| | RPS27A | Brain cDNA, clone: QccE-15346, similar to human ribosomal protein S27a (RPS27A). (156 aa) |
| | ENSMFAP00000037120 | Tr-type G domain-containing protein. (366 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | SEL1L2 | SEL1L2 adaptor subunit of ERAD E3 ligase. (687 aa) |
| | PSMC4 | 26S proteasome regulatory subunit 6B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated wit [...] (418 aa) |
| | ENSMFAP00000034774 | Uncharacterized protein. (158 aa) |
| | PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (451 aa) |
| | ENSMFAP00000035194 | AAA domain-containing protein; Belongs to the AAA ATPase family. (418 aa) |
| | ENSMFAP00000035364 | Uncharacterized protein. (430 aa) |
| | ABCB8 | ATP binding cassette subfamily B member 8. (735 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | ABCG1 | ATP binding cassette subfamily G member 1. (690 aa) |
| | ENSMFAP00000001720 | AAA domain-containing protein; Belongs to the AAA ATPase family. (384 aa) |
| | ABCC10 | ATP binding cassette subfamily C member 10. (1476 aa) |
| | PTCHD1 | Patched domain containing 1. (888 aa) |
| | SEL1L | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (870 aa) |
| | ABCA9 | ATP binding cassette subfamily A member 9. (1624 aa) |
| | PTCHD3 | Patched domain containing 3. (769 aa) |
| | OS9 | OS9 endoplasmic reticulum lectin. (716 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) |
| | ABCC6 | ATP binding cassette subfamily C member 6. (1394 aa) |
| | ENSMFAP00000003583 | Uncharacterized protein. (379 aa) |
| | ENSMFAP00000004537 | Prot_ATP_ID_OB domain-containing protein. (166 aa) |
| | ABCD2 | ATP binding cassette subfamily D member 2. (720 aa) |
| | PSMA4 | Proteasome subunit alpha type-4; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (261 aa) |
| | SEL1L3 | SEL1L family member 3. (1121 aa) |
| | PSMD14 | 26S proteasome regulatory subunit N11. (310 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | ENSMFAP00000005693 | CSN8_PSD8_EIF3K domain-containing protein. (226 aa) |
| | ABCB9 | ATP binding cassette subfamily B member 9. (766 aa) |
| | ENSMFAP00000005841 | Ubiquitin-like domain-containing protein. (122 aa) |
| | PSMB7 | Proteasome subunit beta. (302 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | ENSMFAP00000006175 | AAA domain-containing protein. (372 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | ENSMFAP00000006481 | eIF2B_5 domain-containing protein. (287 aa) |
| | ABCC3 | ATP binding cassette subfamily C member 3. (1527 aa) |
| | ENSMFAP00000006837 | Uncharacterized protein. (1296 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1484 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | ABCA2 | ATP binding cassette subfamily A member 2. (2469 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | DERL3 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (238 aa) |
| | ABCF1 | ATP binding cassette subfamily F member 1. (948 aa) |
| | PLEKHD1 | Pleckstrin homology and coiled-coil domain containing D1. (506 aa) |
| | ENSMFAP00000009536 | Proteasome subunit alpha type. (236 aa) |
| | ENSMFAP00000009883 | Ubiquitin-like domain-containing protein. (147 aa) |
| | ENSMFAP00000010019 | ANK_REP_REGION domain-containing protein. (159 aa) |
| | UBC | Ubiquitin C. (645 aa) |
| | LOC101864869 | Ubiquitin-like domain-containing protein. (156 aa) |
| | PSMB11 | Proteasome subunit beta. (300 aa) |
| | KCNJ11 | Potassium voltage-gated channel subfamily J member 11. (390 aa) |
| | PSMA8 | Proteasome endopeptidase complex. (132 aa) |
| | ENSMFAP00000011762 | ANK_REP_REGION domain-containing protein. (116 aa) |
| | ENSMFAP00000011880 | Ubiquitin-like domain-containing protein. (128 aa) |
| | ENSMFAP00000011989 | Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa) |
| | ABCB5 | ATP binding cassette subfamily B member 5. (1257 aa) |
| | ENSMFAP00000012290 | Ubiquitin-like domain-containing protein. (156 aa) |
| | ENSMFAP00000012842 | Proteasome endopeptidase complex. (217 aa) |
