STRINGSTRING
SEC13 SEC13 NUP88 NUP88 SCMH1 SCMH1 NUP188 NUP188 NUP210L NUP210L NUP58 NUP58 NUP93 NUP93 SCML2 SCML2 SATB1 SATB1 NUP85 NUP85 ENSMFAP00000029118 ENSMFAP00000029118 SUMO1-2 SUMO1-2 ENSMFAP00000027910 ENSMFAP00000027910 NUP98 NUP98 ENSMFAP00000026148 ENSMFAP00000026148 CBX8 CBX8 PCGF2 PCGF2 PHC3 PHC3 POM121C POM121C KCTD2 KCTD2 HDAC1 HDAC1 ZNF618 ZNF618 NUP35 NUP35 ENSMFAP00000009974 ENSMFAP00000009974 SEH1L SEH1L ENSMFAP00000010148 ENSMFAP00000010148 NDC1 NDC1 ENSMFAP00000010517 ENSMFAP00000010517 LOC102138794 LOC102138794 ENSMFAP00000010659 ENSMFAP00000010659 ENSMFAP00000010686 ENSMFAP00000010686 PHC2 PHC2 NUP50 NUP50 SATB2 SATB2 NUP43 NUP43 RAE1 RAE1 ENSMFAP00000025317 ENSMFAP00000025317 NUP133 NUP133 UBE2I UBE2I NUP210 NUP210 SUMO3-2 SUMO3-2 ENSMFAP00000010848 ENSMFAP00000010848 ENSMFAP00000010867 ENSMFAP00000010867 ENSMFAP00000010884 ENSMFAP00000010884 PHC1 PHC1 ENSMFAP00000011138 ENSMFAP00000011138 ENSMFAP00000012391 ENSMFAP00000012391 ZBED1 ZBED1 CHD3 CHD3 SUMO2 SUMO2 NFATC2IP NFATC2IP ENSMFAP00000013484 ENSMFAP00000013484 ZBED4 ZBED4 RANBP2 RANBP2 G7PB98_MACFA G7PB98_MACFA CBX4 CBX4 ENSMFAP00000015065 ENSMFAP00000015065 ENSMFAP00000015119 ENSMFAP00000015119 ENSMFAP00000015138 ENSMFAP00000015138 ENSMFAP00000015196 ENSMFAP00000015196 SUMO1 SUMO1 NUP54 NUP54 CBX2 CBX2 NUP160 NUP160 NUP42 NUP42 NUP62 NUP62 ENSMFAP00000033991 ENSMFAP00000033991 ENSMFAP00000034417 ENSMFAP00000034417 ENSMFAP00000034482 ENSMFAP00000034482 CBX5 CBX5 SHLD1 SHLD1 ENSMFAP00000036744 ENSMFAP00000036744 L3MBTL2 L3MBTL2 ENSMFAP00000037126 ENSMFAP00000037126 NUP205 NUP205 BMI1 BMI1 PIAS1 PIAS1 AAAS AAAS SUZ12 SUZ12 NUP155 NUP155 ENSMFAP00000043974 ENSMFAP00000043974 NUP37 NUP37 RNF2 RNF2 RING1 RING1 LOC102128732 LOC102128732 NUP214 NUP214 LOC102138275 LOC102138275 LOC102121517 LOC102121517 NUP153 NUP153 NUP62CL NUP62CL HDAC2 HDAC2 HDAC4 HDAC4 TPR TPR NUP107 NUP107 SUMO3 SUMO3 PIAS2 PIAS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa)
NUP88Nucleoporin 88. (741 aa)
SCMH1SAM domain-containing protein. (660 aa)
NUP188Nucleoporin 188. (1749 aa)
NUP210LNucleoporin 210 like. (1861 aa)
NUP58Nucleoporin 58. (599 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa)
SCML2Scm polycomb group protein like 2. (701 aa)
SATB1DNA-binding protein SATB. (795 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
ENSMFAP00000029118Small ubiquitin-related modifier. (104 aa)
SUMO1-2Rad60-SLD domain-containing protein. (67 aa)
ENSMFAP00000027910Rad60-SLD domain-containing protein. (81 aa)
NUP98Nucleoporin 98. (1610 aa)
ENSMFAP00000026148Small ubiquitin-related modifier. (95 aa)
CBX8Chromobox 8. (420 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
PHC3Polyhomeotic homolog 3. (995 aa)
POM121CUncharacterized protein. (1225 aa)
KCTD2Potassium channel tetramerization domain containing 2. (263 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
ZNF618Zinc finger protein 618. (1012 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (326 aa)
ENSMFAP00000009974Histone H4. (103 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (360 aa)
ENSMFAP00000010148Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (421 aa)
NDC1NDC1 transmembrane nucleoporin. (523 aa)
ENSMFAP00000010517Histone H4. (103 aa)
LOC102138794RING-type domain-containing protein. (321 aa)
ENSMFAP00000010659WD_REPEATS_REGION domain-containing protein. (377 aa)
ENSMFAP00000010686Histone H4. (103 aa)
