STRINGSTRING
CALML6 CALML6 SIM1 SIM1 PCNA PCNA PRKACB PRKACB HIF1A HIF1A PRKACG PRKACG FOS FOS CALML3 CALML3 PRKACA PRKACA ARG2 ARG2 CALML4 CALML4 CALM3 CALM3 ENSMFAP00000004513 ENSMFAP00000004513 RHOA RHOA TGFB1 TGFB1 VGF VGF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALML6Calmodulin like 6. (181 aa)
SIM1SIM bHLH transcription factor 1. (766 aa)
PCNAProliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] (261 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
HIF1AUncharacterized protein. (831 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (333 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ARG2Arginase. (354 aa)
CALML4Calmodulin like 4. (193 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
ENSMFAP00000004513Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (252 aa)
RHOAUncharacterized protein. (141 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
VGFVGF nerve growth factor inducible. (615 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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