STRINGSTRING
SNRPD3 SNRPD3 TXNL4A TXNL4A RBM25 RBM25 CWC25 CWC25 SYF2 SYF2 PQBP1 PQBP1 SF3A1 SF3A1 PRPF4 PRPF4 HTATSF1 HTATSF1 PPIL3 PPIL3 SNRPD2 SNRPD2 SF3B4 SF3B4 CRNKL1 CRNKL1 UBL5 UBL5 RBMX2 RBMX2 SNRNP35 SNRNP35 IK IK SNRPB SNRPB SNRNP27 SNRNP27 ISY1 ISY1 SF3B2 SF3B2 EFTUD2 EFTUD2 PRPF38A PRPF38A CDC5L CDC5L BCAS2 BCAS2 PRPF19 PRPF19 SNRNP48 SNRNP48 ZC2HC1C ZC2HC1C PRPF6 PRPF6 PRPF3 PRPF3 PPWD1 PPWD1 ZCRB1 ZCRB1 LSM10 LSM10 SF3B3 SF3B3 USP39 USP39 RNPC3 RNPC3 PPIE PPIE RBM42 RBM42 WBP11 WBP11 SNRNP40 SNRNP40 DHX16 DHX16 RNF113A RNF113A RBM22 RBM22 F7HQG4_MACMU F7HQG4_MACMU SF3B1 SF3B1 MFAP1 MFAP1 PPIL4 PPIL4 SLU7 SLU7 SNRNP200 SNRNP200 LRMDA LRMDA SNRNP70 SNRNP70 WDR25 WDR25 SNRPC SNRPC DDX46 DDX46 LUC7L3 LUC7L3 PRPF18 PRPF18 CWF19L2 CWF19L2 SF1 SF1 CTNNBL1 CTNNBL1 DHX35 DHX35 ZCCHC17 ZCCHC17 SRRM1 SRRM1 SNRPD2-2 SNRPD2-2 CWC27 CWC27 LSM2 LSM2 SNRPA SNRPA TCERG1 TCERG1 LOC711104 LOC711104 PRPF39 PRPF39 WBP4 WBP4 LSM7 LSM7 BUD13 BUD13 SNRPC-2 SNRPC-2 SNW1 SNW1 PDCD7 PDCD7 SRRM3 SRRM3 DDX42 DDX42 DDX23 DDX23 TMIGD2 TMIGD2 PLRG1 PLRG1 ENSMMUP00000056838 ENSMMUP00000056838 PRPF40B PRPF40B CDC40 CDC40 SF3B6 SF3B6 CWC22 CWC22 CWC15 CWC15 PPIL2 PPIL2 SRRM2 SRRM2 GPKOW GPKOW SNRPA1 SNRPA1 ZRSR2 ZRSR2 NAA38-2 NAA38-2 PRPF31 PRPF31 LSM6 LSM6 SART1 SART1 ENSMMUP00000067050 ENSMMUP00000067050 SNRPE SNRPE ZMAT5 ZMAT5 RBM41 RBM41 SNRPD1 SNRPD1 TXNL4B TXNL4B YJU2 YJU2 ENSMMUP00000068859 ENSMMUP00000068859 LSM5 LSM5 XAB2 XAB2 ENSMMUP00000069555 ENSMMUP00000069555 PRPF8 PRPF8 PRPF40A PRPF40A ENSMMUP00000070804 ENSMMUP00000070804 SNRPG SNRPG PHF5A PHF5A SF3A3 SF3A3 BUD31 BUD31 CD2BP2 CD2BP2 CCDC12 CCDC12 AQR AQR PPIL1 PPIL1 SNRPB2 SNRPB2 ZMAT2 ZMAT2 LSM3 LSM3 SF3A2 SF3A2 DHX38 DHX38 LUC7L LUC7L LSM4 LSM4 PRR3 PRR3 SMU1 SMU1 SNIP1 SNIP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNRPD3Small nuclear ribonucleoprotein D3 polypeptide. (259 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
RBM25RNA binding motif protein 25. (843 aa)
CWC25CWC25 spliceosome associated protein homolog. (427 aa)
SYF2SYF2 pre-mRNA splicing factor. (243 aa)
PQBP1Polyglutamine binding protein 1. (286 aa)
SF3A1Splicing factor 3A subunit 1 isoform 1. (793 aa)
PRPF4U4/U6 small nuclear ribonucleoprotein Prp4. (521 aa)
HTATSF1HIV-1 Tat specific factor 1. (754 aa)
PPIL3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
SF3B4Splicing factor 3B subunit 4. (424 aa)
CRNKL1Crooked neck pre-mRNA splicing factor 1. (813 aa)
UBL5Ubiquitin-like protein 5. (73 aa)
RBMX2RNA-binding motif protein, X-linked 2. (322 aa)
SNRNP35Small nuclear ribonucleoprotein U11/U12 subunit 35. (270 aa)
IKIK cytokine. (557 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
SNRNP27U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein. (155 aa)
ISY1Uncharacterized protein. (408 aa)
SF3B2Splicing factor 3B subunit 2. (895 aa)
EFTUD2116 kDa U5 small nuclear ribonucleoprotein component isoform a. (972 aa)
PRPF38APre-mRNA-splicing factor 38A. (312 aa)
CDC5LCell division cycle 5-like protein. (802 aa)
BCAS2Pre-mRNA-splicing factor SPF27. (225 aa)
PRPF19Pre-mRNA processing factor 19. (512 aa)
SNRNP48Uncharacterized protein. (339 aa)
ZC2HC1CZinc finger C2HC-type containing 1C. (531 aa)
PRPF6Pre-mRNA processing factor 6. (920 aa)
PRPF3Pre-mRNA processing factor 3. (670 aa)
PPWD1Peptidylprolyl isomerase domain and WD repeat containing 1. (747 aa)
ZCRB1Zinc finger CCHC-type and RNA-binding motif-containing protein 1. (217 aa)
LSM10U7 snRNA-associated Sm-like protein LSm10. (123 aa)
SF3B3Spliceosome-associated protein 130. (1217 aa)
USP39Ubiquitin specific peptidase 39. (732 aa)
RNPC3RNA binding region (RNP1, RRM) containing 3. (518 aa)
PPIEPeptidylprolyl isomerase E. (369 aa)
RBM42RNA-binding motif protein 42. (480 aa)
WBP11WW domain-binding protein 11. (641 aa)
SNRNP40WD_REPEATS_REGION domain-containing protein. (358 aa)
DHX16Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 isoform 1. (1044 aa)
RNF113ARING finger protein 113A. (344 aa)
RBM22Pre-mRNA-splicing factor RBM22. (420 aa)
F7HQG4_MACMURRM domain-containing protein. (281 aa)
SF3B1SF3b1 domain-containing protein. (1310 aa)
MFAP1Microfibrillar-associated protein 1. (439 aa)
PPIL4Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (492 aa)
