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MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa) | ||||
NR0B1 | Nuclear receptor subfamily 0 group B member 1. (470 aa) | ||||
HNF4G | Hepatocyte nuclear factor 4 gamma. (455 aa) | ||||
HNF4A | Hepatocyte nuclear factor 4 alpha. (474 aa) | ||||
ENSMFAP00000021707 | Nuclear receptor domain-containing protein. (255 aa) | ||||
ESRRA | Estrogen related receptor alpha. (422 aa) | ||||
NR2E3 | Nuclear receptor subfamily 2 group E member 3. (462 aa) | ||||
RORA | RAR related orphan receptor A. (555 aa) | ||||
NR5A1 | Nuclear receptor subfamily 5 group A member 1. (461 aa) | ||||
NR2F6 | Nuclear receptor subfamily 2 group F member 6. (404 aa) | ||||
RXRA | Retinoid X receptor alpha. (443 aa) | ||||
NR1I3 | Nuclear receptor subfamily 1 group I member 3. (357 aa) | ||||
NR2C2 | Nuclear receptor subfamily 2 group C member 2. (619 aa) | ||||
NR4A1 | Nuclear receptor subfamily 4 group A member 1. (670 aa) | ||||
NR6A1 | Nuclear receptor subfamily 6 group A member 1. (457 aa) | ||||
NR2F1 | Nuclear receptor subfamily 2 group F member 1. (423 aa) | ||||
NR2C2AP | Nuclear receptor 2C2 associated protein. (167 aa) | ||||
PGR | Progesterone receptor. (936 aa) | ||||
AR | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. (895 aa) | ||||
ESR2 | Estrogen receptor 2. (530 aa) | ||||
PPARD | Peroxisome proliferator activated receptor delta. (441 aa) | ||||
RXRB | Retinoid X receptor beta. (537 aa) | ||||
NR4A2 | Nuclear receptor subfamily 4 group A member 2. (598 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) | ||||
NCOR1 | Nuclear receptor corepressor 1. (2442 aa) | ||||
NR1D1 | Nuclear receptor subfamily 1 group D member 1. (613 aa) | ||||
VDR | Vitamin D receptor. (477 aa) | ||||
NR1D2 | Nuclear receptor subfamily 1 group D member 2. (580 aa) | ||||
RARA | Retinoic acid receptor alpha. (462 aa) | ||||
RARB | Retinoic acid receptor beta. (448 aa) | ||||
RORB | RAR related orphan receptor B. (475 aa) | ||||
CEP55 | Centrosomal protein 55. (464 aa) | ||||
ENSMFAP00000042405 | Uncharacterized protein. (232 aa) | ||||
ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) | ||||
NR1H2 | Nuclear receptor subfamily 1 group H member 2. (461 aa) | ||||
C1orf56 | Chromosome 1 open reading frame 56. (341 aa) | ||||
NR3C1 | Nuclear receptor subfamily 3 group C member 1. (778 aa) | ||||
NR2E1 | Nuclear receptor subfamily 2 group E member 1. (385 aa) | ||||
NR4A3 | Nuclear receptor subfamily 4 group A member 3. (637 aa) | ||||
NR1H3 | Nuclear receptor subfamily 1 group H member 3. (453 aa) | ||||
RXRG | Retinoid X receptor gamma. (463 aa) | ||||
NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) | ||||
NCOR2 | Nuclear receptor corepressor 2. (2510 aa) | ||||
NR0B2 | Nuclear receptor subfamily 0 group B member 2. (257 aa) | ||||
NR3C2 | Nuclear receptor subfamily 3 group C member 2. (988 aa) | ||||
NR1I2 | Nuclear receptor subfamily 1 group I member 2. (473 aa) | ||||
NR5A2 | Nuclear receptor subfamily 5 group A member 2. (541 aa) | ||||
ESRRB | Estrogen related receptor beta. (438 aa) | ||||
RORC | RAR related orphan receptor C. (518 aa) | ||||
NR2C1 | Nuclear receptor subfamily 2 group C member 1; Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiatio [...] (603 aa) | ||||
ESRRG | Estrogen related receptor gamma. (470 aa) | ||||
THRB | Uncharacterized protein. (476 aa) | ||||
RARG | Retinoic acid receptor gamma. (454 aa) | ||||
NRBP1 | Nuclear receptor-binding protein; May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (543 aa) | ||||
CCDC134 | Coiled-coil domain containing 134. (229 aa) | ||||
PPARA | Peroxisome proliferator activated receptor alpha. (467 aa) | ||||
NRBF2 | Nuclear receptor binding factor 2. (289 aa) | ||||
THRA | Uncharacterized protein. (602 aa) |