88 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASPM	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3476 aa)
	IQCB1	IQ calmodulin-binding motif-containing protein 1 isoform a. (598 aa)
	FOXH1	Forkhead box H1. (352 aa)
	B3GALT5	Hexosyltransferase. (311 aa)
	CLIC5	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (412 aa)
	TYMS	Thymidylate synthetase. (313 aa)
	CD44	Phagocytic glycoprotein I. (742 aa)
	ABCE1	ATP-binding cassette sub-family E member 1. (599 aa)
	SRSF1	Uncharacterized protein. (287 aa)
	LOC706496	Uncharacterized protein. (204 aa)
	ALAS1	5-aminolevulinate synthase. (640 aa)
	KLHL18	Kelch like family member 18. (574 aa)
	ABCB5	ATP binding cassette subfamily B member 5. (1257 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	RPL9	60S ribosomal protein L9. (192 aa)
	F6QKX9_MACMU	Ribosomal_S10 domain-containing protein. (119 aa)
	F6S3I5_MACMU	Transcription factor BTF3; Belongs to the NAC-beta family. (124 aa)
	PTOV1	PTOV1 extended AT-hook containing adaptor protein. (436 aa)
	ANXA2	Annexin. (357 aa)
	LOC712274	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (218 aa)
	KIF18A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (897 aa)
	LOC704249	Phosphoglycerate kinase. (417 aa)
	F6VV14_MACMU	Uncharacterized protein. (242 aa)
	RPS8	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
	F7GUF9_MACMU	Uncharacterized protein; Belongs to the universal ribosomal protein uS8 family. (130 aa)
	UBE2S	Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
	NIP7	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	RPL13	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (211 aa)
	F7HF18_MACMU	Ribosomal_S10 domain-containing protein. (119 aa)
	MRPL49	39S ribosomal protein L49, mitochondrial. (166 aa)
	B3GALT1	Hexosyltransferase. (326 aa)
	BTF3	Transcription factor BTF3; Belongs to the NAC-beta family. (206 aa)
	F7A4F5_MACMU	Uncharacterized protein. (138 aa)
	IGF2BP2	Insulin like growth factor 2 mRNA binding protein 2. (556 aa)
	WWOX	WW domain containing oxidoreductase. (414 aa)
	MYO10	Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2058 aa)
	RPS3	40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	PYGB	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (1186 aa)
	DEAF1	DEAF1 transcription factor. (615 aa)
	LOC709201	Uncharacterized protein. (415 aa)
	F6WSW4_MACMU	Ribosomal_L6 domain-containing protein. (160 aa)
	RUVBL1	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
	SLC11A2	Solute carrier family 11 member 2. (597 aa)
	UMPS	Uridine monophosphate synthetase. (480 aa)
	GOLGA2	Golgin A2. (1021 aa)
	CDC20	Cell division cycle protein 20 homolog. (499 aa)
	PGK1	Phosphoglycerate kinase. (417 aa)
	H9H5Q1_MACMU	Uncharacterized protein. (126 aa)
	ENSMMUP00000041819	Uncharacterized protein. (298 aa)
	NCF2	Neutrophil cytosolic factor 2. (526 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	GTF2I	Uncharacterized protein. (1082 aa)
	SUMO1	Small ubiquitin-related modifier. (101 aa)
	CAD	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2306 aa)
	CARS2	Cysteinyl-tRNA synthetase 2, mitochondrial. (563 aa)
	NDUFB9	NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (179 aa)
	RAP1B	Ras-related protein Rap-1b isoform 1. (184 aa)
	CDH17	Cadherin 17. (832 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (314 aa)
	RPS15A	40S ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family. (130 aa)
	CLDN7	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	SLC25A3	Solute carrier family 25 member 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (417 aa)
	CEACAM1	Uncharacterized protein. (525 aa)
	ENSMMUP00000062885	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (111 aa)
	CTNNB1	Catenin beta-1. (781 aa)
	ITPA	Uncharacterized protein. (229 aa)
	ANXA13	Annexin. (357 aa)
	ASMTL	Dimerisation2 domain-containing protein. (480 aa)
	RPS20	40S ribosomal protein S20 isoform 2. (119 aa)
	LOC693573	Uncharacterized protein. (364 aa)
	LOC106995141	Uncharacterized protein. (621 aa)
