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| | PDGFD | Platelet derived growth factor D. (370 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (810 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | CSF1 | Colony stimulating factor 1. (587 aa) |
| | GRB2 | Growth factor receptor-binding protein 2. (217 aa) |
| | PLA2G12A | Phospholipase A2 group XIIA. (189 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | RHOA | Uncharacterized protein. (141 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | PLA2G2E | Phospholipase A(2). (142 aa) |
| | ABL2 | Tyrosine-protein kinase. (1182 aa) |
| | ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (474 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | RALA | RAS like proto-oncogene A. (206 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | LOC102145495 | Ras-GEF domain-containing protein. (536 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) |
| | RAB5A | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] (215 aa) |
| | RAPGEF5 | Rap guanine nucleotide exchange factor 5. (883 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1591 aa) |
| | ENSMFAP00000006047 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | CALM3 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1072 aa) |
| | CALML4 | Calmodulin like 4. (193 aa) |
| | SYNGAP1 | Synaptic Ras GTPase activating protein 1. (1343 aa) |
| | EFNA4 | Ephrin A4; Belongs to the ephrin family. (201 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | HTR7 | 5-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (480 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | LOC102115767 | Ras-GEF domain-containing protein. (590 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) |
| | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1. (1273 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa) |
| | RAC3 | Rac family small GTPase 3. (180 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | ENSMFAP00000011401 | ETS domain-containing protein. (426 aa) |
| | RASAL1 | RAS protein activator like 1. (806 aa) |
| | RASGRP2 | RAS guanyl releasing protein 2. (609 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (2303 aa) |
| | NTF4 | Neurotrophin 4; Belongs to the NGF-beta family. (210 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (600 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1404 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (278 aa) |
| | RRAS | RAS related. (218 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | RAB5B | Uncharacterized protein. (221 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | RALBP1 | RalA binding protein 1. (655 aa) |
| | PRKACG | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (333 aa) |
| | STK4 | Serine/threonine kinase 4. (487 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (842 aa) |
| | RASA2 | RAS p21 protein activator 2. (860 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (816 aa) |
| | IGF1 | Insulin like growth factor 1. (159 aa) |
| | PLA2G3 | Phospholipase A2 group III. (509 aa) |
| | FLT3LG | Fms related tyrosine kinase 3 ligand. (236 aa) |
| | GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (960 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (645 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | ENSMFAP00000017798 | Ras-GEF domain-containing protein. (400 aa) |
| | RGL1 | Ral guanine nucleotide dissociation stimulator like 1. (803 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | PLAAT3 | Phospholipase A and acyltransferase 3. (162 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (808 aa) |
| | CDC42 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (191 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | RASSF1 | Ras association domain family member 1. (340 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (802 aa) |
| | RASAL2 | RAS protein activator like 2. (1280 aa) |
| | PAK6 | Non-specific serine/threonine protein kinase. (681 aa) |
| | PLA2G5 | Phospholipase A(2). (138 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (544 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | PLA2G4B | Phospholipase A2. (781 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | PLA2G12B | Phospholipase A2 group XIIB. (195 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | KSR2 | Kinase suppressor of ras 2. (950 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | RASGRP4 | RAS guanyl releasing protein 4. (673 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | FOXO4 | Forkhead box O4. (505 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | RALGDS | Uncharacterized protein. (902 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | GAB1 | GRB2 associated binding protein 1. (751 aa) |
| | NGFR | Nerve growth factor receptor. (427 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | PLA1A | Phospholipase A1 member A. (456 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | IGF2 | Insulin like growth factor 2. (183 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (280 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1028 aa) |
