| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD4 | CD40LG | ENSMFAP00000041028 | ENSMFAP00000029048 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | 0.903 |
| CD4 | CD55 | ENSMFAP00000041028 | ENSMFAP00000043471 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | CD55 molecule (Cromer blood group). | 0.688 |
| CD4 | CTLA4 | ENSMFAP00000041028 | ENSMFAP00000031091 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Cytotoxic T-lymphocyte associated protein 4. | 0.973 |
| CD4 | SERPINA1 | ENSMFAP00000041028 | ENSMFAP00000022414 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Serpin family A member 1; Belongs to the serpin family. | 0.479 |
| CD4 | SIGLEC1 | ENSMFAP00000041028 | ENSMFAP00000041268 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Sialic acid binding Ig like lectin 1. | 0.665 |
| CD4 | VWF | ENSMFAP00000041028 | ENSMFAP00000044374 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Von Willebrand factor. | 0.503 |
| CD40LG | CD4 | ENSMFAP00000029048 | ENSMFAP00000041028 | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.903 |
| CD40LG | CTLA4 | ENSMFAP00000029048 | ENSMFAP00000031091 | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | Cytotoxic T-lymphocyte associated protein 4. | 0.718 |
| CD55 | CD4 | ENSMFAP00000043471 | ENSMFAP00000041028 | CD55 molecule (Cromer blood group). | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.688 |
| CD55 | CTLA4 | ENSMFAP00000043471 | ENSMFAP00000031091 | CD55 molecule (Cromer blood group). | Cytotoxic T-lymphocyte associated protein 4. | 0.547 |
| CD55 | LOC102142214 | ENSMFAP00000043471 | ENSMFAP00000021352 | CD55 molecule (Cromer blood group). | Rieske domain-containing protein. | 0.404 |
| CD55 | TFPI | ENSMFAP00000043471 | ENSMFAP00000011561 | CD55 molecule (Cromer blood group). | Tissue factor pathway inhibitor. | 0.511 |
| CD55 | TFPI2 | ENSMFAP00000043471 | ENSMFAP00000021910 | CD55 molecule (Cromer blood group). | Tissue factor pathway inhibitor. | 0.470 |
| CTLA4 | CD4 | ENSMFAP00000031091 | ENSMFAP00000041028 | Cytotoxic T-lymphocyte associated protein 4. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.973 |
| CTLA4 | CD40LG | ENSMFAP00000031091 | ENSMFAP00000029048 | Cytotoxic T-lymphocyte associated protein 4. | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | 0.718 |
| CTLA4 | CD55 | ENSMFAP00000031091 | ENSMFAP00000043471 | Cytotoxic T-lymphocyte associated protein 4. | CD55 molecule (Cromer blood group). | 0.547 |
| CTLA4 | TFPI | ENSMFAP00000031091 | ENSMFAP00000011561 | Cytotoxic T-lymphocyte associated protein 4. | Tissue factor pathway inhibitor. | 0.413 |
| GLA | LOC102142214 | ENSMFAP00000019006 | ENSMFAP00000021352 | Alpha-galactosidase. | Rieske domain-containing protein. | 0.442 |
| LOC102142214 | CD55 | ENSMFAP00000021352 | ENSMFAP00000043471 | Rieske domain-containing protein. | CD55 molecule (Cromer blood group). | 0.404 |
| LOC102142214 | GLA | ENSMFAP00000021352 | ENSMFAP00000019006 | Rieske domain-containing protein. | Alpha-galactosidase. | 0.442 |