node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FFAR1 | GNA11 | ENSMFAP00000011333 | ENSMFAP00000041087 | Free fatty acid receptor 1; G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular c [...] | G protein subunit alpha 11. | 0.939 |
FFAR1 | GNA14 | ENSMFAP00000011333 | ENSMFAP00000022690 | Free fatty acid receptor 1; G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular c [...] | G protein subunit alpha 14. | 0.416 |
FFAR1 | GNA15 | ENSMFAP00000011333 | ENSMFAP00000045710 | Free fatty acid receptor 1; G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular c [...] | G protein subunit alpha 15. | 0.499 |
FFAR1 | GNAQ | ENSMFAP00000011333 | ENSMFAP00000034906 | Free fatty acid receptor 1; G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular c [...] | G protein subunit alpha q. | 0.961 |
GNA11 | FFAR1 | ENSMFAP00000041087 | ENSMFAP00000011333 | G protein subunit alpha 11. | Free fatty acid receptor 1; G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular c [...] | 0.939 |
GNA11 | GNA15 | ENSMFAP00000041087 | ENSMFAP00000045710 | G protein subunit alpha 11. | G protein subunit alpha 15. | 0.470 |
GNA11 | GNAQ | ENSMFAP00000041087 | ENSMFAP00000034906 | G protein subunit alpha 11. | G protein subunit alpha q. | 0.926 |
GNA11 | PLCB1 | ENSMFAP00000041087 | ENSMFAP00000023653 | G protein subunit alpha 11. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.961 |
GNA11 | PLCB2 | ENSMFAP00000041087 | ENSMFAP00000032339 | G protein subunit alpha 11. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.959 |
GNA11 | PLCB3 | ENSMFAP00000041087 | ENSMFAP00000027132 | G protein subunit alpha 11. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.969 |
GNA14 | FFAR1 | ENSMFAP00000022690 | ENSMFAP00000011333 | G protein subunit alpha 14. | Free fatty acid receptor 1; G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular c [...] | 0.416 |
GNA14 | GNA15 | ENSMFAP00000022690 | ENSMFAP00000045710 | G protein subunit alpha 14. | G protein subunit alpha 15. | 0.472 |
GNA14 | PLCB1 | ENSMFAP00000022690 | ENSMFAP00000023653 | G protein subunit alpha 14. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.961 |
GNA14 | PLCB2 | ENSMFAP00000022690 | ENSMFAP00000032339 | G protein subunit alpha 14. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.986 |
GNA14 | PLCB3 | ENSMFAP00000022690 | ENSMFAP00000027132 | G protein subunit alpha 14. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.969 |
GNA15 | FFAR1 | ENSMFAP00000045710 | ENSMFAP00000011333 | G protein subunit alpha 15. | Free fatty acid receptor 1; G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular c [...] | 0.499 |
GNA15 | GNA11 | ENSMFAP00000045710 | ENSMFAP00000041087 | G protein subunit alpha 15. | G protein subunit alpha 11. | 0.470 |
GNA15 | GNA14 | ENSMFAP00000045710 | ENSMFAP00000022690 | G protein subunit alpha 15. | G protein subunit alpha 14. | 0.472 |
GNA15 | GNAQ | ENSMFAP00000045710 | ENSMFAP00000034906 | G protein subunit alpha 15. | G protein subunit alpha q. | 0.447 |
GNA15 | PLCB1 | ENSMFAP00000045710 | ENSMFAP00000023653 | G protein subunit alpha 15. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.956 |