	CDK5RAP3	CDK5 regulatory subunit-associated protein 3. (506 aa)
	NOTUM	Notum, palmitoleoyl-protein carboxylesterase. (670 aa)
	CAMLG	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (296 aa)
	RNGTT	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
	TGM2	Protein-glutamine gamma-glutamyltransferase 2 isoform a. (687 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (670 aa)
	ENSMMUP00000074770	Uncharacterized protein. (197 aa)
	RPS29	Uncharacterized protein. (99 aa)
	RPL3	Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family. (403 aa)
	ADGRE5	Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (1130 aa)
	SRP14	Uncharacterized protein. (173 aa)
	NOS2	Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1299 aa)
	EREG	Proepiregulin. (169 aa)
	ANXA7	Annexin. (488 aa)
	ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (592 aa)
	ENSMMUP00000070228	Ribosomal_S10 domain-containing protein. (109 aa)
	RAN	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (280 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB5	ABCE1	ENSMMUP00000010273	ENSMMUP00000005913	ATP binding cassette subfamily B member 5.	ATP-binding cassette sub-family E member 1.	0.411
ABCE1	ABCB5	ENSMMUP00000005913	ENSMMUP00000010273	ATP-binding cassette sub-family E member 1.	ATP binding cassette subfamily B member 5.	0.411
ABCE1	EIF6	ENSMMUP00000005913	ENSMMUP00000056502	ATP-binding cassette sub-family E member 1.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	0.706
ABCE1	ENSMMUP00000062885	ENSMMUP00000005913	ENSMMUP00000062885	ATP-binding cassette sub-family E member 1.	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.	0.816
ABCE1	ENSMMUP00000070228	ENSMMUP00000005913	ENSMMUP00000070228	ATP-binding cassette sub-family E member 1.	Ribosomal_S10 domain-containing protein.	0.654
ABCE1	F6QKX9_MACMU	ENSMMUP00000005913	ENSMMUP00000013097	ATP-binding cassette sub-family E member 1.	Ribosomal_S10 domain-containing protein.	0.661
ABCE1	F6WSW4_MACMU	ENSMMUP00000005913	ENSMMUP00000038561	ATP-binding cassette sub-family E member 1.	Ribosomal_L6 domain-containing protein.	0.637
ABCE1	F7A4F5_MACMU	ENSMMUP00000005913	ENSMMUP00000029582	ATP-binding cassette sub-family E member 1.	Uncharacterized protein.	0.568
ABCE1	F7GUF9_MACMU	ENSMMUP00000005913	ENSMMUP00000021418	ATP-binding cassette sub-family E member 1.	Uncharacterized protein; Belongs to the universal ribosomal protein uS8 family.	0.573
ABCE1	F7HF18_MACMU	ENSMMUP00000005913	ENSMMUP00000024256	ATP-binding cassette sub-family E member 1.	Ribosomal_S10 domain-containing protein.	0.654
ABCE1	LOC693573	ENSMMUP00000005913	ENSMMUP00000066032	ATP-binding cassette sub-family E member 1.	Uncharacterized protein.	0.533
ABCE1	LOC706496	ENSMMUP00000005913	ENSMMUP00000071558	ATP-binding cassette sub-family E member 1.	Uncharacterized protein.	0.637
ABCE1	LOC709201	ENSMMUP00000005913	ENSMMUP00000038007	ATP-binding cassette sub-family E member 1.	Uncharacterized protein.	0.536
ABCE1	LOC712274	ENSMMUP00000005913	ENSMMUP00000017698	ATP-binding cassette sub-family E member 1.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.924
ABCE1	NIP7	ENSMMUP00000005913	ENSMMUP00000021874	ATP-binding cassette sub-family E member 1.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.600
ABCE1	RPL13	ENSMMUP00000005913	ENSMMUP00000023567	ATP-binding cassette sub-family E member 1.	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.	0.617
ABCE1	RPL3	ENSMMUP00000005913	ENSMMUP00000076379	ATP-binding cassette sub-family E member 1.	Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.	0.533
ABCE1	RPL9	ENSMMUP00000005913	ENSMMUP00000011218	ATP-binding cassette sub-family E member 1.	60S ribosomal protein L9.	0.644
ABCE1	RPS15A	ENSMMUP00000005913	ENSMMUP00000058879	ATP-binding cassette sub-family E member 1.	40S ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family.	0.568
ABCE1	RPS20	ENSMMUP00000005913	ENSMMUP00000065653	ATP-binding cassette sub-family E member 1.	40S ribosomal protein S20 isoform 2.	0.654