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| | RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1297 aa) |
| | SPAG16 | Sperm associated antigen 16. (631 aa) |
| | GTF2E2 | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (320 aa) |
| | POLR2I | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa) |
| | EAF2 | EAF domain-containing protein. (261 aa) |
| | GTF2E1 | General transcription factor IIE subunit 1. (450 aa) |
| | ELL3 | Elongation factor for RNA polymerase II 3. (399 aa) |
| | MED27 | Mediator of RNA polymerase II transcription subunit 27. (311 aa) |
| | MED13L | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2210 aa) |
| | POLR2D | DNA-directed RNA polymerase II subunit RPB4. (142 aa) |
| | SIDT2 | SID1 transmembrane family member 2. (857 aa) |
| | LEO1 | RNA polymerase-associated protein LEO1. (666 aa) |
| | MED19 | Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (244 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1377 aa) |
| | MED21 | Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa) |
| | ZBTB24 | Zinc finger and BTB domain-containing protein 24 isoform 1. (697 aa) |
| | TBXAS1 | Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (580 aa) |
| | SUPT6H | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa) |
| | NELFB | Negative elongation factor complex member B. (580 aa) |
| | ELL2 | Elongation factor for RNA polymerase II 2. (641 aa) |
| | PAF1 | PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1895 aa) |
| | MLLT1 | MLLT1 super elongation complex subunit. (557 aa) |
| | LOC702124 | Uncharacterized protein. (950 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (1083 aa) |
| | CTDP1 | CTD phosphatase subunit 1. (1238 aa) |
| | MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (877 aa) |
| | MED18 | Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa) |
| | MED7 | Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (232 aa) |
| | CTR9 | CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (800 aa) |
| | POLR2J | DNA-directed RNA polymerase II subunit RPB11-a. (117 aa) |
| | TAF8 | TATA-box binding protein associated factor 8. (367 aa) |
| | GTF2F2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa) |
| | MEPCE | Methylphosphate capping enzyme. (689 aa) |
| | SIDT1 | SID1 transmembrane family member 1. (832 aa) |
| | MED10 | Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (135 aa) |
| | POLR2B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa) |
| | AFF1 | AF4/FMR2 family member 1. (1221 aa) |
| | POLR2G | S1 domain-containing protein. (209 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1251 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) |
| | RTF1 | RTF1 homolog, Paf1/RNA polymerase II complex component. (711 aa) |
| | AFF4 | AF4/FMR2 family member 4. (1162 aa) |
| | LOC106994494 | TFIIS N-terminal domain-containing protein. (529 aa) |
| | TAF4B | TATA-box binding protein associated factor 4b. (862 aa) |
| | PLPPR3 | Phospholipid phosphatase related 3. (719 aa) |
| | MED12L | Mediator complex subunit 12L. (2150 aa) |
| | HELLS | Uncharacterized protein. (883 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (2061 aa) |
| | CDK13 | Cyclin dependent kinase 13. (1511 aa) |
| | GTF2A2 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa) |
| | CDK7 | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) |
| | F6XRN0_MACMU | Ubiquitin-like domain-containing protein. (122 aa) |
| | TCEA2 | Transcription elongation factor A2. (324 aa) |
| | F6TR90_MACMU | Occludin_ELL domain-containing protein. (337 aa) |
| | CDK19 | Cyclin-dependent kinase 19. (502 aa) |
| | PLPPR4 | Phospholipid phosphatase related 4. (763 aa) |
| | ICE2 | Interactor of little elongation complex ELL subunit 2. (982 aa) |
| | C14H11orf88 | Chromosome 14 C11orf88 homolog. (197 aa) |
| | TAF7L | TATA-box binding protein associated factor 7 like. (505 aa) |
| | ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (375 aa) |
| | GTF2A1 | Transcription initiation factor IIA subunit 1 isoform 1. (376 aa) |
| | PLPPR2 | Lipid phosphate phosphatase-related protein type 2 isoform 2. (452 aa) |
| | CYP3A43 | Uncharacterized protein. (504 aa) |
| | MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2174 aa) |
| | SUPT5H | Transcription elongation factor SPT5. (1087 aa) |
| | NELFE | Negative elongation factor complex member E. (338 aa) |
| | MED24 | Mediator of RNA polymerase II transcription subunit 24 isoform 1. (989 aa) |
| | F7HPQ9_MACMU | TAFII28 domain-containing protein. (199 aa) |
| | F7HPQ7_MACMU | TAFII28 domain-containing protein. (196 aa) |
| | ICE1 | Interactor of little elongation complex ELL subunit 1. (2266 aa) |
| | CCNT2 | Cyclin T2; Belongs to the cyclin family. (709 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (1008 aa) |
| | DRAP1 | Dr1-associated corepressor. (205 aa) |
| | MED15 | Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (788 aa) |
| | F7GDN6_MACMU | Protein kinase domain-containing protein. (165 aa) |
| | TCEANC2 | Transcription elongation factor A N-terminal and central domain-containing protein 2. (208 aa) |
| | DDX11 | DEAD/H-box helicase 11. (970 aa) |
| | ZC3H8 | Zinc finger CCCH-type containing 8. (295 aa) |
