STRINGSTRING
XPR1 XPR1 GDF15 GDF15 ENSMFAP00000029118 ENSMFAP00000029118 ENSMFAP00000026148 ENSMFAP00000026148 VTN VTN PTH PTH IP6K2 IP6K2 SPX SPX G7PB98_MACFA G7PB98_MACFA G7PFU7_MACFA G7PFU7_MACFA IP6K1 IP6K1 ALB ALB IP6K3 IP6K3 IPMK IPMK ENSMFAP00000000815 ENSMFAP00000000815 FGF23 FGF23
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XPR1Xenotropic and polytropic retrovirus receptor 1. (688 aa)
GDF15Growth/differentiation factor 15; Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions. On hepatocytes, inhibits growth hormone signaling (By similarity). (308 aa)
ENSMFAP00000029118Small ubiquitin-related modifier. (104 aa)
ENSMFAP00000026148Small ubiquitin-related modifier. (95 aa)
VTNSMB domain-containing protein. (479 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity). (115 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (478 aa)
SPXSpexin hormone. (116 aa)
G7PB98_MACFASmall ubiquitin-related modifier. (95 aa)
G7PFU7_MACFASmall ubiquitin-related modifier. (101 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (608 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (410 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (416 aa)
ENSMFAP00000000815Small ubiquitin-related modifier. (121 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (18%) [HD]