STRINGSTRING
MAD2L1 MAD2L1 PLK5 PLK5 SMC6 SMC6 MAD1L1 MAD1L1 STAG2 STAG2 CDC6 CDC6 CDC14A CDC14A CEP63 CEP63 RMDN1 RMDN1 MISP MISP LOC693699 LOC693699 CTNNB1 CTNNB1 FAM110C FAM110C RASSF1 RASSF1 NUDCD2 NUDCD2 NUBP2 NUBP2 KNSTRN KNSTRN FAM193A FAM193A ALMS1 ALMS1 PLK3 PLK3 YPEL5 YPEL5 EFCAB3 EFCAB3 UMOD UMOD NEK6 NEK6 KNTC1 KNTC1 AUNIP AUNIP SMC3 SMC3 MAPK14 MAPK14 BCCIP BCCIP CTDP1 CTDP1 SMC1A SMC1A IK IK GPSM2 GPSM2 EFCAB13 EFCAB13 PKP4 PKP4 EML1 EML1 CETN1 CETN1 UNC119 UNC119 ABRAXAS2 ABRAXAS2 CNTRL CNTRL KIF20B KIF20B EFHC1 EFHC1 ARHGEF7 ARHGEF7 BOD1 BOD1 FAM161A FAM161A ALPK1 ALPK1 CSPP1 CSPP1 HSF1 HSF1 CCDC155 CCDC155 F6VV14_MACMU F6VV14_MACMU PSRC1 PSRC1 DCTN1 DCTN1 CENPF CENPF NPM1 NPM1 KATNAL2 KATNAL2 FBF1 FBF1 TUBGCP4 TUBGCP4 PLK1 PLK1 CALML5 CALML5 FAM110A FAM110A GIT1 GIT1 DYNC1LI1 DYNC1LI1 ENSMMUP00000055202 ENSMMUP00000055202 FRY FRY TUBGCP3 TUBGCP3 ENSMMUP00000053583 ENSMMUP00000053583 BOD1L1 BOD1L1 HAUS1 HAUS1 CDC14C CDC14C CEP95 CEP95 POC1A POC1A STAG1 STAG1 BRCC3 BRCC3 LOC717686 LOC717686 KATNA1 KATNA1 DNAAF1 DNAAF1 CDC25B CDC25B NEDD9 NEDD9 SBDS SBDS PRC1 PRC1 IKBKG IKBKG KLHL21 KLHL21 CDC20 CDC20 DDX11 DDX11 SPOUT1 SPOUT1 ODF2 ODF2 GOLGA2 GOLGA2 LOC713290 LOC713290 NDUFB6 NDUFB6 POC1B POC1B SGO1 SGO1 AURKA AURKA HNRNPU HNRNPU CUL3 CUL3 RASSF10 RASSF10 KATNAL1 KATNAL1 CCNB1 CCNB1 RGS14 RGS14 NUP62 NUP62 ZW10 ZW10 KIF11 KIF11 CDK5RAP2 CDK5RAP2 TUBGCP2 TUBGCP2 NEK7 NEK7 PPP2CB PPP2CB KAT5 KAT5 WDR62 WDR62 LATS2 LATS2 UXT UXT CEP89 CEP89 AAAS AAAS ENSMMUP00000067677 ENSMMUP00000067677 ANKRD53 ANKRD53 CKAP5 CKAP5 NEK2 NEK2 TUBGCP6 TUBGCP6 ENSMMUP00000048641 ENSMMUP00000048641 CEP44 CEP44 MAPRE1 MAPRE1 RMDN2 RMDN2 ENSMMUP00000072883 ENSMMUP00000072883 RMDN3 RMDN3 TOPBP1 TOPBP1 ASPM ASPM RAE1 RAE1 PLEKHG6 PLEKHG6 HAUS8 HAUS8 CEP85 CEP85 TNKS TNKS UBXN2B UBXN2B WDR73 WDR73 AURKB AURKB DLGAP5 DLGAP5 MAPKBP1 MAPKBP1 NEDD1 NEDD1 F7DC82_MACMU F7DC82_MACMU LOC114675405 LOC114675405 DYNC1I1 DYNC1I1 CDC14B CDC14B SPAG5 SPAG5 ENSMMUP00000073741 ENSMMUP00000073741 RALBP1 RALBP1 BEX4 BEX4 BIRC6 BIRC6 MTCL1 MTCL1 ENSMMUP00000074770 ENSMMUP00000074770 SPDL1 SPDL1 RAD21 RAD21 CEP19 CEP19 TBCCD1 TBCCD1 LOC114675592 LOC114675592 CALM3 CALM3 MISP3 MISP3 SBDS-2 SBDS-2 TMEM201 TMEM201 LOC114669849 LOC114669849 CALM1 CALM1 NDE1 NDE1 TPX2 TPX2 CEP104 CEP104 TACC3 TACC3 KATNBL1 KATNBL1 LATS1 LATS1 CEP128 CEP128 NIN NIN KATNB1 KATNB1 NUMA1 NUMA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAD2L1Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
PLK5Serine/threonine-protein kinase PLK. (625 aa)
SMC6Structural maintenance of chromosomes 6. (1092 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (718 aa)
STAG2Cohesin subunit SA-2 isoform a. (1268 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (632 aa)
CDC14ACell division cycle 14A. (636 aa)
CEP63Centrosomal protein 63. (703 aa)
RMDN1Regulator of microtubule dynamics 1. (314 aa)
MISPMitotic spindle positioning. (679 aa)
LOC693699CS domain-containing protein. (157 aa)
CTNNB1Catenin beta-1. (781 aa)