| | CCNC | Cyclin C; Belongs to the cyclin family. (282 aa) |
| | TAF1L | TATA-box binding protein associated factor 1 like. (1776 aa) |
| | MED14 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa) |
| | POLR2H | RNA polymerase II subunit H. (175 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | BTAF1 | B-TFIID TATA-box binding protein associated factor 1. (1858 aa) |
| | ENSMMUP00000044764 | TFIIA_gamma_C domain-containing protein. (74 aa) |
| | TAF11 | Transcription initiation factor TFIID subunit 11. (211 aa) |
| | CDCA7 | Cell division cycle-associated protein 7 isoform 1. (450 aa) |
| | MED8 | Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (378 aa) |
| | POLR2E | RNA polymerase II subunit E. (160 aa) |
| | TCEA3 | Transcription elongation factor A3. (348 aa) |
| | ERCC2 | TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa) |
| | CDK20 | Cyclin-dependent kinase 20; Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling. Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. (346 aa) |
| | SUPT4H1 | Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa) |
| | TBP | TATA-box binding protein. (326 aa) |
| | EAF1 | ELL-associated factor 1. (268 aa) |
| | MED12 | Mediator complex subunit 12. (2178 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (331 aa) |
| | CDK8 | Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (461 aa) |
| | MED23 | Mediator complex subunit 23. (1374 aa) |
| | TCEA1 | Transcription elongation factor A protein 1 isoform 1. (301 aa) |
| | MED6 | Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (257 aa) |
| | MED25 | Mediator complex subunit 25. (796 aa) |
| | MMS22L | MMS22 like, DNA repair protein. (1243 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (678 aa) |
| | ELL | Elongation factor for RNA polymerase II. (621 aa) |
| | GTF2H2 | General transcription factor IIH subunit. (399 aa) |
| | NELFA | Negative elongation factor complex member A. (539 aa) |
| | MED30 | Mediator of RNA polymerase II transcription subunit 30. (178 aa) |
| | STON1 | Stonin-1; May be involved in the endocytic machinery. (1182 aa) |
| | POLR2F | Uncharacterized protein. (179 aa) |
| | NELFCD | Negative elongation factor complex member C/D. (599 aa) |
| | MED11 | Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (206 aa) |
| | ENSMMUP00000058345 | TAFII28 domain-containing protein. (199 aa) |
| | GTF2H3 | General transcription factor IIH subunit 3. (308 aa) |
| | RPAP2 | Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2. (612 aa) |
| | CCNK | Cyclin K; Belongs to the cyclin family. (580 aa) |
| | POLR2A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa) |
| | MED29 | Mediator complex subunit 29. (200 aa) |
| | MED9 | Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (156 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) |
| | PLPPR5 | Phospholipid phosphatase related 5. (340 aa) |
| | MED26 | TFIIS N-terminal domain-containing protein. (615 aa) |
| | GTF2H1 | General transcription factor IIH subunit 1. (548 aa) |
| | EEPD1 | Endonuclease/exonuclease/phosphatase family domain containing 1. (569 aa) |
| | GTF2H5 | General transcription factor IIH subunit 5. (71 aa) |
| | ERCC3 | TFIIH basal transcription factor complex helicase XPB subunit. (782 aa) |
| | CDK12 | Cyclin-dependent kinase 12 isoform 2. (1481 aa) |
| | MED17 | DUF1907 domain-containing protein. (838 aa) |
| | HROB | Chromosome 16 C17orf53 homolog. (664 aa) |
| | TBPL1 | TATA box-binding protein-like protein 1. (186 aa) |
| | TCEANC | Transcription elongation factor A N-terminal and central domain containing. (350 aa) |
| | TAF9B | TATA-box binding protein associated factor 9b. (290 aa) |
| | HEXIM1 | Protein HEXIM1. (359 aa) |
| | LARP7 | La ribonucleoprotein domain family member 7. (581 aa) |
| | UVSSA | UV stimulated scaffold protein A. (769 aa) |
| | TAF13 | Transcription initiation factor TFIID subunit 13. (124 aa) |
| | CCNT1 | Cyclin T1; Belongs to the cyclin family. (728 aa) |
| | TAF12 | TFIID_20kDa domain-containing protein. (214 aa) |
| | CDC73 | Parafibromin. (531 aa) |
| | BCLAF1 | Bcl-2-associated transcription factor 1 isoform 1. (921 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (721 aa) |
| | CDK9 | Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa) |
| | ELOA | Elongin A. (846 aa) |
| | POLR2C | RNA polymerase II subunit C. (306 aa) |
| | TAF7 | Transcription initiation factor TFIID subunit 7. (349 aa) |
| | HEXIM2 | HEXIM P-TEFb complex subunit 2. (339 aa) |
| | GTF2B | General transcription factor IIB. (312 aa) |
| | MLLT3 | MLLT3 super elongation complex subunit. (600 aa) |
| | C6orf15 | Uncharacterized protein C6orf15 homolog. (314 aa) |
| | THRAP3 | Thyroid hormone receptor-associated protein 3. (955 aa) |
| | MED31 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa) |
| | BCLAF3 | BCLAF1 and THRAP3 family member 3. (691 aa) |
| | LOC100426235 | Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (252 aa) |
| | EZHIP | EZH inhibitory protein. (487 aa) |
| | UPK3BL2 | Uncharacterized protein. (266 aa) |
| | IWS1 | Interacts with SUPT6H, CTD assembly factor 1. (818 aa) |
| | MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (362 aa) |
| | GTF2H4 | General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa) |
