STRINGSTRING
GTF2E2 GTF2E2 GTF2E1 GTF2E1 GTF2F2 GTF2F2 GTF2A2 GTF2A2 CDK7 CDK7 GTF2A1 GTF2A1 MNAT1 MNAT1 ERCC2 ERCC2 TBP TBP CCNH CCNH GTF2H2 GTF2H2 GTF2H3 GTF2H3 GTF2H1 GTF2H1 GTF2H5 GTF2H5 ERCC3 ERCC3 GTF2B GTF2B GTF2H4 GTF2H4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (320 aa)
GTF2E1General transcription factor IIE subunit 1. (450 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
GTF2A1Transcription initiation factor IIA subunit 1 isoform 1. (376 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
TBPTATA-box binding protein. (326 aa)
CCNHCyclin H; Belongs to the cyclin family. (331 aa)
GTF2H2General transcription factor IIH subunit. (399 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (782 aa)
GTF2BGeneral transcription factor IIB. (312 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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