17 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SETMAR	SET domain and mariner transposase fusion gene. (684 aa)
	SLX1A	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (437 aa)
	SLX4	SLX4 structure-specific endonuclease subunit. (1668 aa)
	BRIP1	BRCA1 interacting protein C-terminal helicase 1. (1189 aa)
	UBE2V2	Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
	RNF138	Ring finger protein 138. (245 aa)
	HELQ	Helicase, POLQ like. (1101 aa)
	C7H14orf39	Chromosome 7 C14orf39 homolog. (587 aa)
	RAD52	RAD52 homolog, DNA repair protein. (442 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (396 aa)
	BLM	BLM RecQ like helicase. (1416 aa)
	EXD2	Exonuclease 3'-5' domain containing 2. (620 aa)
	RBBP8	Uncharacterized protein. (898 aa)
	UBE2N	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
	SMARCAD1	annotation not available (1026 aa)
	ENSMMUP00000058534	UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
	DNA2	DNA replication helicase/nuclease 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (1316 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLM	BRIP1	ENSMMUP00000025651	ENSMMUP00000011828	BLM RecQ like helicase.	BRCA1 interacting protein C-terminal helicase 1.	0.741
BLM	DNA2	ENSMMUP00000025651	ENSMMUP00000062574	BLM RecQ like helicase.	DNA replication helicase/nuclease 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.949
BLM	ENSMMUP00000058534	ENSMMUP00000025651	ENSMMUP00000058534	BLM RecQ like helicase.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.427
BLM	EXD2	ENSMMUP00000025651	ENSMMUP00000027016	BLM RecQ like helicase.	Exonuclease 3'-5' domain containing 2.	0.494
BLM	HELQ	ENSMMUP00000025651	ENSMMUP00000020129	BLM RecQ like helicase.	Helicase, POLQ like.	0.420
BLM	RAD52	ENSMMUP00000025651	ENSMMUP00000024536	BLM RecQ like helicase.	RAD52 homolog, DNA repair protein.	0.964
BLM	RBBP8	ENSMMUP00000025651	ENSMMUP00000048570	BLM RecQ like helicase.	Uncharacterized protein.	0.805
BLM	SLX1A	ENSMMUP00000025651	ENSMMUP00000009615	BLM RecQ like helicase.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	0.938
BLM	SLX4	ENSMMUP00000025651	ENSMMUP00000009940	BLM RecQ like helicase.	SLX4 structure-specific endonuclease subunit.	0.695
BLM	SMARCAD1	ENSMMUP00000025651	ENSMMUP00000054311	BLM RecQ like helicase.	annotation not available	0.640
BLM	SPO11	ENSMMUP00000025651	ENSMMUP00000000347	BLM RecQ like helicase.	SPO11 initiator of meiotic double stranded breaks.	0.659
BLM	UBE2N	ENSMMUP00000025651	ENSMMUP00000051689	BLM RecQ like helicase.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.420
BLM	UBE2V2	ENSMMUP00000025651	ENSMMUP00000016046	BLM RecQ like helicase.	Ubiquitin-conjugating enzyme E2 variant 2.	0.427
BRIP1	BLM	ENSMMUP00000011828	ENSMMUP00000025651	BRCA1 interacting protein C-terminal helicase 1.	BLM RecQ like helicase.	0.741
BRIP1	DNA2	ENSMMUP00000011828	ENSMMUP00000062574	BRCA1 interacting protein C-terminal helicase 1.	DNA replication helicase/nuclease 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.663
BRIP1	EXD2	ENSMMUP00000011828	ENSMMUP00000027016	BRCA1 interacting protein C-terminal helicase 1.	Exonuclease 3'-5' domain containing 2.	0.430
BRIP1	RAD52	ENSMMUP00000011828	ENSMMUP00000024536	BRCA1 interacting protein C-terminal helicase 1.	RAD52 homolog, DNA repair protein.	0.664
BRIP1	RBBP8	ENSMMUP00000011828	ENSMMUP00000048570	BRCA1 interacting protein C-terminal helicase 1.	Uncharacterized protein.	0.705
BRIP1	SLX1A	ENSMMUP00000011828	ENSMMUP00000009615	BRCA1 interacting protein C-terminal helicase 1.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	0.597
BRIP1	SLX4	ENSMMUP00000011828	ENSMMUP00000009940	BRCA1 interacting protein C-terminal helicase 1.	SLX4 structure-specific endonuclease subunit.	0.671