STRINGSTRING
ASPM ASPM KIF2A KIF2A NEFM NEFM SKA1 SKA1 CIP2A CIP2A NUF2 NUF2 CDC20B CDC20B KIFC2 KIFC2 AURKB AURKB BUB3 BUB3 NEFL NEFL DLGAP5 DLGAP5 SPC24 SPC24 WAPL WAPL KIF14 KIF14 CDCA3 CDCA3 SPAG5 SPAG5 NCAPD3 NCAPD3 PDS5B PDS5B KNTC1 KNTC1 CEP70 CEP70 SMC3 SMC3 KIF12 KIF12 DDOST DDOST MAU2 MAU2 TOP2A TOP2A KIF5C KIF5C SMC1A SMC1A KIF22 KIF22 CTBS CTBS KIF5B KIF5B KIF1C KIF1C KLC4 KLC4 H9H3J4_MACMU H9H3J4_MACMU ARHGAP11A ARHGAP11A CDKN3 CDKN3 REC8 REC8 NCAPH2 NCAPH2 NUSAP1 NUSAP1 KIF3B KIF3B ERCC6L ERCC6L ESCO1 ESCO1 KIF18B KIF18B KIF20B KIF20B KIF18A KIF18A NCAPG2 NCAPG2 RAI14 RAI14 CDCA8 CDCA8 KIF2B KIF2B TRIP13 TRIP13 CENPF CENPF KIFC3 KIFC3 CENPA CENPA ESCO2 ESCO2 PBK PBK SKA3 SKA3 KLC1 KLC1 SMC4 SMC4 PLK1 PLK1 RAD21L1 RAD21L1 STAG3 STAG3 CKAP2 CKAP2 CDCA5 CDCA5 NDC80 NDC80 KIF3C KIF3C CKAP2L CKAP2L SMC2 SMC2 KIF19 KIF19 HJURP HJURP KLC3 KLC3 ESPL1 ESPL1 KIF3A KIF3A NIPBL NIPBL ZWINT ZWINT KIF15 KIF15 KIF11 KIF11 CCNB1 CCNB1 CENPE CENPE PDS5A PDS5A ZCWPW1 ZCWPW1 CDK1 CDK1 BORA BORA KLC2 KLC2 AURKA AURKA ZCWPW2 ZCWPW2 SGO1 SGO1 ECT2 ECT2 KIF2C KIF2C CDC20 CDC20 PRC1 PRC1 KIF5A KIF5A KIF21B KIF21B KANK2 KANK2 KIF1B KIF1B KIF25 KIF25 STAG1 STAG1 MELK MELK BIRC5 BIRC5 KIFC1 KIFC1 KIF26B KIF26B BUB1B BUB1B CDCA2 CDCA2 NSL1 NSL1 BUB1 BUB1 KIF21A KIF21A NEK2 NEK2 KNL1 KNL1 KIF20A KIF20A KIF9 KIF9 PLK2 PLK2 KIF13B KIF13B ENSMMUP00000053583 ENSMMUP00000053583 ADAP1 ADAP1 SKA2 SKA2 KIF23 KIF23 NCAPD2 NCAPD2 CCNB2 CCNB2 MKI67 MKI67 KNSTRN KNSTRN KIFAP3 KIFAP3 KIF4A KIF4A NCAPG NCAPG MAD2L1BP MAD2L1BP LOC693699 LOC693699 PTTG1 PTTG1 NEFH NEFH STAG2 STAG2 MAD1L1 MAD1L1 TACC3 TACC3 MIS12 MIS12 KIF6 KIF6 TPX2 TPX2 DSN1 DSN1 CALM1 CALM1 PLK5 PLK5 MAD2L1 MAD2L1 SPC25 SPC25 CEP55 CEP55 NCAPH NCAPH INCENP INCENP KIF26A KIF26A KIF1A KIF1A RACGAP1 RACGAP1 SPDL1 SPDL1 KTN1 KTN1 RAD21 RAD21 SMC1B SMC1B TTK TTK SGO2 SGO2 KANK1 KANK1 ZWILCH ZWILCH
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ASPMAbnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3476 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
NEFMNeurofilament medium; Belongs to the intermediate filament family. (919 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
CIP2ACell proliferation regulating inhibitor of protein phosphatase 2A. (906 aa)
NUF2Kinetochore protein Nuf2. (464 aa)
CDC20BCell division cycle 20B. (518 aa)
KIFC2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (791 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
BUB3WD_REPEATS_REGION domain-containing protein. (369 aa)
NEFLNeurofilament light polypeptide; Belongs to the intermediate filament family. (543 aa)
DLGAP5DLG associated protein 5. (850 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (197 aa)
WAPLWAPL cohesin release factor. (1187 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1649 aa)
CDCA3Cell division cycle-associated protein 3. (268 aa)
SPAG5Sperm associated antigen 5. (1195 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1498 aa)
PDS5BSister chromatid cohesion protein PDS5 homolog B. (1448 aa)
KNTC1Kinetochore associated 1. (2209 aa)
CEP70Centrosomal protein of 70 kDa. (597 aa)
SMC3Structural maintenance of chromosomes protein. (1196 aa)
KIF12Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (651 aa)
DDOSTDolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1028 aa)
MAU2MAU2 sister chromatid cohesion factor. (612 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (670 aa)
CTBSChitobiase; Belongs to the glycosyl hydrolase 18 family. (382 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
KIF1CKinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1124 aa)
KLC4Kinesin light chain 4. (637 aa)
H9H3J4_MACMUUncharacterized protein. (142 aa)
ARHGAP11ARho GTPase activating protein 11A. (1023 aa)
CDKN3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (212 aa)
REC8REC8 meiotic recombination protein. (565 aa)
NCAPH2Condensin-2 complex subunit H2 isoform 2. (611 aa)
NUSAP1Nucleolar and spindle associated protein 1. (423 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1252 aa)
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (840 aa)
KIF18BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (865 aa)
KIF20BKinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1822 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (897 aa)
NCAPG2Uncharacterized protein. (1143 aa)
RAI14Retinoic acid induced 14. (986 aa)
CDCA8Cell division cycle associated 8. (280 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (670 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
CENPFCentromere protein F. (3113 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (871 aa)
CENPACentromere protein A. (138 aa)
ESCO2Establishment of sister chromatid cohesion N-acetyltransferase 2. (600 aa)
PBKPDZ binding kinase. (323 aa)
SKA3Spindle and kinetochore-associated protein 3 isoform 1. (412 aa)
KLC1Uncharacterized protein. (732 aa)
SMC4Structural maintenance of chromosomes protein. (1287 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
RAD21L1RAD21 cohesin complex component like 1. (559 aa)
STAG3SCD domain-containing protein. (1342 aa)
