STRINGSTRING
TGFA TGFA TEK TEK F9 F9 SLIT1 SLIT1 STAB1 STAB1 CELSR3 CELSR3 LRP2 LRP2 SCARF2 SCARF2 UMOD UMOD EGFL6 EGFL6 FBN2 FBN2 PLAT PLAT CNTNAP5 CNTNAP5 CRELD2 CRELD2 LDLR LDLR CRB2 CRB2 PROZ PROZ HYAL4 HYAL4 MATN2 MATN2 SELL SELL MEGF6 MEGF6 DLL4 DLL4 LRP1B LRP1B NRG2 NRG2 VWCE VWCE TIE1 TIE1 NRXN2 NRXN2 HYAL1 HYAL1 TENM2 TENM2 ASTN1 ASTN1 LTBP3 LTBP3 ATRNL1 ATRNL1 EGF EGF LRP4 LRP4 FBLN2 FBLN2 COMP COMP HHIP HHIP CELSR1 CELSR1 SCUBE2 SCUBE2 STAB2 STAB2 DNER DNER MUC17 MUC17 FAT1 FAT1 HABP2 HABP2 MFGE8 MFGE8 JAG2 JAG2 ADGRE2 ADGRE2 WIF1 WIF1 AGRN AGRN THBS3 THBS3 PLAU PLAU NRXN1 NRXN1 MUC13 MUC13 MEP1B MEP1B NPNT NPNT CNTNAP1 CNTNAP1 DLL3 DLL3 TENM4 TENM4 CNTNAP2 CNTNAP2 PTGS1 PTGS1 MALRD1 MALRD1 NOTCH3 NOTCH3 FAT2 FAT2 EDIL3 EDIL3 NELL2 NELL2 NTNG2 NTNG2 DLL1 DLL1 ADAM28 ADAM28 UMODL1 UMODL1 FBN1 FBN1 NRG3 NRG3 LRP1 LRP1 ADAM9 ADAM9 LTBP2 LTBP2 ADGRE1 ADGRE1 BTC BTC ITGB8 ITGB8 NOTCH1 NOTCH1 FAT4 FAT4 HYAL2 HYAL2 PTGS2 PTGS2 ENSMFAP00000012945 ENSMFAP00000012945 NID1 NID1 SCUBE1 SCUBE1 VASN VASN ENSMFAP00000012280 ENSMFAP00000012280 VWA2 VWA2 ATRAID ATRAID NAGPA NAGPA PEAR1 PEAR1 LOC101865400 LOC101865400 ITGB5 ITGB5 LOC102128314 LOC102128314 MSANTD3-TMEFF1 MSANTD3-TMEFF1 LOC102138242 LOC102138242 CNTNAP3B CNTNAP3B BCAN BCAN EREG EREG SLIT3 SLIT3 CRELD1 CRELD1 ADAM22 ADAM22 NOTCH2 NOTCH2 SELE SELE ENSMFAP00000008086 ENSMFAP00000008086 AREG AREG PAMR1 PAMR1 RELN RELN TENM1 TENM1 ATRN ATRN HEG1 HEG1 TDGF1 TDGF1 HGFAC HGFAC TNXB TNXB NRG1 NRG1 TMEM8B TMEM8B TNC TNC CNTNAP4 CNTNAP4 MMRN1 MMRN1 MUC4 MUC4 SNED1 SNED1 PGAP6 PGAP6 EGFLAM EGFLAM TENM3 TENM3 DLK2 DLK2 VWDE VWDE FBN3 FBN3 NTNG1 NTNG1 ITGBL1 ITGBL1 BRINP2 BRINP2 CSPG5 CSPG5 MEP1A MEP1A BRINP3 BRINP3 CRB1 CRB1 DLK1 DLK1 MEGF11 MEGF11 CCBE1 CCBE1 HMCN1 HMCN1 CELSR2 CELSR2 SELP SELP NID2 NID2 ZAN ZAN NRG4 NRG4 SLIT2 SLIT2 THBS2 THBS2 MATN3 MATN3 CD248 CD248 SVEP1 SVEP1 NCAN NCAN GAS6 GAS6 HYAL3 HYAL3 CD93 CD93 F10 F10 HBEGF HBEGF MEGF8 MEGF8 ENSMFAP00000025099 ENSMFAP00000025099 ADAM15 ADAM15 ADAM33 ADAM33 MEGF10 MEGF10 EGFL7 EGFL7 FBLN1 FBLN1 LRP6 LRP6 SCUBE3 SCUBE3 LOC102123198 LOC102123198 FAT3 FAT3 NELL1 NELL1 TECTA TECTA SUSD1 SUSD1 ADAM11 ADAM11 PROS1 PROS1 F7 F7 THBS4 THBS4 IMPG1 IMPG1 JAG1 JAG1 EFEMP2 EFEMP2 NOTCH4 NOTCH4 THBS1 THBS1 EPGN EPGN OIT3 OIT3 ADGRL4 ADGRL4 VCAN VCAN F12 F12 VLDLR VLDLR MUC3A MUC3A EYS EYS SCARF1 SCARF1 MATN1 MATN1 TMEFF2 TMEFF2 NRXN3 NRXN3 SORL1 SORL1 LTBP4 LTBP4 LRP8 LRP8 RSPO3 RSPO3 CUBN CUBN HSPG2 HSPG2 ADAM23 ADAM23 LTBP1 LTBP1 ENSMFAP00000026040 ENSMFAP00000026040 PROC PROC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFATransforming growth factor alpha. (166 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
F9Coagulation factor IX. (461 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
STAB1Stabilin 1. (2568 aa)
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3324 aa)
LRP2LDL receptor related protein 2. (4655 aa)
SCARF2Scavenger receptor class F member 2. (823 aa)
UMODUromodulin. (641 aa)
EGFL6EGF like domain multiple 6. (649 aa)
FBN2Fibrillin 2. (2912 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
CNTNAP5Contactin associated protein like 5. (1307 aa)
CRELD2Cysteine rich with EGF like domains 2. (415 aa)
LDLRLow density lipoprotein receptor. (860 aa)
CRB2Crumbs cell polarity complex component 2. (1350 aa)
PROZProtein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (422 aa)
HYAL4Hyaluronidase. (481 aa)
MATN2Matrilin 2. (937 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (385 aa)
MEGF6Multiple EGF like domains 6. (1541 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
LRP1BLDL receptor related protein 1B. (4599 aa)
NRG2Neuregulin 2. (630 aa)
VWCEVon Willebrand factor C and EGF domains. (955 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
NRXN2Neurexin 2. (1713 aa)
HYAL1Hyaluronidase. (435 aa)
TENM2Teneurin transmembrane protein 2. (2774 aa)
