STRINGSTRING
GRIA1 GRIA1 NRXN1 NRXN1 NRXN3 NRXN3 ADAM22 ADAM22 FOXP2 FOXP2 CNTNAP2 CNTNAP2 CNTN2 CNTN2 GPR37 GPR37 EGF EGF NRXN2 NRXN2 LGI1 LGI1 DLX2 DLX2 ASCL1 ASCL1 PVALB PVALB CNTN1 CNTN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRIA1Glutamate receptor 1; Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulati [...] (916 aa)
NRXN1Neurexin 1. (1507 aa)
NRXN3Neurexin 3. (1664 aa)
ADAM22ADAM metallopeptidase domain 22. (935 aa)
FOXP2Forkhead box P2. (739 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
CNTN2Contactin 2. (1040 aa)
GPR37G protein-coupled receptor 37. (613 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
NRXN2Neurexin 2. (1713 aa)
LGI1Leucine rich glioma inactivated 1. (557 aa)
DLX2Distal-less homeobox 2. (328 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (238 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (110 aa)
CNTN1Contactin 1. (1018 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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