CKAP2Cytoskeleton associated protein 2. (682 aa)
CDCA5Cell division cycle associated 5. (252 aa)
NDC80Kinetochore protein NDC80 homolog. (642 aa)
KIF3CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (793 aa)
CKAP2LCytoskeleton associated protein 2 like. (742 aa)
SMC2Structural maintenance of chromosomes protein. (1170 aa)
KIF19Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (998 aa)
HJURPHolliday junction recognition protein. (728 aa)
KLC3Kinesin light chain 3. (504 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2120 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
NIPBLNipped-B protein. (2804 aa)
ZWINTZW10 interacting kinetochore protein. (277 aa)
KIF15Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1388 aa)
KIF11Kinesin-like protein KIF11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa)
CCNB1G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2701 aa)
PDS5ASister chromatid cohesion protein PDS5 homolog A isoform 1. (1337 aa)
ZCWPW1Zinc finger CW-type and PWWP domain containing 1. (649 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
BORABORA aurora kinase A activator. (634 aa)
KLC2Kinesin light chain 2. (635 aa)
AURKASerine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (403 aa)
ZCWPW2Zinc finger CW-type and PWWP domain containing 2. (356 aa)
SGO1Shugoshin 1. (554 aa)
ECT2Epithelial cell transforming 2. (958 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
CDC20Cell division cycle protein 20 homolog. (499 aa)
PRC1Uncharacterized protein. (624 aa)
KIF5AKinesin heavy chain isoform 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
KIF21BKinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1623 aa)
KANK2KN motif and ankyrin repeat domains 2. (851 aa)
KIF1BKinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1829 aa)
KIF25Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (891 aa)
STAG1Cohesin subunit SA-1. (1258 aa)
MELKNon-specific serine/threonine protein kinase. (651 aa)
BIRC5Baculoviral IAP repeat-containing protein 5 isoform 1. (142 aa)
KIFC1Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (849 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2107 aa)
BUB1BBUB1 mitotic checkpoint serine/threonine kinase B. (1063 aa)
CDCA2Cell division cycle associated 2. (1023 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (398 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1085 aa)
KIF21AKinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1674 aa)
NEK2Serine/threonine-protein kinase Nek2 isoform 1. (445 aa)
KNL1Kinetochore scaffold 1. (2316 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
KIF9Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (715 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
KIF13BKinesin family member 13B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1826 aa)
ENSMMUP00000053583HORMA domain-containing protein. (205 aa)
ADAP1ArfGAP with dual PH domains 1. (467 aa)
SKA2Spindle and kinetochore-associated protein 2 isoform 1. (121 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (974 aa)
NCAPD2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1440 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)
MKI67Marker of proliferation Ki-67. (3249 aa)
KNSTRNKinetochore localized astrin (SPAG5) binding protein. (316 aa)
KIFAP3Kinesin-associated protein 3 isoform 1. (792 aa)
KIF4AChromosome-associated kinesin KIF4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1234 aa)
NCAPGNon-SMC condensin I complex subunit G. (1013 aa)
MAD2L1BPMAD2L1-binding protein isoform 2. (274 aa)
LOC693699CS domain-containing protein. (157 aa)
PTTG1Securin. (202 aa)
NEFHNeurofilament heavy; Belongs to the intermediate filament family. (1017 aa)
STAG2Cohesin subunit SA-2 isoform a. (1268 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (718 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (817 aa)
MIS12Protein MIS12 homolog. (205 aa)
KIF6Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (824 aa)
TPX2TPX2 microtubule nucleation factor. (757 aa)
DSN1Kinetochore-associated protein DSN1 homolog isoform 1. (354 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (385 aa)
PLK5Serine/threonine-protein kinase PLK. (625 aa)
MAD2L1Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
SPC25Kinetochore protein Spc25. (224 aa)
CEP55Centrosomal protein 55. (464 aa)
NCAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (740 aa)
INCENPInner centromere protein. (900 aa)
KIF26AKinesin family member 26A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1920 aa)
KIF1AKinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1799 aa)
RACGAP1Rac GTPase-activating protein 1. (632 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (622 aa)
KTN1Kinectin 1. (1357 aa)
RAD21Double-strand-break repair protein rad21 homolog. (631 aa)
SMC1BStructural maintenance of chromosomes protein. (1243 aa)
TTKTTK protein kinase. (860 aa)
SGO2Shugoshin 2. (1258 aa)
KANK1ANK_REP_REGION domain-containing protein. (1364 aa)
ZWILCHZwilch kinetochore protein. (591 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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