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PLCB4 PLCB4 ADCY6 ADCY6 CD38 CD38 LOC102123076 LOC102123076 ADCY8 ADCY8 ADCY2 ADCY2 CALM3 CALM3 CALML4 CALML4 ATP2B2 ATP2B2 LYZ LYZ SLC12A2 SLC12A2 LOC102116355 LOC102116355 NOS1 NOS1 ENSMFAP00000009633 ENSMFAP00000009633 PRKACA PRKACA CALML3 CALML3 ATP2B4 ATP2B4 ADRB2 ADRB2 PRKCA PRKCA LYZL1 LYZL1 PRKACG PRKACG ADRA1A ADRA1A PRKCB PRKCB ATP1A4 ATP1A4 VAMP2 VAMP2 ATP2B3 ATP2B3 GUCY1A1 GUCY1A1 FXYD2 FXYD2 AQP5 AQP5 CAMP CAMP ITPR2 ITPR2 CST3 CST3 PLCB1 PLCB1 BST1 BST1 GNAS GNAS PRKACB PRKACB GUCY1B1 GUCY1B1 PLCB3 PLCB3 ADRA1B ADRA1B KCNMA1 KCNMA1 ATP2B1 ATP2B1 ENSMFAP00000028924 ENSMFAP00000028924 PRKG1 PRKG1 CST5 CST5 PRKCG PRKCG ITPR1 ITPR1 PLCB2 PLCB2 SLC4A2 SLC4A2 HTN1 HTN1 ADCY5 ADCY5 ADRA1D ADRA1D GNAQ GNAQ RYR3 RYR3 GUCY1A2 GUCY1A2 LPO LPO ATP1A1 ATP1A1 SLC9A1 SLC9A1 ADCY7 ADCY7 PRKG2 PRKG2 ADCY1 ADCY1 ATP1B3 ATP1B3 KCNN4 KCNN4 ADCY3 ADCY3 MUC7 MUC7 BEST2 BEST2 TRPV6 TRPV6 ITPR3 ITPR3 CALML6 CALML6 ATP1B4 ATP1B4 ADRB3 ADRB3 ATP1B2 ATP1B2 ATP1B1 ATP1B1 ADCY4 ADCY4 ATP1A3 ATP1A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
CD38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system (By similarity). (301 aa)
LOC102123076Alpha-amylase. (514 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
CALML4Calmodulin like 4. (193 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
LYZLysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Belongs to the glycosyl hydrolase 22 family. (148 aa)
SLC12A2Solute carrier family 12 member 2. (1210 aa)
LOC102116355Cystatin domain-containing protein; Belongs to the cystatin family. (141 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
ENSMFAP00000009633Uncharacterized protein. (245 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
ADRB2Adrenergic receptor beta 2. (415 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
LYZL1Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family. (148 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (333 aa)
ADRA1AAdrenoceptor alpha 1A. (462 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (645 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
CAMPCathelicidin antimicrobial peptide; Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity; Belongs to the cathelicidin family. (173 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
CST3Cystatin C; Belongs to the cystatin family. (146 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
BST1ADP-ribosyl cyclase CD157. (315 aa)
GNASGNAS complex locus. (1023 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (642 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1247 aa)
ADRA1BAdrenoceptor alpha 1B. (518 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1285 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
ENSMFAP00000028924Uncharacterized protein. (167 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
CST5Cystatin D; Belongs to the cystatin family. (143 aa)
PRKCGProtein kinase C gamma type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing p [...] (698 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
SLC4A2Anion exchange protein. (1238 aa)
HTN1Uncharacterized protein. (56 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1241 aa)
ADRA1DAdrenoceptor alpha 1D. (462 aa)
GNAQG protein subunit alpha q. (359 aa)
RYR3Ryanodine receptor 3. (4873 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (730 aa)
LPOLactoperoxidase. (712 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1102 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
MUC7Mucin 7, secreted. (447 aa)
BEST2Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (509 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (821 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
CALML6Calmodulin like 6. (181 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
ADRB3Adrenergic receptor beta 3. (418 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (303 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1236 aa)
ATP1A3Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1261 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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