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C8B | Complement C8 beta chain. (591 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) | ||||
PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) | ||||
ENSMFAP00000001843 | Ig-like domain-containing protein. (181 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) | ||||
CTSG | Cathepsin G; Belongs to the peptidase S1 family. (255 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
ACTN4 | Actinin alpha 4. (931 aa) | ||||
CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) | ||||
PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa) | ||||
COL4A2 | Collagen type IV alpha 2 chain. (1724 aa) | ||||
LAMB1 | Laminin subunit beta 1. (1810 aa) | ||||
RAB5A | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] (215 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1072 aa) | ||||
CXCL2 | C-X-C motif chemokine. (107 aa) | ||||
COL4A3 | Collagen type IV alpha 3 chain. (1670 aa) | ||||
RAB7A | RAB7A, member RAS oncogene family. (207 aa) | ||||
ITGB2 | Integrin beta. (874 aa) | ||||
C8A | Complement C8 alpha chain. (584 aa) | ||||
LAMC2 | Laminin subunit gamma 2. (1301 aa) | ||||
ARG2 | Arginase. (354 aa) | ||||
ENSMFAP00000009633 | Uncharacterized protein. (245 aa) | ||||
PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) | ||||
CXCL3 | C-X-C motif chemokine. (107 aa) | ||||
LOC102124047 | Ig-like domain-containing protein. (217 aa) | ||||
LOC102139130 | Ig-like domain-containing protein. (118 aa) | ||||
LAMA1 | Laminin subunit alpha 1. (3079 aa) | ||||
LOC102135686 | Ig-like domain-containing protein. (191 aa) | ||||
TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa) | ||||
ENSMFAP00000011903 | Ig-like domain-containing protein. (133 aa) | ||||
CSF2 | Colony stimulating factor 2. (144 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) | ||||
CD14 | Uncharacterized protein. (384 aa) | ||||
PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) | ||||
PRDX1 | Thioredoxin domain-containing protein. (199 aa) | ||||
RAB5B | Uncharacterized protein. (221 aa) | ||||
PRKACG | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (333 aa) | ||||
LAMB2 | Laminin subunit beta 2. (1798 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (645 aa) | ||||
ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1147 aa) | ||||
CD1B | CD1b molecule. (333 aa) | ||||
COL4A5 | Collagen type IV alpha 5 chain. (1691 aa) | ||||
CD1C | CD1c molecule. (332 aa) | ||||
RAB7B | RAB7B, member RAS oncogene family. (189 aa) | ||||
FN1 | Fibronectin 1. (2477 aa) | ||||
NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1218 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) | ||||
COL4A6 | Collagen type IV alpha 6 chain. (1705 aa) | ||||
CD1E | CD1e molecule. (426 aa) | ||||
ENSMFAP00000020718 | Ig-like domain-containing protein. (193 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (544 aa) | ||||
LOC102131730 | SERPIN domain-containing protein; Belongs to the serpin family. (382 aa) | ||||
SERPINB10 | Serpin family B member 10; Belongs to the serpin family. (397 aa) | ||||
GNA14 | G protein subunit alpha 14. (355 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa) | ||||
LOC102135631 | SERPIN domain-containing protein; Belongs to the serpin family. (379 aa) | ||||
PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) | ||||
GNAS | GNAS complex locus. (1023 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa) | ||||
SERPINB6 | Serpin B6; Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress. May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). (395 aa) | ||||
PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) | ||||
CD1D | CD1d molecule. (337 aa) | ||||
GNAL | G protein subunit alpha L. (450 aa) | ||||
LOC102135021 | SERPIN domain-containing protein; Belongs to the serpin family. (390 aa) | ||||
SERPINB13 | Serpin family B member 13; Belongs to the serpin family. (400 aa) | ||||
CD1A | CD1a molecule. (327 aa) | ||||
CXCL3-2 | C-X-C motif chemokine. (107 aa) | ||||
VCL | Uncharacterized protein. (80 aa) | ||||
PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1247 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
HSPB1 | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (205 aa) | ||||
LAMA3 | Laminin subunit alpha 3. (3333 aa) | ||||
ARG1 | Arginase. (322 aa) | ||||
COL1A2 | Collagen type I alpha 2 chain. (1366 aa) | ||||
LOC102118733 | Ig-like domain-containing protein. (192 aa) | ||||
SERPINB9 | Serpin family B member 9; Belongs to the serpin family. (376 aa) | ||||
LAMC3 | Laminin subunit gamma 3. (1070 aa) | ||||
PRKCG | Protein kinase C gamma type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing p [...] (698 aa) | ||||
LAMC1 | Laminin subunit gamma 1. (1608 aa) | ||||
CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. (277 aa) | ||||
LAMA4 | Laminin subunit alpha 4. (1823 aa) | ||||
PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa) | ||||
IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) | ||||
LAMB3 | Laminin subunit beta 3. (1094 aa) | ||||
LAMB4 | Laminin subunit beta 4. (1762 aa) | ||||
ENSMFAP00000033644 | Ig-like domain-containing protein. (192 aa) | ||||
ACTN1 | Alpha-actinin-1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity). (914 aa) | ||||
COL4A1 | Collagen type IV alpha 1 chain. (1607 aa) | ||||
COL3A1 | Collagen type III alpha 1 chain. (1466 aa) | ||||
LOC102128954 | Ig-like domain-containing protein. (191 aa) | ||||
GNAQ | G protein subunit alpha q. (359 aa) | ||||
COL1A1 | Collagen type I alpha 1 chain. (1464 aa) | ||||
ENSMFAP00000035747 | Ig-like domain-containing protein. (198 aa) | ||||
IL1R1 | Interleukin 1 receptor type 1. (569 aa) | ||||
PIK3R2 | Uncharacterized protein. (694 aa) | ||||
CXCL1L | C-X-C motif chemokine. (154 aa) | ||||
ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1102 aa) | ||||
IL1R2 | Interleukin 1 receptor type 2. (398 aa) | ||||
C8G | Complement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (202 aa) | ||||
GNA11 | G protein subunit alpha 11. (359 aa) | ||||
LAMA5 | Laminin subunit alpha 5. (3699 aa) | ||||
TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (836 aa) | ||||
C9 | Complement C9. (561 aa) | ||||
LAMA2 | Laminin subunit alpha 2. (3122 aa) | ||||
CXCL1 | C-X-C motif chemokine. (107 aa) | ||||
RAB5C | RAB5C, member RAS oncogene family. (249 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (212 aa) | ||||
GNA15 | G protein subunit alpha 15. (330 aa) | ||||
COL4A4 | Collagen type IV alpha 4 chain. (1692 aa) |