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CALB1 CALB1 CDHR1 CDHR1 CALB2 CALB2 DMD DMD APP APP GDNF GDNF GLUL GLUL VSX2 VSX2 POU4F1 POU4F1 NES NES MBP MBP GFAP GFAP OR10K2 OR10K2 DCX DCX RBFOX3 RBFOX3 BDNF BDNF SNCA SNCA OMP OMP APOD APOD AVPR2 AVPR2 RGS17 RGS17 PVALB PVALB POU4F2 POU4F2 FOS FOS S100B S100B OPN4 OPN4 CA4 CA4 TH TH UGT2A1 UGT2A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALB1Calbindin 1. (261 aa)
CDHR1Cadherin related family member 1. (859 aa)
CALB2Uncharacterized protein. (272 aa)
DMDUncharacterized protein. (3685 aa)
APPAmyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] (751 aa)
GDNFGlial cell derived neurotrophic factor. (342 aa)
GLULGlutamine synthetase. (373 aa)
VSX2Visual system homeobox 2. (361 aa)
POU4F1POU domain protein. (423 aa)
NESNestin; Belongs to the intermediate filament family. (1721 aa)
MBPMyelin basic protein. (437 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (462 aa)
OR10K2Olfactory receptor family 10 subfamily K member 2. (312 aa)
DCXDoublecortin. (387 aa)
RBFOX3RNA binding protein fox-1 homolog 3; RNA-binding protein that regulates alternative splicing events. (359 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (146 aa)
OMPOlfactory marker protein. (227 aa)
APODApolipoprotein D. (189 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (368 aa)
RGS17Regulator of G protein signaling 17. (210 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (178 aa)
POU4F2POU domain protein. (408 aa)
FOSV-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
OPN4Opsin 4. (489 aa)
CA4Carbonic anhydrase 4; Belongs to the alpha-carbonic anhydrase family. (471 aa)
THTyrosine hydroxylase. (501 aa)
UGT2A1UDP glucuronosyltransferase family 2 member A1 complex locus; Belongs to the UDP-glycosyltransferase family. (691 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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