STRINGSTRING
ANGPT1 ANGPT1 IL6 IL6 SERPINE1 SERPINE1 VWF VWF IDO2 IDO2 PLAU PLAU PTX3 PTX3 ENSMFAP00000034298 ENSMFAP00000034298 STAT1 STAT1 GATA3 GATA3 ADAMTS13 ADAMTS13 IDO1 IDO1 ITGB2 ITGB2 HIST1H3B HIST1H3B LOC102147067 LOC102147067 ENSMFAP00000010627 ENSMFAP00000010627 TFPI TFPI LOC102130997 LOC102130997 ENSMFAP00000012034 ENSMFAP00000012034 H3-4 H3-4 ENSMFAP00000012162 ENSMFAP00000012162 ICAM1 ICAM1 LOC102146894 LOC102146894 G8F5U3_MACFA G8F5U3_MACFA MPO MPO TFPI2 TFPI2 H3F3B H3F3B ENSMFAP00000022290 ENSMFAP00000022290 F10 F10 IFNG IFNG THPO THPO ANGPT2 ANGPT2 KLKB1 KLKB1 PLAT PLAT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANGPT1Angiopoietin 1. (498 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (212 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
VWFVon Willebrand factor. (2813 aa)
IDO2Indoleamine 2,3-dioxygenase 2. (420 aa)
PLAUPlasminogen activator, urokinase. (430 aa)
PTX3Pentraxin 3. (381 aa)
ENSMFAP00000034298Histone H3; Belongs to the histone H3 family. (141 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
GATA3GATA binding protein 3. (444 aa)
ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13. (1431 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (403 aa)
ITGB2Integrin beta. (874 aa)
HIST1H3BHistone H3; Belongs to the histone H3 family. (136 aa)
LOC102147067Histone H3; Belongs to the histone H3 family. (136 aa)
ENSMFAP00000010627Histone H3; Belongs to the histone H3 family. (136 aa)
TFPITissue factor pathway inhibitor. (304 aa)
LOC102130997Histone H3; Belongs to the histone H3 family. (136 aa)
ENSMFAP00000012034Histone H3; Belongs to the histone H3 family. (136 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
ENSMFAP00000012162Histone H3; Belongs to the histone H3 family. (136 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
LOC102146894Histone domain-containing protein. (136 aa)
G8F5U3_MACFAHistone H3; Belongs to the histone H3 family. (136 aa)
MPOMyeloperoxidase. (745 aa)
TFPI2Tissue factor pathway inhibitor. (235 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
ENSMFAP00000022290Histone domain-containing protein. (113 aa)
F10Coagulation factor X. (488 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
THPOThrombopoietin. (353 aa)
ANGPT2Angiopoietin 2. (496 aa)
KLKB1Kallikrein B1; Belongs to the peptidase S1 family. (638 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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