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| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | FOXO3 | Forkhead box O3. (672 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | CCNB2 | G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition. (398 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (382 aa) |
| | HLA-F | Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (443 aa) |
| | E2F4 | E2F transcription factor 4. (416 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1196 aa) |
| | CAPN1 | Calpain-1 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction; Belongs to the peptidase C2 family. (732 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) |
| | IGFBP3 | Insulin like growth factor binding protein 3. (291 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | LOC102125623 | Ig-like domain-containing protein; Belongs to the MHC class I family. (389 aa) |
| | PPID | Uncharacterized protein. (370 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (366 aa) |
| | VDAC1 | Uncharacterized protein. (289 aa) |
| | CALM3 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (417 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1072 aa) |
| | CALML4 | Calmodulin like 4. (193 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (918 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (196 aa) |
| | SLC25A5 | Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1210 aa) |
| | ZFP36L2 | ZFP36 ring finger protein like 2. (492 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | LIN9 | Protein lin-9 homolog; Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition (By similarity). (613 aa) |
| | CHEK1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (488 aa) |
| | RB1 | RB transcriptional corepressor 1. (928 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (438 aa) |
| | BTRC | Uncharacterized protein. (605 aa) |
| | TSC1 | TSC complex subunit 1. (1168 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (280 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (246 aa) |
| | LOC102142638 | Protein kinase domain-containing protein. (297 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (812 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | RRAS | RAS related. (218 aa) |
| | FOXM1 | Forkhead box M1. (770 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (1067 aa) |
| | NBN | Nibrin. (754 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (749 aa) |
| | PPP3R1 | Uncharacterized protein. (189 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | Mafa-B | MHC_I-like_Ag-recog domain-containing protein. (139 aa) |
| | TRPM7 | Transient receptor potential cation channel subfamily M member 7. (1848 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (823 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | MYBL2 | MYB proto-oncogene like 2. (700 aa) |
| | LOC102114865 | Ig-like domain-containing protein; Belongs to the MHC class I family. (244 aa) |
| | SLC25A4 | Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (520 aa) |
| | SQSTM1 | Sequestosome 1. (440 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | GATA4 | GATA binding protein 4. (425 aa) |
| | TSC2 | TSC complex subunit 2. (1807 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (544 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (381 aa) |
| | CCNB3 | Cyclin B3; Belongs to the cyclin family. (1363 aa) |
| | MCU | Mitochondrial calcium uniporter. (351 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | CCNA1 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (465 aa) |
| | IL1A | Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity). (271 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | HIPK4 | Homeodomain-interacting protein kinase 4; Protein kinase that phosphorylates TP53, and thus induces TP53 repression of BIRC5 promoter (By similarity). May act as a corepressor of transcription factors (Potential). (616 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa) |
| | SLC25A6 | Solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | CDKN2A | ANK_REP_REGION domain-containing protein. (160 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1060 aa) |
| | FOXO1 | Forkhead box O1. (655 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | CDC25A | Cell division cycle 25A. (491 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (925 aa) |
| | LOC102123548 | Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | LOC102141835 | Ig-like domain-containing protein; Belongs to the MHC class I family. (362 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | HIPK3 | Homeodomain interacting protein kinase 3. (1215 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (322 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | RASSF5 | Ras association domain family member 5. (418 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
| | NRAS | Uncharacterized protein. (189 aa) |
| | CAPN2 | Calpain-2 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs; Belongs to the peptidase C2 family. (703 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | E2F3 | E2F transcription factor 3. (335 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | RRAS2 | RAS related 2. (204 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | RAD50 | Zinc-hook domain-containing protein. (1312 aa) |
| | PIK3R2 | Uncharacterized protein. (694 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (116 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | SLC25A31 | ADP/ATP translocase 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility (By similarity). (315 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (393 aa) |
| | VDAC2 | Uncharacterized protein. (308 aa) |
| | LOC102132794 | Ig-like domain-containing protein; Belongs to the MHC class I family. (334 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | RAD9A | Cell cycle checkpoint control protein RAD9A; Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN [...] (390 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (542 aa) |
| | MAP2K6 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (334 aa) |
| | MRAS | Uncharacterized protein. (208 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | TRAF3IP2 | TRAF3 interacting protein 2. (572 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1141 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | RBBP4 | WD_REPEATS_REGION domain-containing protein. (425 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | MRE11 | Double-strand break repair protein MRE11; Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restr [...] (707 aa) |
| | CDK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa) |
| | SERPINE1 | Serpin family E member 1; Belongs to the serpin family. (402 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (212 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (118 aa) |
