STRINGSTRING
CCND3 CCND3 CCNT2 CCNT2 CCNE2 CCNE2 CCND1 CCND1 CCNB2 CCNB2 CCND2 CCND2 CCNY CCNY CCNJL CCNJL CCNI CCNI BRF1 BRF1 CCNYL1 CCNYL1 GTF2B GTF2B RB1 RB1 CCNH CCNH CCNL2 CCNL2 CABLES2 CABLES2 ENSMFAP00000013160 ENSMFAP00000013160 CCNL1 CCNL1 RBL1 RBL1 CCNC CCNC ENSMFAP00000015942 ENSMFAP00000015942 CCNO CCNO CABLES1 CABLES1 CCNK CCNK CCNB3 CCNB3 CCNG1 CCNG1 CCNA1 CCNA1 CCNQ CCNQ CNTD2 CNTD2 BRF2 BRF2 CCNYL2 CCNYL2 CCNT1 CCNT1 CCNG2 CCNG2 CCNA2 CCNA2 CCNJ CCNJ CCNE1 CCNE1 RBL2 RBL2 CCNI2 CCNI2 CCNF CCNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (760 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
CCNB2G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition. (398 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
CCNYCyclin Y; Belongs to the cyclin family. (354 aa)
CCNJLCyclin J like; Belongs to the cyclin family. (433 aa)
CCNICyclin I; Belongs to the cyclin family. (377 aa)
BRF1BRF1 RNA polymerase III transcription initiation factor subunit. (677 aa)
CCNYL1Cyclin Y like 1; Belongs to the cyclin family. (359 aa)
GTF2BTranscription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...] (316 aa)
RB1RB transcriptional corepressor 1. (928 aa)
CCNHCyclin-H; Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout t [...] (325 aa)
CCNL2Cyclin L2; Belongs to the cyclin family. (520 aa)
CABLES2Cdk5 and Abl enzyme substrate 2. (477 aa)
ENSMFAP00000013160CYCLIN domain-containing protein; Belongs to the cyclin family. (258 aa)
CCNL1Cyclin L1; Belongs to the cyclin family. (526 aa)
RBL1RB transcriptional corepressor like 1. (1067 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
ENSMFAP00000015942Cyclin N-terminal domain-containing protein. (311 aa)
CCNOCyclin O; Belongs to the cyclin family. (350 aa)
CABLES1Cyclin N-terminal domain-containing protein. (306 aa)
CCNKCyclin K; Belongs to the cyclin family. (596 aa)
CCNB3Cyclin B3; Belongs to the cyclin family. (1363 aa)
CCNG1Cyclin G1; Belongs to the cyclin family. (295 aa)
CCNA1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (465 aa)
CCNQCyclin Q; Belongs to the cyclin family. (248 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (304 aa)
BRF2Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. (419 aa)
CCNYL2Cyclin-Y-like protein 2; Belongs to the cyclin family. Cyclin Y subfamily. (360 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (344 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
CCNJCyclin J; Belongs to the cyclin family. (383 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
RBL2RB transcriptional corepressor like 2. (1141 aa)
CCNI2Cyclin I family member 2; Belongs to the cyclin family. (384 aa)
CCNFCyclin F; Belongs to the cyclin family. (786 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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