| | LOC102117118 | Ubiquitin-like domain-containing protein. (127 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) |
| | ERLIN2 | ER lipid raft associated 2. (370 aa) |
| | ABCC11 | ATP binding cassette subfamily C member 11. (1382 aa) |
| | ENSMFAP00000015936 | Ubiquitin-like domain-containing protein. (144 aa) |
| | EIF2S3 | Tr-type G domain-containing protein. (472 aa) |
| | ABCA4 | Uncharacterized protein. (2282 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (334 aa) |
| | PSMD13 | PCI domain-containing protein. (399 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | ERLEC1 | Endoplasmic reticulum lectin 1. (483 aa) |
| | PSMD12 | PCI domain-containing protein. (456 aa) |
| | RNF5 | Ring finger protein 5. (180 aa) |
| | ABCA3 | ATP binding cassette subfamily A member 3. (1704 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | ENSMFAP00000021715 | Proteasome subunit alpha type. (174 aa) |
| | ENSMFAP00000021728 | eIF2B_5 domain-containing protein. (282 aa) |
| | ENSMFAP00000021872 | Uncharacterized protein. (203 aa) |
| | PSME1 | Proteasome activator complex subunit 1; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity). (249 aa) |
| | SPATA5 | Spermatogenesis associated 5. (892 aa) |
| | ENSMFAP00000023218 | AAA domain-containing protein; Belongs to the AAA ATPase family. (366 aa) |
| | SMPDL3A | Acid sphingomyelinase-like phosphodiesterase. (453 aa) |
| | ENSMFAP00000024195 | ABC transporter domain-containing protein. (194 aa) |
| | PSMA6 | Proteasome subunit alpha type. (252 aa) |
| | ENSMFAP00000024771 | ABC transporter domain-containing protein. (602 aa) |
| | PSMC5 | 26S proteasome regulatory subunit T6; Belongs to the AAA ATPase family. (406 aa) |
| | ABCD3 | ATP binding cassette subfamily D member 3. (659 aa) |
| | ABCB6 | ATP binding cassette subfamily B member 6 (Langereis blood group). (843 aa) |
| | DERL1 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (745 aa) |
| | KXD1 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (232 aa) |
| | PSMB6 | Proteasome subunit beta. (250 aa) |
| | ENSMFAP00000027900 | ANK_REP_REGION domain-containing protein. (163 aa) |
| | ABCG8 | ATP binding cassette subfamily G member 8. (673 aa) |
| | PEX19 | Peroxisomal biogenesis factor 19. (299 aa) |
| | ERLIN1 | ER lipid raft associated 1. (348 aa) |
| | ABCA5 | ATP binding cassette subfamily A member 5. (1646 aa) |
| | ABCC9 | ATP binding cassette subfamily C member 9. (1549 aa) |
| | DERL2 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa) |
| | PSMC2 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] (433 aa) |
| | ABCC4 | ATP binding cassette subfamily C member 4. (1325 aa) |
| | RNF185 | Ring finger protein 185. (192 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | PSMA1 | Proteasome subunit alpha type-1; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (269 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | EIF2S2 | Eukaryotic translation initiation factor 2 subunit beta. (333 aa) |
| | ABCB10 | ATP binding cassette subfamily B member 10. (738 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | LRP2BP | LRP2-binding protein; May act as an adapter that regulates LRP2 function. (348 aa) |
| | ABCA7 | ATP binding cassette subfamily A member 7. (2148 aa) |
| | ABCA10 | ATP binding cassette subfamily A member 10. (1523 aa) |
| | ENSMFAP00000035793 | Tr-type G domain-containing protein. (411 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | PTCHD4 | Patched domain containing 4. (846 aa) |
| | PSMA7 | Proteasome subunit alpha type-7-like; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removi [...] (248 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (403 aa) |
| | ABCF3 | ATP binding cassette subfamily F member 3. (709 aa) |
| | ENSMFAP00000045139 | eIF2B_5 domain-containing protein. (271 aa) |
| | ABCC1 | Multidrug resistance-associated protein 1; Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (By similarity). Participates in [...] (1496 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