PHC2Polyhomeotic homolog 2. (859 aa)
NUP50Testis cDNA clone: QtsA-12809, similar to human nucleoporin 50kDa (NUP50), transcript variant 2. (468 aa)
SATB2DNA-binding protein SATB. (733 aa)
NUP43WD_REPEATS_REGION domain-containing protein. (380 aa)
RAE1mRNA export factor; Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. (368 aa)
ENSMFAP00000025317Hist_deacetyl domain-containing protein. (258 aa)
NUP133Nucleoporin 133. (1156 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
NUP210Nucleoporin 210. (1887 aa)
SUMO3-2Ubiquitin-like domain-containing protein. (141 aa)
ENSMFAP00000010848Histone H4. (103 aa)
ENSMFAP00000010867Histone H4. (103 aa)
ENSMFAP00000010884Histone H4. (103 aa)
PHC1Polyhomeotic homolog 1. (1003 aa)
ENSMFAP00000011138Histone H4. (103 aa)
ENSMFAP00000012391Ubiquitin-like domain-containing protein. (132 aa)
ZBED1Zinc finger BED-type containing 1. (694 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2000 aa)
SUMO2Small ubiquitin-related modifier 2; Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO [...] (95 aa)
NFATC2IPNFATC2-interacting protein; In T-helper 2 (Th2) cells, regulates the magnitude of NFAT- driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity). Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity). (468 aa)
ENSMFAP00000013484Histone H4. (103 aa)
ZBED4Zinc finger BED-type containing 4. (1171 aa)
RANBP2RAN binding protein 2. (3221 aa)
G7PB98_MACFASmall ubiquitin-related modifier. (95 aa)
CBX4Chromobox 4. (558 aa)
ENSMFAP00000015065Histone H4. (103 aa)
ENSMFAP00000015119Histone H4. (103 aa)
ENSMFAP00000015138Histone H4. (103 aa)
ENSMFAP00000015196Histone H4. (103 aa)
SUMO1Ubiquitin-like domain-containing protein. (146 aa)
NUP54Testis cDNA, clone: QtsA-18807, similar to human nucleoporin 54kDa (NUP54). (508 aa)
CBX2Chromobox 2. (555 aa)
NUP160Nucleoporin 160. (1436 aa)
NUP42Nucleoporin 42. (435 aa)
NUP62Nucleoporin 62. (338 aa)
ENSMFAP00000033991Uncharacterized protein. (418 aa)
ENSMFAP00000034417Uncharacterized protein. (422 aa)
ENSMFAP00000034482Rad60-SLD domain-containing protein. (86 aa)
CBX5Chromobox 5. (191 aa)
SHLD1Shieldin complex subunit 1. (269 aa)
ENSMFAP00000036744Uncharacterized protein. (90 aa)
L3MBTL2L3MBTL histone methyl-lysine binding protein 2. (705 aa)
ENSMFAP00000037126Rad60-SLD domain-containing protein. (71 aa)
NUP205Nucleoporin 205. (2013 aa)
BMI1RING-type domain-containing protein. (326 aa)
PIAS1Uncharacterized protein. (653 aa)
AAASAladin WD repeat nucleoporin. (546 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
NUP155Nucleoporin 155. (1449 aa)
ENSMFAP00000043974Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (462 aa)
NUP37Nucleoporin 37. (326 aa)
RNF2Ring finger protein 2. (336 aa)
RING1Ring finger protein 1. (412 aa)
LOC102128732Rad60-SLD domain-containing protein. (94 aa)
NUP214Nucleoporin 214. (2090 aa)
LOC102138275Histone H4. (103 aa)
LOC102121517Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (103 aa)
NUP153Nucleoporin 153. (1492 aa)
NUP62CLNsp1_C domain-containing protein. (238 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1085 aa)
TPRTranslocated promoter region, nuclear basket protein. (2439 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
SUMO3Ubiquitin-like domain-containing protein. (137 aa)
PIAS2Protein inhibitor of activated STAT 2. (620 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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