FAM110CFamily with sequence similarity 110 member C. (320 aa)
RASSF1Ras association domain family member 1. (345 aa)
NUDCD2NudC domain-containing protein 2. (157 aa)
NUBP2Nucleotide binding protein 2. (407 aa)
KNSTRNKinetochore localized astrin (SPAG5) binding protein. (316 aa)
FAM193AFamily with sequence similarity 193 member A. (1519 aa)
ALMS1ALMS1 centrosome and basal body associated protein. (4380 aa)
PLK3Serine/threonine-protein kinase PLK. (664 aa)
YPEL5Protein yippee-like; Belongs to the yippee family. (121 aa)
EFCAB3EF-hand calcium binding domain 3. (488 aa)
UMODUromodulin. (641 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (397 aa)
KNTC1Kinetochore associated 1. (2209 aa)
AUNIPAurora kinase A and ninein interacting protein. (351 aa)
SMC3Structural maintenance of chromosomes protein. (1196 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
BCCIPBRCA2 and CDKN1A-interacting protein isoform BCCIPalpha. (323 aa)
CTDP1CTD phosphatase subunit 1. (1238 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
IKIK cytokine. (557 aa)
GPSM2G-protein-signaling modulator 2. (686 aa)
EFCAB13EF-hand calcium binding domain 13. (973 aa)
PKP4Plakophilin-4 isoform a. (1192 aa)
EML1EMAP like 1. (840 aa)
CETN1Centrin 1. (181 aa)
UNC119Protein unc-119 homolog A isoform a. (240 aa)
ABRAXAS2Abraxas 2, BRISC complex subunit. (423 aa)
CNTRLCentriolin. (2325 aa)
KIF20BKinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1822 aa)
EFHC1EF-hand domain-containing protein 1 isoform 1. (640 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
BOD1Biorientation of chromosomes in cell division protein 1 isoform a. (185 aa)
FAM161AFAM161 centrosomal protein A. (716 aa)
ALPK1Alpha kinase 1. (1245 aa)
CSPP1Centrosome and spindle pole associated protein 1. (1297 aa)
HSF1Heat shock transcription factor 1. (507 aa)
CCDC155Coiled-coil domain containing 155. (575 aa)
F6VV14_MACMUUncharacterized protein. (242 aa)
PSRC1Proline/serine-rich coiled-coil protein 1 isoform a. (332 aa)
DCTN1CAP-Gly domain-containing protein. (1433 aa)
CENPFCentromere protein F. (3113 aa)
NPM1Nucleophosmin isoform 1. (294 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (538 aa)
FBF1Fas binding factor 1. (1147 aa)
TUBGCP4Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (724 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
CALML5Calmodulin-like protein 5. (146 aa)
FAM110AFamily with sequence similarity 110 member A. (295 aa)
GIT1GIT ArfGAP 1. (794 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
ENSMMUP00000055202Uncharacterized protein. (203 aa)
FRYFRY microtubule binding protein. (3152 aa)
TUBGCP3Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (907 aa)
ENSMMUP00000053583HORMA domain-containing protein. (205 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (3048 aa)
HAUS1Coiled-coil domain-containing protein 5. (278 aa)
CDC14CCell division cycle 14C. (463 aa)
CEP95Centrosomal protein 95. (821 aa)
POC1APOC1 centriolar protein A. (407 aa)
STAG1Cohesin subunit SA-1. (1258 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (291 aa)
