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| | IL10RB | Interleukin 10 receptor subunit beta. (313 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | TNFRSF4 | TNF receptor superfamily member 4. (277 aa) |
| | CCL18 | C-C motif chemokine. (88 aa) |
| | IL22RA1 | Interleukin 22 receptor subunit alpha 1. (574 aa) |
| | IL23A | Interleukin 23 p19 subunit. (189 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) |
| | CSF1 | Colony stimulating factor 1. (587 aa) |
| | TNFRSF9 | TNF receptor superfamily member 9. (254 aa) |
| | ENSMFAP00000001417 | C-C motif chemokine. (84 aa) |
| | IL6ST | Interleukin 6 signal transducer. (942 aa) |
| | IL7R | Interleukin-7 receptor subunit alpha; Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP) (By similarity); Belongs to the type I cytokine receptor family. Type 4 subfamily. (459 aa) |
| | CCR2 | C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | CCL25 | C-C motif chemokine ligand 25. (165 aa) |
| | IL17A | Interleukin 17A. (155 aa) |
| | LTB | Lymphotoxin beta; Belongs to the tumor necrosis factor family. (244 aa) |
| | TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (213 aa) |
| | GDF9 | Growth differentiation factor 9. (455 aa) |
| | IL17RB | Interleukin 17 receptor B. (502 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | CSF3 | Colony stimulating factor 3. (207 aa) |
| | IFNGR2 | Interferon gamma receptor 2. (336 aa) |
| | CCR9 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (369 aa) |
| | LOC102141352 | Uncharacterized protein. (198 aa) |
| | TNFSF12 | TNF superfamily member 12; Belongs to the tumor necrosis factor family. (250 aa) |
| | TNFRSF10B | TNF receptor superfamily member 10b. (445 aa) |
| | TSLP | Thymic stromal lymphopoietin. (159 aa) |
| | IL25 | Interleukin 25. (160 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (281 aa) |
| | IL2RB | Interleukin-2 receptor subunit beta; Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity). (551 aa) |
| | INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa) |
| | IFNLR1 | Interferon lambda receptor 1. (525 aa) |
| | CCL11 | C-C motif chemokine. (97 aa) |
| | IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | CXCL2 | C-X-C motif chemokine. (107 aa) |
| | GDF7 | Growth differentiation factor 7. (450 aa) |
| | IL13RA1 | Interleukin 13 receptor subunit alpha 1. (425 aa) |
| | CCL3 | C-C motif chemokine. (92 aa) |
| | BMP6 | Bone morphogenetic protein 6. (509 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | IL21R | Interleukin 21 receptor. (538 aa) |
| | LOC102141744 | Uncharacterized protein. (198 aa) |
| | LEPR | Leptin receptor. (1163 aa) |
| | CCR10 | C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | IL24 | Interleukin 24. (207 aa) |
| | ENSMFAP00000009740 | Uncharacterized protein. (117 aa) |
| | IL27 | Interleukin 27. (191 aa) |
| | IL34 | Interleukin 34. (242 aa) |
| | LIF | LIF interleukin 6 family cytokine. (202 aa) |
| | CXCL3 | C-X-C motif chemokine. (107 aa) |
| | TNFSF18 | TNF superfamily member 18. (199 aa) |
| | IL5RA | Interleukin 5 receptor alpha. (420 aa) |
| | XCR1 | X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa) |
| | TNFRSF17 | TNF receptor superfamily member 17. (183 aa) |
| | LOC102119743 | C-C motif chemokine. (92 aa) |
| | IL1RL1 | Interleukin 1 receptor like 1. (556 aa) |
| | TNFRSF19 | TNF receptor superfamily member 19. (423 aa) |
| | GHV | Uncharacterized protein. (217 aa) |
| | OSMR | Oncostatin M receptor. (977 aa) |
| | LOC102140303 | Uncharacterized protein. (190 aa) |
| | MPL | MPL proto-oncogene, thrombopoietin receptor. (646 aa) |
| | CCR4 | C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | IFNA6 | Interferon alpha 6. (190 aa) |
| | TNFRSF10A | TNF receptor superfamily member 10a. (311 aa) |
| | CSF2 | Colony stimulating factor 2. (144 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | LOC102136805 | C-C motif chemokine. (92 aa) |
| | MSTN | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (376 aa) |
| | IFNB1 | Interferon beta; Has antiviral, antibacterial and anticancer activities. (187 aa) |
| | LOC102146717 | Uncharacterized protein. (189 aa) |
| | ACKR3 | Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | TNFRSF10D | TNF receptor superfamily member 10d. (382 aa) |
| | IL11 | Interleukin-11; Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation. Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. (140 aa) |
| | IL17B | Interleukin 17B. (180 aa) |
| | ACKR4 | Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa) |
| | IL1F10 | Interleukin-1. (152 aa) |
| | IL20RA | Interleukin 20 receptor subunit alpha. (555 aa) |
| | IL36A | Interleukin-1. (188 aa) |
| | IL13 | Interleukin 13. (146 aa) |
| | CXCL16 | C-X-C motif chemokine ligand 16. (275 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | CXCR3 | C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa) |