ASTN1Astrotactin 1. (1294 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1298 aa)
ATRNL1Attractin like 1. (1378 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
LRP4LDL receptor related protein 4. (1913 aa)
FBLN2Fibulin 2. (1225 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
HHIPHedgehog interacting protein. (682 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2968 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (961 aa)
STAB2Stabilin 2. (2554 aa)
DNERDelta/notch like EGF repeat containing. (709 aa)
MUC17SEA domain-containing protein. (3964 aa)
FAT1FAT atypical cadherin 1. (4623 aa)
HABP2Hyaluronan binding protein 2. (560 aa)
MFGE8Milk fat globule-EGF factor 8 protein. (387 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1075 aa)
ADGRE2Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family. (557 aa)
WIF1WNT inhibitory factor 1. (445 aa)
AGRNAgrin. (2044 aa)
THBS3Thrombospondin 3. (956 aa)
PLAUPlasminogen activator, urokinase. (430 aa)
NRXN1Neurexin 1. (1507 aa)
MUC13Mucin 13, cell surface associated. (495 aa)
MEP1BMeprin A subunit. (701 aa)
NPNTNephronectin. (610 aa)
CNTNAP1Contactin associated protein 1. (1364 aa)
DLL3Delta like canonical Notch ligand 3. (618 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (632 aa)
MALRD1MAM and LDL receptor class A domain containing 1. (2163 aa)
NOTCH3Notch receptor 3. (2300 aa)
FAT2FAT atypical cadherin 2. (4349 aa)
EDIL3EGF like repeats and discoidin domains 3. (480 aa)
NELL2Neural EGFL like 2. (816 aa)
NTNG2Netrin G2. (530 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ADAM28Disintegrin and metalloproteinase domain-containing protein 28; May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation. (790 aa)
UMODL1Uromodulin like 1. (1492 aa)
FBN1Fibrillin 1. (2871 aa)
NRG3Neuregulin 3. (681 aa)
LRP1LDL receptor related protein 1. (4544 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1821 aa)
ADGRE1Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (777 aa)
BTCBetacellulin. (178 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
NOTCH1Notch receptor 1. (2556 aa)
FAT4FAT atypical cadherin 4. (4983 aa)
HYAL2Hyaluronidase. (473 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ENSMFAP00000012945Uncharacterized protein. (732 aa)
NID1Nidogen 1. (1247 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (993 aa)
VASNVasorin. (673 aa)
ENSMFAP00000012280Uncharacterized protein. (469 aa)
VWA2Von Willebrand factor A domain containing 2. (781 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (284 aa)
NAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (515 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1041 aa)
LOC101865400Uncharacterized protein. (742 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
LOC102128314VWFA domain-containing protein. (346 aa)
MSANTD3-TMEFF1MSANTD3-TMEFF1 readthrough. (454 aa)
LOC102138242Uncharacterized protein. (455 aa)
CNTNAP3BUncharacterized protein. (1020 aa)
BCANBrevican. (910 aa)
EREGEpiregulin. (169 aa)
SLIT3Slit guidance ligand 3. (1480 aa)
CRELD1Cysteine rich with EGF like domains 1. (422 aa)
ADAM22ADAM metallopeptidase domain 22. (935 aa)
NOTCH2Notch receptor 2. (2610 aa)
SELESelectin E. (612 aa)
ENSMFAP00000008086Uncharacterized protein. (466 aa)
AREGAmphiregulin. (274 aa)
PAMR1Peptidase domain containing associated with muscle regeneration 1; Belongs to the peptidase S1 family. (737 aa)
RELNReelin. (3464 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
ATRNAttractin. (1430 aa)
HEG1Heart development protein with EGF like domains 1. (1285 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (182 aa)
HGFACHGF activator. (657 aa)
TNXBUncharacterized protein. (4244 aa)
NRG1Neuregulin 1. (713 aa)
TMEM8BTransmembrane protein 8B. (472 aa)
TNCTenascin C. (2205 aa)
CNTNAP4Uncharacterized protein. (1308 aa)
