STRINGSTRING
PI4KB PI4KB SOD3 SOD3 ENSMFAP00000012434 ENSMFAP00000012434 ENSMFAP00000012966 ENSMFAP00000012966 NT5C NT5C PNLIPRP3 PNLIPRP3 AADAC AADAC IP6K2 IP6K2 ACOT2 ACOT2 PPIP5K2 PPIP5K2 PGAM2 PGAM2 NT5E NT5E PI4K2B PI4K2B ENSMFAP00000020710 ENSMFAP00000020710 NT5M NT5M SMPD1 SMPD1 LIPF LIPF NT5C2 NT5C2 ACOT4 ACOT4 HPGDS HPGDS PI3 PI3 LIPC LIPC PLAT PLAT DHDH DHDH NT5C1B NT5C1B AKR1C1 AKR1C1 PI4K2A PI4K2A PGAM1 PGAM1 NT5C1A NT5C1A PTGDS PTGDS AKR1C1-2 AKR1C1-2 PTGES PTGES SOD2 SOD2 NT5C3A NT5C3A PNLIPRP1 PNLIPRP1 SOD1 SOD1 PNLIPRP2 PNLIPRP2 LIPG LIPG IP6K3 IP6K3 IP6K1 IP6K1 PI4KA PI4KA TXN TXN PNLIP PNLIP APEX2 APEX2 APEX1 APEX1 PTGES2 PTGES2 PNPLA3 PNPLA3 G7P3Z5_MACFA G7P3Z5_MACFA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (832 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (240 aa)
ENSMFAP00000012434Thioredoxin; Belongs to the thioredoxin family. (105 aa)
ENSMFAP00000012966Thioredoxin; Belongs to the thioredoxin family. (105 aa)
NT5C5', 3'-nucleotidase, cytosolic. (201 aa)
PNLIPRP3Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (473 aa)
AADACArylacetamide deacetylase. (399 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (478 aa)
ACOT2Uncharacterized protein. (463 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1278 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2 beta. (481 aa)
ENSMFAP00000020710Thioredoxin; Belongs to the thioredoxin family. (101 aa)
NT5M5',3'-nucleotidase, mitochondrial. (228 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (629 aa)
LIPFLipase; Belongs to the AB hydrolase superfamily. Lipase family. (408 aa)
NT5C25'-nucleotidase, cytosolic II. (572 aa)
ACOT4Acyl-CoA thioesterase 4. (421 aa)
HPGDSHematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa)
PI3Peptidase inhibitor 3. (117 aa)
LIPCLipase C, hepatic type. (523 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
DHDHTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Belongs to the Gfo/Idh/MocA family. (334 aa)
NT5C1BUncharacterized protein. (610 aa)
AKR1C1Aldo-keto reductase family 1 member C1 homolog; Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. May play a role in myelin formation. Can oxidize both 20-alpha- and 3-alpha-hydroxysteroids. Low activity towards 5-alpha-androstan-17-beta-ol-3-one. Can also act on non-steroidal substrates such as S-indan-1-ol, S-tetralol and 4- chromanol; Belongs to the aldo/keto reductase family. (323 aa)
PI4K2APhosphatidylinositol 4-kinase type 2 alpha. (480 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (256 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (371 aa)
PTGDSLipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
AKR1C1-2Aldo_ket_red domain-containing protein. (366 aa)
PTGESProstaglandin E synthase; Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). (163 aa)
SOD2Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (336 aa)
PNLIPRP1Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (530 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
LIPGLipase G, endothelial type. (500 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (410 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2077 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
PNLIPTriacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
APEX2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (518 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (324 aa)
PTGES2Prostaglandin E synthase 2 truncated form; Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2); Belongs to the GST superfamily. (377 aa)
PNPLA3Patatin like phospholipase domain containing 3. (507 aa)
G7P3Z5_MACFAThioredoxin; Belongs to the thioredoxin family. (102 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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