| | TGFA | Transforming growth factor alpha. (166 aa) |
| | TEK | TEK receptor tyrosine kinase. (1124 aa) |
| | SHC1 | SHC adaptor protein 1. (584 aa) |
| | PLA2G2C | Phospholipase A(2). (151 aa) |
| | EPHA2 | Ephrin type-A receptor 2; Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin- A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DS [...] (1036 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (838 aa) |
| | RASGRP3 | RAS guanyl releasing protein 3. (734 aa) |
| | PLA2G1B | Phospholipase A(2). (148 aa) |
| | EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (924 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | RASAL3 | RAS protein activator like 3. (1011 aa) |
| | PLA2G4E | Phospholipase A2. (869 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | ANGPT1 | Angiopoietin 1. (498 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) |
| | ANGPT4 | Angiopoietin 4. (503 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (322 aa) |
| | LOC102116894 | Ras-GEF domain-containing protein. (469 aa) |
| | RASSF5 | Ras association domain family member 5. (418 aa) |
| | EFNA3 | Ephrin A3; Belongs to the ephrin family. (240 aa) |
| | ETS2 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (398 aa) |
| | PRKCG | Protein kinase C gamma type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing p [...] (698 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | NRAS | Uncharacterized protein. (189 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa) |
| | PLA2G10 | Phospholipase A(2). (165 aa) |
| | PLA2G2D | Phospholipase A(2). (161 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | PLD1 | Phospholipase. (1074 aa) |
| | RASGRF2 | Ras protein specific guanine nucleotide releasing factor 2. (1237 aa) |
| | PLD2 | Phospholipase. (933 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (545 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | GAB2 | GRB2 associated binding protein 2. (677 aa) |
| | ENSMFAP00000034139 | Ras-GEF domain-containing protein. (525 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa) |
| | GNB5 | G protein subunit beta 5. (409 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (312 aa) |
| | RRAS2 | RAS related 2. (204 aa) |
| | PLA2G4D | Phospholipase A2. (817 aa) |
| | EFNA2 | Ephrin A2; Belongs to the ephrin family. (181 aa) |
| | NGF | Nerve growth factor; Belongs to the NGF-beta family. (123 aa) |
| | RAP1A | RAP1A, member of RAS oncogene family. (184 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (991 aa) |
| | PIK3R2 | Uncharacterized protein. (694 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (820 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa) |
| | RASA1 | RAS p21 protein activator 1. (1044 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | ZAP70 | Tyrosine-protein kinase. (619 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1382 aa) |
| | PLA2G4F | Phospholipase A2. (849 aa) |
| | RALB | Ras-related protein Ral-B; Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles (By similarity). Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells (By similarity). Required for suppression of apoptosis (By s [...] (212 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | REL | REL proto-oncogene, NF-kB subunit. (616 aa) |
| | SHOC2 | SHOC2 leucine rich repeat scaffold protein. (582 aa) |
| | PAK5 | Non-specific serine/threonine protein kinase. (719 aa) |
| | RAP1B | Ras-related protein Rap-1b; GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. (184 aa) |
| | SHC2 | Uncharacterized protein. (516 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | NF1 | Neurofibromin 1. (2849 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | PLA2G6 | Phospholipase A2 group VI. (806 aa) |
| | PLA2G2A | Phospholipase A(2). (144 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | ENSMFAP00000041150 | Ras-GEF domain-containing protein. (525 aa) |
| | SHC3 | SHC adaptor protein 3. (598 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | GNG10 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | PLA2G2F | Phospholipase A(2). (199 aa) |
| | ELK1 | ETS domain-containing protein Elk-1. (428 aa) |
| | MRAS | Uncharacterized protein. (208 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | BRAP | BRCA1 associated protein. (592 aa) |
| | RIN1 | Ras and Rab interactor 1. (783 aa) |
| | PAK3 | P21 (RAC1) activated kinase 3. (580 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | RGL2 | Ral guanine nucleotide dissociation stimulator like 2. (777 aa) |
| | RAB5C | RAB5C, member RAS oncogene family. (249 aa) |
| | ENSMFAP00000044716 | Ras-GEF domain-containing protein. (527 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa) |
| | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase. (901 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | RASA3 | RAS p21 protein activator 3. (834 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
