STRINGSTRING
RGL1 RGL1 ENSMFAP00000017798 ENSMFAP00000017798 SOS1 SOS1 RASGRP1 RASGRP1 RASGEF1C RASGEF1C RAPGEFL1 RAPGEFL1 RALGPS2 RALGPS2 LOC102145495 LOC102145495 RAPGEF5 RAPGEF5 RGL3 RGL3 ENSMFAP00000009762 ENSMFAP00000009762 LOC102115767 LOC102115767 SOS2 SOS2 SH2D3C SH2D3C RAPGEF6 RAPGEF6 RASGRP4 RASGRP4 RALGDS RALGDS RAPGEF2 RAPGEF2 RASGEF1A RASGEF1A ENSMFAP00000025893 ENSMFAP00000025893 RAPGEF4 RAPGEF4 LOC102143669 LOC102143669 RASGRP3 RASGRP3 BCAR3 BCAR3 RASGEF1B RASGEF1B PLCE1 PLCE1 LOC102134476 LOC102134476 RASGRP2 RASGRP2 ENSMFAP00000044716 ENSMFAP00000044716 LOC102116894 LOC102116894 RASGRF2 RASGRF2 RASGRF1 RASGRF1 ENSMFAP00000034139 ENSMFAP00000034139 RAPGEF3 RAPGEF3 RALGPS1 RALGPS1 RAPGEF1 RAPGEF1 ENSMFAP00000041150 ENSMFAP00000041150 RGL2 RGL2 LOC102145064 LOC102145064
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RGL1Ral guanine nucleotide dissociation stimulator like 1. (803 aa)
ENSMFAP00000017798Ras-GEF domain-containing protein. (400 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa)
RASGRP1RAS guanyl releasing protein 1. (842 aa)
RASGEF1CRas-GEF domain-containing family member 1C; Guanine nucleotide exchange factor (GEF). (466 aa)
RAPGEFL1Rap guanine nucleotide exchange factor like 1. (662 aa)
RALGPS2Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion. (583 aa)
LOC102145495Ras-GEF domain-containing protein. (536 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (883 aa)
RGL3Ral guanine nucleotide dissociation stimulator like 3. (696 aa)
ENSMFAP00000009762Ras-GEF domain-containing protein. (522 aa)
LOC102115767Ras-GEF domain-containing protein. (590 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
SH2D3CSH2 domain containing 3C. (856 aa)
RAPGEF6Uncharacterized protein. (1609 aa)
RASGRP4RAS guanyl releasing protein 4. (673 aa)
RALGDSUncharacterized protein. (902 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1701 aa)
RASGEF1ARasGEF domain family member 1A. (505 aa)
ENSMFAP00000025893Ras-GEF domain-containing protein. (408 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1011 aa)
LOC102143669Ras-GEF domain-containing protein. (597 aa)
RASGRP3RAS guanyl releasing protein 3. (734 aa)
BCAR3Breast cancer anti-estrogen resistance protein 3 homolog; Acts as an adapter protein downstream of several growth factor receptors to promote cell proliferation, migration, and redistribution of actin fibers (By similarity). Specifically involved in INS/insulin signaling pathway by mediating MAPK1/ERK2-MAPK3/ERK1 activation and DNA synthesis (By similarity). Promotes insulin-mediated membrane ruffling (By similarity). In response to vasoconstrictor peptide EDN1, involved in the activation of RAP1 downstream of PTK2B via interaction with phosphorylated BCAR1. Inhibits cell migration and [...] (823 aa)
RASGEF1BRasGEF domain family member 1B. (560 aa)
PLCE1Phosphoinositide phospholipase C. (2303 aa)
LOC102134476Ras-GEF domain-containing protein. (500 aa)
RASGRP2RAS guanyl releasing protein 2. (609 aa)
ENSMFAP00000044716Ras-GEF domain-containing protein. (527 aa)
LOC102116894Ras-GEF domain-containing protein. (469 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1237 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1273 aa)
ENSMFAP00000034139Ras-GEF domain-containing protein. (525 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
RALGPS1Ral GEF with PH domain and SH3 binding motif 1. (585 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1099 aa)
ENSMFAP00000041150Ras-GEF domain-containing protein. (525 aa)
RGL2Ral guanine nucleotide dissociation stimulator like 2. (777 aa)
LOC102145064Ras-GEF domain-containing protein. (473 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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