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| | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa) |
| | GRIA2 | Glutamate receptor 2; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of [...] (883 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) |
| | MAOB | Amine oxidase. (520 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A regulatory subunit A. (589 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (474 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) |
| | GRIA4 | Glutamate receptor 4; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of [...] (902 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (366 aa) |
| | ENSMFAP00000006047 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (585 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa) |
| | CALM3 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | CALML4 | Calmodulin like 4. (193 aa) |
| | ATF6B | Activating transcription factor 6 beta. (708 aa) |
| | CAMK2D | Protein kinase domain-containing protein. (533 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (461 aa) |
| | ARRB2 | Arrestin beta 2. (454 aa) |
| | GNAI1 | G protein subunit alpha i1. (422 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (447 aa) |
| | ENSMFAP00000009633 | Uncharacterized protein. (245 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (438 aa) |
| | CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2277 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | DRD5 | Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (478 aa) |
| | GRIA3 | Glutamate receptor 3; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of [...] (894 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | DRD1 | Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa) |
| | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1150 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | DDC | Uncharacterized protein. (480 aa) |
| | SLC18A1 | Solute carrier family 18 member A1. (525 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | COMT | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (221 aa) |
| | PRKACG | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (333 aa) |
| | KCNJ9 | Potassium voltage-gated channel subfamily J member 9. (397 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (645 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (519 aa) |
| | SLC18A2 | Solute carrier family 18 member A2. (485 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | GNAI2 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. (355 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (520 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | KCNJ3 | Potassium voltage-gated channel subfamily J member 3. (501 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | GRIA1 | Glutamate receptor 1; Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulati [...] (916 aa) |
| | CLOCK | Clock circadian regulator. (850 aa) |
| | DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | GNAS | GNAS complex locus. (1023 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | GNAL | G protein subunit alpha L. (450 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (372 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1247 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (457 aa) |
| | MAOA | Amine oxidase. (359 aa) |
| | PPP1R1B | Protein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa) |
| | KCNJ5 | Potassium voltage-gated channel subfamily J member 5. (432 aa) |
| | TH | Tyrosine hydroxylase. (529 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (398 aa) |
| | PRKCG | Protein kinase C gamma type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing p [...] (698 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa) |
| | ARRB1 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] (473 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa) |
| | ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1241 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | KIF5B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (964 aa) |
| | GNB5 | G protein subunit beta 5. (409 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | GNAQ | G protein subunit alpha q. (359 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | SLC6A3 | Sodium-dependent dopamine transporter; Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals (By similarity); Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily. (620 aa) |
| | CALY | Calcyon neuron specific vesicular protein. (217 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | DRD4 | Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (415 aa) |
| | KIF5C | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (909 aa) |
| | KIF5A | Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa) |
| | GSK3A | Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | LOC102136364 | Uncharacterized protein. (291 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | GNG10 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (301 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa) |
| | ARNTL | Aryl hydrocarbon receptor nuclear translocator like. (626 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | CACNA1A | Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2370 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | KCNJ6 | Potassium voltage-gated channel subfamily J member 6. (423 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