| | IL36B | Uncharacterized protein. (164 aa) |
| | IL1RN | Interleukin-1 receptor antagonist protein; Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity (By similarity). Belongs to the IL-1 family. (179 aa) |
| | PPBP | C-X-C motif chemokine. (128 aa) |
| | IL17RC | Interleukin 17 receptor C. (716 aa) |
| | CCL17 | C-C motif chemokine. (91 aa) |
| | CCL26 | C-C motif chemokine. (94 aa) |
| | IL36RN | Interleukin-1. (155 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (397 aa) |
| | LTA | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa) |
| | IL31RA | Interleukin 31 receptor A. (764 aa) |
| | IL2RA | Interleukin 2 receptor alpha. (272 aa) |
| | CCL7 | C-C motif chemokine. (109 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa) |
| | CCR7 | C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | IL16 | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). (1331 aa) |
| | GDF2 | Growth differentiation factor 2. (429 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | PF4 | C-X-C motif chemokine. (101 aa) |
| | TNFRSF13C | TNF receptor superfamily member 13C. (184 aa) |
| | INHBC | Inhibin subunit beta C. (352 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) |
| | CSF3R | Colony stimulating factor 3 receptor. (836 aa) |
| | TNFSF13B | TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (540 aa) |
| | LOC102117861 | C-C motif chemokine. (92 aa) |
| | TNFSF8 | TNF superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa) |
| | BMP3 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa) |
| | CXCL13 | C-X-C motif chemokine. (109 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) |
| | RELT | Tumor necrosis factor receptor superfamily member 19L; May play a role in apoptosis. Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed. Involved in dental enamel formation; Belongs to the RELT family. (440 aa) |
| | IL4R | Interleukin 4 receptor. (825 aa) |
| | CD40 | CD40 molecule. (278 aa) |
| | LOC102134112 | C-C motif chemokine. (111 aa) |
| | GDF1 | TGF_BETA_2 domain-containing protein. (370 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (615 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa) |
| | INHBE | Inhibin subunit beta E. (351 aa) |
| | IL1A | Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity). (271 aa) |
| | LOC102118339 | C-X-C motif chemokine. (112 aa) |
| | INHBB | Inhibin subunit beta B. (360 aa) |
| | IL18RAP | Interleukin 18 receptor accessory protein. (598 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa) |
| | LOC102138968 | Uncharacterized protein. (200 aa) |
| | LOC102137836 | Uncharacterized protein. (200 aa) |
| | TNFRSF1B | TNF receptor superfamily member 1B. (463 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | CD27 | CD27 molecule. (260 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (369 aa) |
| | LTBR | Lymphotoxin beta receptor. (435 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (477 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa) |
| | TNFRSF21 | TNF receptor superfamily member 21. (655 aa) |
| | CCL2 | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] (99 aa) |
| | NGFR | Nerve growth factor receptor. (427 aa) |
| | CX3CR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (386 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | BMP2 | Bone morphogenetic protein 2. (544 aa) |
| | CSF2RB | Colony stimulating factor 2 receptor beta common subunit. (897 aa) |
| | GALT | Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (783 aa) |
| | THPO | Thrombopoietin. (353 aa) |
| | CCL20 | C-C motif chemokine. (96 aa) |
| | EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. (193 aa) |
| | IL12RB2 | Interleukin 12 receptor subunit beta 2. (863 aa) |
| | TNFRSF13B | TNF receptor superfamily member 13B. (293 aa) |
| | IL37 | Interleukin-1. (226 aa) |
| | OSM | Oncostatin M. (252 aa) |
| | XCL1 | SCY domain-containing protein. (114 aa) |
| | IL17F | Interleukin 17F. (163 aa) |
| | IFNE | Interferon epsilon. (194 aa) |
| | CXCL3-2 | C-X-C motif chemokine. (107 aa) |
| | CXCL6 | C-X-C motif chemokine. (124 aa) |
| | CXCL17 | C-X-C motif chemokine ligand 17. (119 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa) |
| | LOC102118223 | C-C motif chemokine. (93 aa) |
| | IL15RA | Interleukin 15 receptor subunit alpha. (253 aa) |
| | CXCL11 | C-X-C motif chemokine. (96 aa) |
| | IL20RB | Interleukin 20 receptor subunit beta. (311 aa) |
| | TNFRSF12A | Uncharacterized protein. (227 aa) |
| | TNFRSF8 | TNF receptor superfamily member 8. (505 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | CCL24 | C-C motif chemokine ligand 24. (119 aa) |
| | CCL8 | C-C motif chemokine. (99 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (662 aa) |
| | EDA | Ectodysplasin A; Belongs to the tumor necrosis factor family. (391 aa) |
| | IL36G | Interleukin-1. (168 aa) |
| | TNFRSF1A | Uncharacterized protein. (455 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (488 aa) |