SLU7Pre-mRNA-splicing factor SLU7. (586 aa)
SNRNP200U5 small nuclear ribonucleoprotein 200 kDa helicase. (2136 aa)
LRMDALeucine rich melanocyte differentiation associated. (226 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (428 aa)
WDR25WD repeat domain 25. (536 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (159 aa)
DDX46Putative ATP-dependent RNA helicase DDX46. (1032 aa)
LUC7L3LUC7 like 3 pre-mRNA splicing factor. (489 aa)
PRPF18SFM domain-containing protein. (352 aa)
CWF19L2CWF19 like cell cycle control factor 2. (893 aa)
SF1Splicing factor 1 isoform 1. (639 aa)
CTNNBL1DUF1716 domain-containing protein. (579 aa)
DHX35DEAH-box helicase 35. (777 aa)
ZCCHC17Uncharacterized protein. (252 aa)
SRRM1Serine and arginine repetitive matrix 1. (906 aa)
SNRPD2-2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
CWC27Peptidyl-prolyl cis-trans isomerase CWC27 homolog. (473 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (282 aa)
TCERG1Transcription elongation regulator 1. (1115 aa)
LOC711104Uncharacterized protein. (458 aa)
PRPF39Pre-mRNA processing factor 39. (671 aa)
WBP4WW domain binding protein 4. (375 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (107 aa)
BUD13BUD13 homolog. (619 aa)
SNRPC-2U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
SNW1SNW domain-containing protein 1. (536 aa)
PDCD7Programmed cell death 7. (743 aa)
SRRM3Serine/arginine repetitive matrix 3. (654 aa)
DDX42ATP-dependent RNA helicase DDX42. (937 aa)
DDX23Probable ATP-dependent RNA helicase DDX23. (820 aa)
TMIGD2Transmembrane and immunoglobulin domain containing 2. (302 aa)
PLRG1Pleiotropic regulator 1 isoform 1. (514 aa)
ENSMMUP00000056838Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (53 aa)
PRPF40BPre-mRNA processing factor 40 homolog B. (892 aa)
CDC40Pre-mRNA-processing factor 17. (579 aa)
SF3B6Pre-mRNA branch site protein p14. (125 aa)
CWC22CWC22 spliceosome associated protein homolog. (907 aa)
CWC15Protein CWC15 homolog. (229 aa)
PPIL2Peptidylprolyl isomerase like 2. (519 aa)
SRRM2Serine/arginine repetitive matrix 2. (2752 aa)
GPKOWG-patch domain and KOW motifs. (508 aa)
SNRPA1LRRcap domain-containing protein. (277 aa)
ZRSR2Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2. (479 aa)
NAA38-2U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
PRPF31Pre-mRNA processing factor 31. (525 aa)
LSM6U6 snRNA-associated Sm-like protein LSm6. (80 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
ENSMMUP00000067050Uncharacterized protein; Belongs to the DEAD box helicase family. (588 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (145 aa)
ZMAT5C3H1-type domain-containing protein. (256 aa)
RBM41RNA binding motif protein 41. (556 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (152 aa)
TXNL4BUncharacterized protein. (163 aa)
YJU2YJU2 splicing factor homolog. (369 aa)
ENSMMUP00000068859Uncharacterized protein. (577 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (102 aa)
XAB2Pre-mRNA-splicing factor SYF1. (855 aa)
ENSMMUP00000069555Uncharacterized protein. (71 aa)
PRPF8Pre-mRNA processing factor 8. (2339 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (957 aa)
ENSMMUP00000070804Sm domain-containing protein. (166 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (79 aa)
PHF5APHD finger-like domain-containing protein 5A. (110 aa)
SF3A3Splicing factor 3a subunit 3. (504 aa)
BUD31Protein BUD31 homolog. (144 aa)
CD2BP2CD2 antigen cytoplasmic tail-binding protein 2. (341 aa)
CCDC12Coiled-coil domain containing 12. (323 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
SNRPB2U2 small nuclear ribonucleoprotein B'. (225 aa)
ZMAT2Zinc finger matrin-type 2. (305 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
SF3A2Splicing factor 3a subunit 2. (482 aa)
DHX38Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16. (1227 aa)
LUC7LPutative RNA-binding protein Luc7-like 1 isoform b. (371 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (146 aa)
PRR3C3H1-type domain-containing protein. (188 aa)
SMU1Smu-1 suppressor of mec-8 and unc-52 protein-like protein. (513 aa)
SNIP1Smad nuclear-interacting protein 1. (396 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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