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| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | CCNT2 | Cyclin T2; Belongs to the cyclin family. (760 aa) |
| | KDM6A | Lysine demethylase 6A. (1450 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | BCL2A1 | BCL2 related protein A1. (175 aa) |
| | LMO2 | LIM domain only 2. (222 aa) |
| | LOC102120735 | KRAB-related domain-containing protein. (188 aa) |
| | ID2 | DNA-binding protein inhibitor ID-2; Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the C [...] (134 aa) |
| | ENSMFAP00000001843 | Ig-like domain-containing protein. (181 aa) |
| | PAX7 | Paired box 7. (503 aa) |
| | ENSMFAP00000002130 | DEFENSIN domain-containing protein. (94 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | ATF1 | Activating transcription factor 1. (270 aa) |
| | FUT8 | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (575 aa) |
| | CD86 | CD86 molecule. (329 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa) |
| | ARNT2 | Aryl hydrocarbon receptor nuclear translocator 2. (717 aa) |
| | IGFBP3 | Insulin like growth factor binding protein 3. (291 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (637 aa) |
| | BAIAP3 | BAI1 associated protein 3. (1152 aa) |
| | RXRG | Retinoid X receptor gamma. (463 aa) |
| | ETV5 | Testis cDNA, clone: QtsA-18044, similar to human ets variant gene 5 (ets-related molecule) (ETV5). (510 aa) |
| | PML | Promyelocytic leukemia. (882 aa) |
| | IL2RB | Interleukin-2 receptor subunit beta; Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity). (551 aa) |
| | MEIS1 | Meis homeobox 1. (465 aa) |
| | MEN1 | Menin 1. (615 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1273 aa) |
| | MLLT3 | MLLT3 super elongation complex subunit. (570 aa) |
| | ETV7 | ETS variant 7. (341 aa) |
| | BCL6 | BCL6 transcription repressor. (708 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | FCGR1A | Uncharacterized protein. (375 aa) |
| | HOXA10 | Homeobox A10. (410 aa) |
| | HIST1H3B | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | LOC102147067 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | LOC102124047 | Ig-like domain-containing protein. (217 aa) |
| | LOC102139130 | Ig-like domain-containing protein. (118 aa) |
| | ENSMFAP00000010627 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) |
| | LOC102135686 | Ig-like domain-containing protein. (191 aa) |
| | GRIA3 | Glutamate receptor 3; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of [...] (894 aa) |
| | LOC102130997 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | ENSMFAP00000011903 | Ig-like domain-containing protein. (133 aa) |
| | SUPT3H | SPT3 homolog, SAGA and STAGA complex component. (328 aa) |
| | ENSMFAP00000012034 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | H3-4 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | ENSMFAP00000012162 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
| | CSF2 | Colony stimulating factor 2. (144 aa) |
| | CD14 | Uncharacterized protein. (384 aa) |
| | PBX3 | PBX homeobox 3. (434 aa) |
| | NUPR1 | Nuclear protein 1, transcriptional regulator. (100 aa) |
| | DDX5 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] (614 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1404 aa) |
| | LOC102146894 | Histone domain-containing protein. (136 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | G8F5U3_MACFA | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | MPO | Myeloperoxidase. (745 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (816 aa) |
| | TLX3 | T cell leukemia homeobox 3. (338 aa) |
| | IGF1 | Insulin like growth factor 1. (159 aa) |
| | WT1 | WT1 transcription factor. (513 aa) |
| | PRCC | Proline rich mitotic checkpoint control factor. (491 aa) |
| | MMP9 | Matrix metallopeptidase 9. (707 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1147 aa) |
| | TRAF1 | TNF receptor-associated factor. (416 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | NSD2 | Nuclear receptor binding SET domain protein 2. (1365 aa) |
| | PTCRA | Pre T cell antigen receptor alpha. (281 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (427 aa) |
| | ERG | ETS transcription factor ERG. (486 aa) |
| | ASPSCR1 | ASPSCR1 tether for SLC2A4, UBX domain containing. (548 aa) |
| | RARA | Retinoic acid receptor alpha. (462 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | PAX3 | Paired box 3. (493 aa) |
| | BCL11B | BAF chromatin remodeling complex subunit BCL11B. (870 aa) |
| | RUNX1T1 | RUNX1 partner transcriptional co-repressor 1. (662 aa) |
| | TCF3 | Transcription factor 3. (654 aa) |
| | SIX1 | SIX homeobox 1. (284 aa) |
| | MYCN | MYCN proto-oncogene, bHLH transcription factor. (464 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | CD40 | CD40 molecule. (278 aa) |
| | LYL1 | LYL1 basic helix-loop-helix family member. (280 aa) |
| | SSX1 | SSX family member 1. (188 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | LOC102126320 | DEFENSIN domain-containing protein. (94 aa) |
| | ENSMFAP00000020718 | Ig-like domain-containing protein. (193 aa) |
| | LOC102116444 | Defensin_propep domain-containing protein; Belongs to the alpha-defensin family. (76 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (544 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (203 aa) |