| | ACVR1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa) |
| | TNFRSF14 | TNF receptor superfamily member 14. (280 aa) |
| | GDF10 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa) |
| | IL19 | Interleukin 19. (214 aa) |
| | IL33 | Interleukin 33. (270 aa) |
| | GDF5 | Growth differentiation factor 5. (499 aa) |
| | CXCR4 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (408 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | CCR3 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (376 aa) |
| | TNFRSF11B | TNF receptor superfamily member 11b. (428 aa) |
| | CCR5 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (379 aa) |
| | CCL13 | C-C motif chemokine. (98 aa) |
| | LOC102124330 | C-X-C motif chemokine. (114 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. (153 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) |
| | IL7 | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (177 aa) |
| | TNFSF9 | TNF superfamily member 9; Belongs to the tumor necrosis factor family. (251 aa) |
| | CCL27 | C-C motif chemokine ligand 27. (112 aa) |
| | ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa) |
| | IL23R | Interleukin 23 receptor. (629 aa) |
| | CCL23 | C-C motif chemokine. (120 aa) |
| | GDF15 | Growth/differentiation factor 15; Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions. On hepatocytes, inhibits growth hormone signaling (By similarity). (308 aa) |
| | TNFSF14 | Tumor necrosis factor ligand superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa) |
| | PF4V1 | C-X-C motif chemokine. (101 aa) |
| | AMH | Anti-Mullerian hormone. (562 aa) |
| | IL13RA2 | Interleukin 13 receptor subunit alpha 2. (388 aa) |
| | IFNGR1 | Uncharacterized protein. (488 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | NGF | Nerve growth factor; Belongs to the NGF-beta family. (123 aa) |
| | IL31 | Interleukin 31. (163 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | TNFRSF6B | TNF receptor superfamily member 6b. (300 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (991 aa) |
| | IL17RA | Interleukin 17 receptor A. (865 aa) |
| | IL17RE | Interleukin 17 receptor E. (698 aa) |
| | GHR | Growth hormone receptor. (645 aa) |
| | CNTFR | Ciliary neurotrophic factor receptor. (372 aa) |
| | IL22 | Interleukin 22. (179 aa) |
| | IL9 | Interleukin 9. (145 aa) |
| | TNFRSF25 | TNF receptor superfamily member 25. (420 aa) |
| | CXCL1L | C-X-C motif chemokine. (154 aa) |
| | IL10RA | Interleukin 10 receptor subunit alpha. (576 aa) |
| | IL27RA | Interleukin 27 receptor subunit alpha. (636 aa) |
| | INHBA | Inhibin subunit beta A. (426 aa) |
| | EPOR | Erythropoietin receptor; Receptor for erythropoietin. (508 aa) |
| | CXCL10 | C-X-C motif chemokine. (98 aa) |
| | LIFR | LIF receptor subunit alpha. (1097 aa) |
| | IL6R | Interleukin 6 receptor. (468 aa) |
| | BMP10 | Bone morphogenetic protein 10. (424 aa) |
| | CCL28 | C-C motif chemokine. (127 aa) |
| | TNFRSF18 | TNF receptor superfamily member 18. (241 aa) |
| | CXCR5 | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | CCL1 | C-C motif chemokine. (96 aa) |
| | IL3 | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (151 aa) |
| | IL1R2 | Interleukin 1 receptor type 2. (398 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (595 aa) |
| | CD70 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (316 aa) |
| | ACVR2B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa) |
| | CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa) |
| | CCL19 | C-C motif chemokine. (123 aa) |
| | NODAL | Nodal growth differentiation factor. (347 aa) |
| | CLCF1 | Cardiotrophin like cytokine factor 1. (225 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | PRLR | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa) |
| | CCR6 | C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | CXCL9 | C-X-C motif chemokine ligand 9. (125 aa) |
| | IFNL1 | Interferon lambda 1. (202 aa) |
| | GDF3 | Growth differentiation factor 3. (364 aa) |
| | IL17C | Interleukin 17C. (197 aa) |
| | CCL22 | C-C motif chemokine ligand 22. (93 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) |
| | IFNAR2 | Uncharacterized protein. (735 aa) |
| | CXCL1 | C-X-C motif chemokine. (107 aa) |
| | IL1RAP | Interleukin 1 receptor accessory protein. (687 aa) |
| | GDF11 | Growth differentiation factor 11. (342 aa) |
| | GDF6 | Growth differentiation factor 6. (455 aa) |
| | IL9R | Interleukin 9 receptor. (514 aa) |
| | CTF1 | Cardiotrophin 1. (201 aa) |
| | LOC102118445 | Uncharacterized protein. (202 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (212 aa) |
| | CCL21 | SCY domain-containing protein. (131 aa) |
| | CXCR6 | C-X-C chemokine receptor type 6; Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. (383 aa) |
| | BMP15 | Bone morphogenetic protein 15. (393 aa) |
| | PRL | Prolactin. (227 aa) |
