STRINGSTRING
SNRPD3 SNRPD3 TXNL4A TXNL4A SF3A1 SF3A1 PRPF4 PRPF4 SNRPD2 SNRPD2 SNRPB SNRPB EFTUD2 EFTUD2 PRPF6 PRPF6 PRPF3 PRPF3 LSM10 LSM10 SNRNP40 SNRNP40 SNRNP200 SNRNP200 SNRNP70 SNRNP70 SNRPC SNRPC SNRPD2-2 SNRPD2-2 LSM2 LSM2 SNRPA SNRPA LSM7 LSM7 SNRPC-2 SNRPC-2 DDX23 DDX23 ENSMMUP00000056838 ENSMMUP00000056838 SNRPA1 SNRPA1 NAA38-2 NAA38-2 PRPF31 PRPF31 LSM6 LSM6 SART1 SART1 SNRPE SNRPE SNRPD1 SNRPD1 LSM5 LSM5 ENSMMUP00000069555 ENSMMUP00000069555 PRPF8 PRPF8 ENSMMUP00000070804 ENSMMUP00000070804 SNRPG SNRPG SF3A3 SF3A3 SNRPB2 SNRPB2 LSM3 LSM3 SF3A2 SF3A2 LSM4 LSM4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNRPD3Small nuclear ribonucleoprotein D3 polypeptide. (259 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
SF3A1Splicing factor 3A subunit 1 isoform 1. (793 aa)
PRPF4U4/U6 small nuclear ribonucleoprotein Prp4. (521 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
EFTUD2116 kDa U5 small nuclear ribonucleoprotein component isoform a. (972 aa)
PRPF6Pre-mRNA processing factor 6. (920 aa)
PRPF3Pre-mRNA processing factor 3. (670 aa)
LSM10U7 snRNA-associated Sm-like protein LSm10. (123 aa)
SNRNP40WD_REPEATS_REGION domain-containing protein. (358 aa)
SNRNP200U5 small nuclear ribonucleoprotein 200 kDa helicase. (2136 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (428 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (159 aa)
SNRPD2-2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (282 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (107 aa)
SNRPC-2U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
DDX23Probable ATP-dependent RNA helicase DDX23. (820 aa)
ENSMMUP00000056838Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (53 aa)
SNRPA1LRRcap domain-containing protein. (277 aa)
NAA38-2U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
PRPF31Pre-mRNA processing factor 31. (525 aa)
LSM6U6 snRNA-associated Sm-like protein LSm6. (80 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (145 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (152 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (102 aa)
ENSMMUP00000069555Uncharacterized protein. (71 aa)
PRPF8Pre-mRNA processing factor 8. (2339 aa)
ENSMMUP00000070804Sm domain-containing protein. (166 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (79 aa)
SF3A3Splicing factor 3a subunit 3. (504 aa)
SNRPB2U2 small nuclear ribonucleoprotein B'. (225 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
SF3A2Splicing factor 3a subunit 2. (482 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (146 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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