| | ELK4 | ETS transcription factor ELK4. (431 aa) |
| | LOC102123260 | KRAB-related domain-containing protein. (188 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | H3F3B | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | CCNA1 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (465 aa) |
| | ENSMFAP00000022290 | Histone domain-containing protein. (113 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | GZMB | Granzyme B; Belongs to the peptidase S1 family. (281 aa) |
| | LOC102117659 | DEFENSIN domain-containing protein. (96 aa) |
| | POLK | DNA polymerase kappa. (870 aa) |
| | HMGA2 | High mobility group AT-hook 2. (147 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | PROM1 | Prominin 1. (864 aa) |
| | NGFR | Nerve growth factor receptor. (427 aa) |
| | ENSMFAP00000025317 | Hist_deacetyl domain-containing protein. (258 aa) |
| | PAX5 | Paired box 5. (391 aa) |
| | BMP2K | BMP2 inducible kinase. (1144 aa) |
| | HOXA11 | Homeobox A11. (311 aa) |
| | LOC102121259 | KRAB-related domain-containing protein. (246 aa) |
| | FOXO1 | Forkhead box O1. (655 aa) |
| | ITGB7 | Integrin beta; Belongs to the integrin beta chain family. (798 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (280 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1028 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | TMPRSS2 | Transmembrane serine protease 2; Belongs to the peptidase S1 family. (529 aa) |
| | CDK14 | Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | SP1 | Sp1 transcription factor. (786 aa) |
| | LOC107126396 | KRAB-related domain-containing protein. (188 aa) |
| | SIX4 | SIX homeobox 4. (780 aa) |
| | PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (562 aa) |
| | TAF15 | TATA-box binding protein associated factor 15. (584 aa) |
| | LOC102118733 | Ig-like domain-containing protein. (192 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | CCNT1 | Cyclin T1; Belongs to the cyclin family. (728 aa) |
| | ETV4 | ETS variant 4. (484 aa) |
| | PER2 | Period circadian regulator 2. (1254 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1127 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
| | NFKBIZ | NFKB inhibitor zeta. (719 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | HHEX | Hematopoietically expressed homeobox. (270 aa) |
| | ENSMFAP00000033644 | Ig-like domain-containing protein. (192 aa) |
| | ENSMFAP00000034298 | Histone H3; Belongs to the histone H3 family. (141 aa) |
| | LOC102125546 | DEFENSIN domain-containing protein. (94 aa) |
| | LOC102128954 | Ig-like domain-containing protein. (191 aa) |
| | RXRB | Retinoid X receptor beta. (537 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa) |
| | RUNX2 | RUNX family transcription factor 2. (627 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | ENSMFAP00000035747 | Ig-like domain-containing protein. (198 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (991 aa) |
| | LOC102116064 | Defensin_propep domain-containing protein; Belongs to the alpha-defensin family. (76 aa) |
| | CEBPE | CCAAT/enhancer-binding protein. (281 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2442 aa) |
| | SPINT1 | Uncharacterized protein. (529 aa) |
| | KLF3 | Kruppel like factor 3. (345 aa) |
| | AFF1 | AF4/FMR2 family member 1. (1221 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | ZBTB17 | Zinc finger and BTB domain containing 17. (807 aa) |
| | MMP3 | Matrix metallopeptidase 3. (477 aa) |
| | LOC102119223 | KRAB-related domain-containing protein. (222 aa) |
| | LOC102116821 | Defensin_propep domain-containing protein; Belongs to the alpha-defensin family. (76 aa) |
| | BMI1 | RING-type domain-containing protein. (326 aa) |
| | MITF | Melanocyte inducing transcription factor. (519 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (393 aa) |
| | PLAU | Plasminogen activator, urokinase. (430 aa) |
| | REL | REL proto-oncogene, NF-kB subunit. (616 aa) |
| | TLX1 | T cell leukemia homeobox 1. (330 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (553 aa) |
| | DEFA6 | Defensin alpha 6. (100 aa) |
| | IL3 | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (151 aa) |
| | IL1R2 | Interleukin 1 receptor type 2. (398 aa) |
| | HPGD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4 (By similarity); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa) |
| | LDB1 | LIM domain binding 1. (411 aa) |
| | HOXA9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa) |
| | ELANE | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (264 aa) |
| | FLI1 | Fli-1 proto-oncogene, ETS transcription factor. (453 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | DOT1L | Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1562 aa) |
| | MLLT1 | MLLT1 super elongation complex subunit. (561 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (212 aa) |
| | LOC102125912 | DEFENSIN domain-containing protein. (94 aa) |
| | LOC102118641 | Defensin_propep domain-containing protein. (97 aa) |
| | JMJD1C | Jumonji domain containing 1C. (2536 aa) |
| | PAX8 | Paired box 8. (456 aa) |
| | FEV | FEV transcription factor, ETS family member. (238 aa) |
| | TFE3 | Transcription factor binding to IGHM enhancer 3. (575 aa) |
| | ETV6 | ETS variant 6. (452 aa) |
