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PLCB4 PLCB4 PLA2G12A PLA2G12A ADCY6 ADCY6 RHOA RHOA PLA2G2E PLA2G2E CLCA1 CLCA1 LOC102127568 LOC102127568 CD38 CD38 LOC102126989 LOC102126989 LOC102123076 LOC102123076 ADCY8 ADCY8 RYR2 RYR2 ADCY2 ADCY2 CLCA2 CLCA2 CPB1 CPB1 RAB3D RAB3D CCK CCK PNLIP PNLIP TPCN2 TPCN2 CFTR CFTR ATP2B2 ATP2B2 SLC12A2 SLC12A2 ATP2A3 ATP2A3 SLC4A4 SLC4A4 LOC102127372 LOC102127372 ENSMFAP00000009633 ENSMFAP00000009633 CELA3B CELA3B ENSMFAP00000011235 ENSMFAP00000011235 ATP2B4 ATP2B4 LOC102147021 LOC102147021 CA2 CA2 PRKCA PRKCA ATP2A2 ATP2A2 PLA2G3 PLA2G3 CLCA4 CLCA4 PRKCB PRKCB ATP1A4 ATP1A4 ATP2B3 ATP2B3 FXYD2 FXYD2 PLA2G5 PLA2G5 ITPR2 ITPR2 PLA2G12B PLA2G12B CELA2B CELA2B PLCB1 PLCB1 BST1 BST1 GNAS GNAS KCNQ1 KCNQ1 PLCB3 PLCB3 PLA2G2C PLA2G2C CPA1 CPA1 KCNMA1 KCNMA1 PLA2G1B PLA2G1B LOC101865639 LOC101865639 ATP2B1 ATP2B1 CEL CEL PRKCG PRKCG ITPR1 ITPR1 CTRB2 CTRB2 PLA2G10 PLA2G10 PLCB2 PLCB2 PLA2G2D PLA2G2D RAB27B RAB27B SLC4A2 SLC4A2 SCTR SCTR ADCY5 ADCY5 CCKAR CCKAR GNAQ GNAQ CPA3 CPA3 CPA2 CPA2 RAP1A RAP1A ATP1A1 ATP1A1 SLC9A1 SLC9A1 ADCY7 ADCY7 ADCY1 ADCY1 ATP1B3 ATP1B3 ADCY3 ADCY3 RAP1B RAP1B PLA2G2A PLA2G2A SLC26A3 SLC26A3 ITPR3 ITPR3 PLA2G2F PLA2G2F ATP1B4 ATP1B4 CPB2 CPB2 ATP1B2 ATP1B2 ATP1B1 ATP1B1 ADCY4 ADCY4 ATP1A3 ATP1A3 RAB11A RAB11A PNLIPRP2 PNLIPRP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
PLA2G12APhospholipase A2 group XIIA. (189 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
RHOAUncharacterized protein. (141 aa)
PLA2G2EPhospholipase A(2). (142 aa)
CLCA1Chloride channel accessory 1. (913 aa)
LOC102127568Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (269 aa)
CD38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system (By similarity). (301 aa)
LOC102126989Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
LOC102123076Alpha-amylase. (514 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
RYR2Ryanodine receptor 2. (4943 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
CLCA2Chloride channel accessory 2. (943 aa)
CPB1Carboxypeptidase B1. (417 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
CCKCholecystokinin-58 desnonopeptide; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Belongs to the gastrin/cholecystokinin family. (115 aa)
PNLIPTriacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
TPCN2Two pore segment channel 2. (752 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1484 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
SLC12A2Solute carrier family 12 member 2. (1210 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1051 aa)
SLC4A4Anion exchange protein. (1100 aa)
LOC102127372Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa)
ENSMFAP00000009633Uncharacterized protein. (245 aa)
CELA3BPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (270 aa)
ENSMFAP00000011235Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (230 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
LOC102147021Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (262 aa)
CA2Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (260 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
CLCA4Chloride channel accessory 4. (917 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (645 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
PLA2G5Phospholipase A(2). (138 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
PLA2G12BPhospholipase A2 group XIIB. (195 aa)
CELA2BChymotrypsin like elastase 2B; Belongs to the peptidase S1 family. (236 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
BST1ADP-ribosyl cyclase CD157. (315 aa)
GNASGNAS complex locus. (1023 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (644 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1247 aa)
PLA2G2CPhospholipase A(2). (151 aa)
CPA1Carboxypeptidase A1. (419 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1285 aa)
PLA2G1BPhospholipase A(2). (148 aa)
LOC101865639Uncharacterized protein. (317 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
CELCarboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. (734 aa)
PRKCGProtein kinase C gamma type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing p [...] (698 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
CTRB2Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
PLA2G10Phospholipase A(2). (165 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
PLA2G2DPhospholipase A(2). (161 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
SLC4A2Anion exchange protein. (1238 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (443 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1241 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
GNAQG protein subunit alpha q. (359 aa)
CPA3Carboxypeptidase A3. (432 aa)
CPA2Carboxypeptidase A2. (421 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1102 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
RAP1BRas-related protein Rap-1b; GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. (184 aa)
PLA2G2APhospholipase A(2). (144 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (761 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
PLA2G2FPhospholipase A(2). (199 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
CPB2Carboxypeptidase B2. (423 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (303 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1236 aa)
ATP1A3Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1261 aa)
RAB11ARAB11A, member RAS oncogene family. (216 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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