MMRN1Multimerin 1. (1223 aa)
MUC4Uncharacterized protein. (957 aa)
SNED1Sushi, nidogen and EGF like domains 1. (1413 aa)
PGAP6Transmembrane protein 8A. (730 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (1017 aa)
TENM3Teneurin transmembrane protein 3. (2699 aa)
DLK2Delta like non-canonical Notch ligand 2. (383 aa)
VWDEVon Willebrand factor D and EGF domains. (1590 aa)
FBN3Fibrillin 3. (2809 aa)
NTNG1Netrin G1. (539 aa)
ITGBL1Integrin subunit beta like 1. (494 aa)
BRINP2BMP/retinoic acid inducible neural specific 2. (783 aa)
CSPG5Uncharacterized protein. (502 aa)
MEP1AMeprin A subunit. (746 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (766 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
DLK1Delta like non-canonical Notch ligand 1. (383 aa)
MEGF11Multiple EGF like domains 11. (1140 aa)
CCBE1Collagen and calcium binding EGF domains 1. (406 aa)
HMCN1Hemicentin 1. (5635 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2855 aa)
SELPSelectin P. (830 aa)
NID2Nidogen 2. (1376 aa)
ZANZonadhesin (gene/pseudogene). (2720 aa)
NRG4Neuregulin 4. (115 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
THBS2Thrombospondin 2. (1172 aa)
MATN3Matrilin 3. (445 aa)
CD248CD248 molecule. (757 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3228 aa)
NCANNeurocan. (1320 aa)
GAS6Growth arrest specific 6. (657 aa)
HYAL3Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Belongs to the glycosyl hydrolase 56 family. (417 aa)
CD93CD93 molecule. (651 aa)
F10Coagulation factor X. (488 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
MEGF8Multiple EGF like domains 8. (2840 aa)
ENSMFAP00000025099Uncharacterized protein. (1153 aa)
ADAM15ADAM metallopeptidase domain 15. (863 aa)
ADAM33ADAM metallopeptidase domain 33. (798 aa)
MEGF10Multiple EGF like domains 10. (1137 aa)
EGFL7EGF like domain multiple 7. (273 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (710 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
LOC102123198Uncharacterized protein. (736 aa)
FAT3FAT atypical cadherin 3. (4624 aa)
NELL1Neural EGFL like 1. (838 aa)
TECTAUncharacterized protein. (1216 aa)
SUSD1Sushi domain containing 1. (760 aa)
ADAM11ADAM metallopeptidase domain 11. (774 aa)
PROS1Protein S. (676 aa)
F7Coagulation factor VII. (472 aa)
THBS4Thrombospondin 4. (961 aa)
IMPG1Interphotoreceptor matrix proteoglycan 1. (797 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
NOTCH4Notch receptor 4. (2000 aa)
THBS1Thrombospondin 1. (1173 aa)
EPGNEpithelial mitogen. (154 aa)
OIT3Oncoprotein induced transcript 3. (545 aa)
ADGRL4Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (690 aa)
VCANVersican. (3398 aa)
F12Coagulation factor XII. (615 aa)
VLDLRVery low density lipoprotein receptor. (947 aa)
MUC3AUncharacterized protein. (4753 aa)
EYSProtein eyes shut homolog; Required to maintain the integrity of photoreceptor cells (By similarity). Specifically required for normal morphology of the photoreceptor ciliary pocket, and might thus facilitate protein trafficking between the photoreceptor inner and outer segments via the transition zone (By similarity). (3165 aa)
SCARF1Scavenger receptor class F member 1. (830 aa)
MATN1Matrilin 1. (495 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
NRXN3Neurexin 3. (1664 aa)
SORL1Sortilin related receptor 1. (2212 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1624 aa)
LRP8LDL receptor related protein 8. (971 aa)
RSPO3R-spondin 3. (293 aa)
CUBNCubilin. (3624 aa)
HSPG2Heparan sulfate proteoglycan 2. (4391 aa)
ADAM23ADAM metallopeptidase domain 23. (852 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1683 aa)
ENSMFAP00000026040EGF-like domain-containing protein. (224 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (462 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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