STRINGSTRING
MNDA MNDA IRF7 IRF7 TBK1 TBK1 STING1 STING1 DDX58 DDX58 DHX58 DHX58 MAVS MAVS CGAS CGAS TLR3 TLR3 IRF3 IRF3 TICAM1 TICAM1 IKBKE IKBKE TANK TANK TRAF3 TRAF3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MNDAGamma-interferon-inducible protein 16 isoform 2. (729 aa)
IRF7Interferon regulatory factor 7. (504 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
STING1Stimulator of interferon protein. (379 aa)
DDX58Putative ATP-dependent RNA helicase DDX58. (925 aa)
DHX58DExH-box helicase 58. (678 aa)
MAVSMitochondrial antiviral-signaling protein isoform 1. (541 aa)
CGASCyclic GMP-AMP synthase. (573 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
IRF3Interferon regulatory factor 3. (450 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (711 aa)
IKBKEInhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. (716 aa)
TANKTRAF family member-associated NF-kappa-B activator isoform a. (425 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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