STRINGSTRING
TIMP4 TIMP4 MMP1 MMP1 FBLN1 FBLN1 MMP7 MMP7 MMP3 MMP3 MMP12 MMP12 MMP13 MMP13 TIMP2 TIMP2 MMP11 MMP11 MMP17 MMP17 HAS3 HAS3 ACAN ACAN MMP16 MMP16 ADAMTS5 ADAMTS5 MMP14 MMP14 MMP9 MMP9 MMP10 MMP10 ADAMTS9 ADAMTS9 TIMP1 TIMP1 MMP28 MMP28 MMP2 MMP2 MMP19 MMP19 HAPLN1 HAPLN1 BCAN BCAN TIMP3 TIMP3 NCAN NCAN VCAN VCAN PCSK4 PCSK4 ADAMTS4 ADAMTS4 MMP15 MMP15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TIMP4TIMP metallopeptidase inhibitor 4. (224 aa)
MMP1Matrix metallopeptidase 1. (469 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (703 aa)
MMP7Matrix metallopeptidase 7. (270 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
MMP12Matrix metallopeptidase 12. (470 aa)
MMP13Matrix metallopeptidase 13. (471 aa)
TIMP2NTR domain-containing protein. (499 aa)
MMP11Matrix metallopeptidase 11. (488 aa)
MMP17Matrix metallopeptidase 17. (605 aa)
HAS3Uncharacterized protein. (484 aa)
ACANAggrecan. (2266 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 5. (930 aa)
MMP14Matrix metalloproteinase-14 preproprotein. (582 aa)
MMP9Uncharacterized protein. (707 aa)
MMP10Matrix metallopeptidase 10. (476 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa)
TIMP1Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity). (207 aa)
MMP28ZnMc domain-containing protein. (520 aa)
MMP272 kDa type IV collagenase isoform a preproprotein. (660 aa)
MMP19Matrix metallopeptidase 19. (508 aa)
HAPLN1Hyaluronan and proteoglycan link protein 1. (354 aa)
BCANBrevican. (945 aa)
TIMP3Metalloproteinase inhibitor 3; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15 (By similarity). (211 aa)
NCANNeurocan. (1320 aa)
VCANVersican. (3397 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (785 aa)
ADAMTS4A disintegrin and metalloproteinase with thrombospondin motifs 4 preproprotein. (837 aa)
MMP15Matrix metallopeptidase 15. (671 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.