(14 nodes) Proteasome accessory complex network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	PSMD2	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
	PSMD12	Proteasome 26S subunit, non-ATPase 12. (476 aa)
	PSMC2	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family. (433 aa)
	PSMD4	VWFA domain-containing protein. (400 aa)
	PSMD13	Proteasome 26S subunit, non-ATPase 13. (378 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
	PSMC3	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (439 aa)
	PSMC4	26S protease regulatory subunit 6B isoform 1; Belongs to the AAA ATPase family. (418 aa)
	PSMD3	26S proteasome non-ATPase regulatory subunit 3. (534 aa)
	PSMD6	Proteasome 26S subunit, non-ATPase 6. (442 aa)
	PSMD8	CSN8_PSD8_EIF3K domain-containing protein. (364 aa)
	PSMC5	26S protease regulatory subunit 8 isoform 1; Belongs to the AAA ATPase family. (406 aa)
	PSMD7	MPN domain-containing protein. (323 aa)
	PSMD11	Proteasome 26S subunit, non-ATPase 11. (454 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PSMC2	PSMC3	ENSMMUP00000004576	ENSMMUP00000020482	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.999
PSMC2	PSMC4	ENSMMUP00000004576	ENSMMUP00000022613	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	26S protease regulatory subunit 6B isoform 1; Belongs to the AAA ATPase family.	0.998
PSMC2	PSMC5	ENSMMUP00000004576	ENSMMUP00000062894	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	26S protease regulatory subunit 8 isoform 1; Belongs to the AAA ATPase family.	0.999
PSMC2	PSMD1	ENSMMUP00000004576	ENSMMUP00000015459	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.998
PSMC2	PSMD11	ENSMMUP00000004576	ENSMMUP00000073478	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 11.	0.999
PSMC2	PSMD12	ENSMMUP00000004576	ENSMMUP00000002837	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 12.	0.999
PSMC2	PSMD13	ENSMMUP00000004576	ENSMMUP00000015107	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 13.	0.999
PSMC2	PSMD2	ENSMMUP00000004576	ENSMMUP00000001091	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.998
PSMC2	PSMD3	ENSMMUP00000004576	ENSMMUP00000026819	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 3.	0.998
PSMC2	PSMD4	ENSMMUP00000004576	ENSMMUP00000010469	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	VWFA domain-containing protein.	0.999
PSMC2	PSMD6	ENSMMUP00000004576	ENSMMUP00000039564	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 6.	0.999
PSMC2	PSMD7	ENSMMUP00000004576	ENSMMUP00000065556	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	MPN domain-containing protein.	0.999
PSMC2	PSMD8	ENSMMUP00000004576	ENSMMUP00000055689	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	CSN8_PSD8_EIF3K domain-containing protein.	0.998
PSMC3	PSMC2	ENSMMUP00000020482	ENSMMUP00000004576	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	26S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family.	0.999
PSMC3	PSMC4	ENSMMUP00000020482	ENSMMUP00000022613	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	26S protease regulatory subunit 6B isoform 1; Belongs to the AAA ATPase family.	0.997
PSMC3	PSMC5	ENSMMUP00000020482	ENSMMUP00000062894	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	26S protease regulatory subunit 8 isoform 1; Belongs to the AAA ATPase family.	0.998
PSMC3	PSMD1	ENSMMUP00000020482	ENSMMUP00000015459	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.997
PSMC3	PSMD11	ENSMMUP00000020482	ENSMMUP00000073478	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 11.	0.999
PSMC3	PSMD12	ENSMMUP00000020482	ENSMMUP00000002837	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 12.	0.999
PSMC3	PSMD13	ENSMMUP00000020482	ENSMMUP00000015107	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 13.	0.999