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| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | KRT28 | Keratin 28; Belongs to the intermediate filament family. (464 aa) |
| | GRB2 | Growth factor receptor-binding protein 2. (217 aa) |
| | GABBR1 | Gamma-aminobutyric acid type B receptor subunit 1. (1011 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | KRT25 | Keratin 25; Belongs to the intermediate filament family. (450 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | CTSD | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (557 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | OPRM1 | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] (455 aa) |
| | CALM3 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1072 aa) |
| | CALML4 | Calmodulin like 4. (193 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | ATF6B | Activating transcription factor 6 beta. (708 aa) |
| | KRT27 | Keratin 27; Belongs to the intermediate filament family. (459 aa) |
| | GRM1 | Glutamate metabotropic receptor 1. (1195 aa) |
| | KRT26 | Keratin 26; Belongs to the intermediate filament family. (468 aa) |
| | GNAI1 | G protein subunit alpha i1. (422 aa) |
| | EBAG9 | Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (258 aa) |
| | ENSMFAP00000009633 | Uncharacterized protein. (245 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) |
| | BCL2 | BCL2 apoptosis regulator. (242 aa) |
| | LOC102128765 | IF rod domain-containing protein; Belongs to the intermediate filament family. (416 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1464 aa) |
| | KRT33B | Keratin 33B; Belongs to the intermediate filament family. (404 aa) |
| | FKBP5 | Peptidylprolyl isomerase. (457 aa) |
| | ENSMFAP00000014199 | HATPase_c domain-containing protein. (307 aa) |
| | ENSMFAP00000014202 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (571 aa) |
| | PRKACG | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (333 aa) |
| | KCNJ9 | Potassium voltage-gated channel subfamily J member 9. (397 aa) |
| | TFF1 | Trefoil factor 1. (84 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (519 aa) |
| | MMP9 | Matrix metallopeptidase 9. (707 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | RARA | Retinoic acid receptor alpha. (462 aa) |
| | KRT13 | IF rod domain-containing protein; Belongs to the intermediate filament family. (450 aa) |
| | KRT15 | Keratin 15; Belongs to the intermediate filament family. (456 aa) |
| | GNAI2 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. (355 aa) |
| | KRT39 | Keratin 39; Belongs to the intermediate filament family. (491 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | KRT14 | Keratin 14; Belongs to the intermediate filament family. (475 aa) |
| | KCNJ3 | Potassium voltage-gated channel subfamily J member 3. (501 aa) |
| | KRT18 | IF rod domain-containing protein; Belongs to the intermediate filament family. (430 aa) |
| | HSPA2 | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (641 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | GNAS | GNAS complex locus. (1023 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (208 aa) |
| | KRT38 | Keratin 38; Belongs to the intermediate filament family. (452 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | KRT9 | Keratin 9; Belongs to the intermediate filament family. (387 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (372 aa) |
| | TGFA | Transforming growth factor alpha. (166 aa) |
| | KRT40 | Keratin 40; Belongs to the intermediate filament family. (431 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1247 aa) |
| | SHC1 | SHC adaptor protein 1. (584 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | SP1 | Sp1 transcription factor. (786 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | KRT32 | Keratin 32; Belongs to the intermediate filament family. (448 aa) |
| | KCNJ5 | Potassium voltage-gated channel subfamily J member 5. (432 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (322 aa) |
| | GABBR2 | Gamma-aminobutyric acid type B receptor subunit 2. (883 aa) |
| | PGR | Progesterone receptor. (936 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa) |
| | KRT33A | Keratin 33A; Belongs to the intermediate filament family. (404 aa) |
| | ESR2 | Estrogen receptor 2. (530 aa) |
| | NRAS | Uncharacterized protein. (189 aa) |
| | HSP90B1 | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family. (804 aa) |
| | NCOA3 | Nuclear receptor coactivator. (1420 aa) |
| | KRT37 | Keratin 37; Belongs to the intermediate filament family. (449 aa) |
| | MMP2 | Matrix metallopeptidase 2. (660 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa) |
| | HSP90AA1 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] (831 aa) |
| | ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1241 aa) |
| | KRT19 | Keratin 19; Belongs to the intermediate filament family. (400 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | KRT12 | Keratin 12; Belongs to the intermediate filament family. (495 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | GNAQ | G protein subunit alpha q. (359 aa) |
| | KRT20 | Keratin 20; Belongs to the intermediate filament family. (424 aa) |
| | PIK3R2 | Uncharacterized protein. (694 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | KRT36 | Keratin 36; Belongs to the intermediate filament family. (467 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1102 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | KRT34 | Keratin 34; Belongs to the intermediate filament family. (436 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | KRT23 | Keratin 23; Belongs to the intermediate filament family. (422 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | LOC102129383 | IF rod domain-containing protein; Belongs to the intermediate filament family. (430 aa) |
| | HSP90AB1 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] (724 aa) |
| | HSPA8 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa) |
| | KRT10 | Keratin 10; Belongs to the intermediate filament family. (566 aa) |
| | SHC2 | Uncharacterized protein. (516 aa) |
| | NCOA1 | Nuclear receptor coactivator 1. (1534 aa) |
| | SHC3 | SHC adaptor protein 3. (598 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (301 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) |
| | KRT16 | Keratin 16; Belongs to the intermediate filament family. (476 aa) |
| | KRT17 | Keratin 17; Belongs to the intermediate filament family. (432 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | KRT24 | Keratin 24; Belongs to the intermediate filament family. (522 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1236 aa) |
| | KCNJ6 | Potassium voltage-gated channel subfamily J member 6. (423 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | HSPA1L | Heat shock 70 kDa protein 1-like; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis an [...] (643 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | FKBP4 | Peptidylprolyl isomerase. (459 aa) |
| | KRT35 | Keratin 35; Belongs to the intermediate filament family. (455 aa) |
| | POMC | Proopiomelanocortin. (265 aa) |
