(13 nodes) mRNA decay by 5 to 3 exoribonuclease network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	YJEFN3	YjeF N-terminal domain containing 3. (299 aa)
	EDC4	Enhancer of mRNA-decapping protein 4. (1401 aa)
	DCP2	mRNA-decapping enzyme 2 isoform 1. (420 aa)
	PATL2	PAT1 homolog 2. (542 aa)
	PATL1	PAT1 homolog 1, processing body mRNA decay factor. (804 aa)
	XRN1	5'-3' exoribonuclease 1. (1707 aa)
	DCP1A	mRNA-decapping enzyme 1A. (582 aa)
	ENSMMUP00000054359	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (91 aa)
	DDX6	Putative ATP-dependent RNA helicase DDX6; Belongs to the DEAD box helicase family. (483 aa)
	C19H19orf54	Chromosome 19 open reading frame 54. (351 aa)
	DCP1B	Decapping mRNA 1B. (617 aa)
	EDC3	Enhancer of mRNA-decapping protein 3. (508 aa)
	LSM14B	Uncharacterized protein. (424 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C19H19orf54	DCP1A	ENSMMUP00000070437	ENSMMUP00000044115	Chromosome 19 open reading frame 54.	mRNA-decapping enzyme 1A.	0.611
C19H19orf54	DCP1B	ENSMMUP00000070437	ENSMMUP00000072396	Chromosome 19 open reading frame 54.	Decapping mRNA 1B.	0.611
C19H19orf54	DCP2	ENSMMUP00000070437	ENSMMUP00000017826	Chromosome 19 open reading frame 54.	mRNA-decapping enzyme 2 isoform 1.	0.800
C19H19orf54	DDX6	ENSMMUP00000070437	ENSMMUP00000068224	Chromosome 19 open reading frame 54.	Putative ATP-dependent RNA helicase DDX6; Belongs to the DEAD box helicase family.	0.778
C19H19orf54	EDC3	ENSMMUP00000070437	ENSMMUP00000072782	Chromosome 19 open reading frame 54.	Enhancer of mRNA-decapping protein 3.	0.739
C19H19orf54	EDC4	ENSMMUP00000070437	ENSMMUP00000015608	Chromosome 19 open reading frame 54.	Enhancer of mRNA-decapping protein 4.	0.612
C19H19orf54	ENSMMUP00000054359	ENSMMUP00000070437	ENSMMUP00000054359	Chromosome 19 open reading frame 54.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.923
C19H19orf54	PATL1	ENSMMUP00000070437	ENSMMUP00000022745	Chromosome 19 open reading frame 54.	PAT1 homolog 1, processing body mRNA decay factor.	0.836
C19H19orf54	PATL2	ENSMMUP00000070437	ENSMMUP00000018774	Chromosome 19 open reading frame 54.	PAT1 homolog 2.	0.836
C19H19orf54	XRN1	ENSMMUP00000070437	ENSMMUP00000038546	Chromosome 19 open reading frame 54.	5'-3' exoribonuclease 1.	0.896
C19H19orf54	YJEFN3	ENSMMUP00000070437	ENSMMUP00000014899	Chromosome 19 open reading frame 54.	YjeF N-terminal domain containing 3.	0.556
DCP1A	C19H19orf54	ENSMMUP00000044115	ENSMMUP00000070437	mRNA-decapping enzyme 1A.	Chromosome 19 open reading frame 54.	0.611
DCP1A	DCP1B	ENSMMUP00000044115	ENSMMUP00000072396	mRNA-decapping enzyme 1A.	Decapping mRNA 1B.	0.986
DCP1A	DCP2	ENSMMUP00000044115	ENSMMUP00000017826	mRNA-decapping enzyme 1A.	mRNA-decapping enzyme 2 isoform 1.	0.992
DCP1A	DDX6	ENSMMUP00000044115	ENSMMUP00000068224	mRNA-decapping enzyme 1A.	Putative ATP-dependent RNA helicase DDX6; Belongs to the DEAD box helicase family.	0.991
DCP1A	EDC3	ENSMMUP00000044115	ENSMMUP00000072782	mRNA-decapping enzyme 1A.	Enhancer of mRNA-decapping protein 3.	0.982
DCP1A	EDC4	ENSMMUP00000044115	ENSMMUP00000015608	mRNA-decapping enzyme 1A.	Enhancer of mRNA-decapping protein 4.	0.969
DCP1A	ENSMMUP00000054359	ENSMMUP00000044115	ENSMMUP00000054359	mRNA-decapping enzyme 1A.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.654
DCP1A	LSM14B	ENSMMUP00000044115	ENSMMUP00000077330	mRNA-decapping enzyme 1A.	Uncharacterized protein.	0.694
DCP1A	PATL1	ENSMMUP00000044115	ENSMMUP00000022745	mRNA-decapping enzyme 1A.	PAT1 homolog 1, processing body mRNA decay factor.	0.968