LOC717686Uncharacterized protein; Belongs to the calmodulin family. (105 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
DNAAF1Dynein assembly factor 1, axonemal. (708 aa)
CDC25BCell division cycle 25B. (570 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
SBDSUncharacterized protein. (226 aa)
PRC1Uncharacterized protein. (624 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (489 aa)
KLHL21Kelch like family member 21. (597 aa)
CDC20Cell division cycle protein 20 homolog. (499 aa)
DDX11DEAD/H-box helicase 11. (970 aa)
SPOUT1Uncharacterized protein. (353 aa)
ODF2Outer dense fiber of sperm tails 2. (824 aa)
GOLGA2Golgin A2. (1021 aa)
LOC713290Uncharacterized protein. (702 aa)
NDUFB6RING-type domain-containing protein. (1085 aa)
POC1BPOC1 centriolar protein homolog B isoform a. (478 aa)
SGO1Shugoshin 1. (554 aa)
AURKASerine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (403 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
CUL3Cullin-3; Belongs to the cullin family. (768 aa)
RASSF10Ras association domain family member 10. (508 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
CCNB1G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa)
RGS14Regulator of G protein signaling 14. (566 aa)
NUP62Nuclear pore glycoprotein p62. (521 aa)
ZW10Zw10 kinetochore protein. (778 aa)
KIF11Kinesin-like protein KIF11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1898 aa)
TUBGCP2Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (884 aa)
NEK7Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (381 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (514 aa)
WDR62Uncharacterized protein. (1523 aa)
LATS2Non-specific serine/threonine protein kinase. (1086 aa)
UXTUbiquitously expressed prefoldin like chaperone. (225 aa)
CEP89Centrosomal protein 89. (784 aa)
AAASAladin WD repeat nucleoporin. (547 aa)
ENSMMUP00000067677Nucleoplasmin domain-containing protein. (183 aa)
ANKRD53Ankyrin repeat domain 53. (529 aa)
CKAP5Cytoskeleton-associated protein 5 isoform a. (2032 aa)
NEK2Serine/threonine-protein kinase Nek2 isoform 1. (445 aa)
TUBGCP6Tubulin gamma complex associated protein 6. (1732 aa)
ENSMMUP00000048641Uncharacterized protein. (258 aa)
CEP44Centrosomal protein 44. (399 aa)
MAPRE1Microtubule-associated protein RP/EB family member 1. (268 aa)
RMDN2Regulator of microtubule dynamics 2. (588 aa)
ENSMMUP00000072883Nucleoplasmin domain-containing protein. (250 aa)
RMDN3Regulator of microtubule dynamics 3. (592 aa)
TOPBP1Uncharacterized protein. (1527 aa)
ASPMAbnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3476 aa)
RAE1Ribonucleic acid export 1. (420 aa)
PLEKHG6Pleckstrin homology and RhoGEF domain containing G6. (790 aa)
HAUS8HAUS augmin like complex subunit 8. (391 aa)
CEP85Centrosomal protein 85. (800 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
UBXN2BUBX domain-containing protein 2B. (331 aa)
WDR73WD repeat domain 73. (372 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
DLGAP5DLG associated protein 5. (850 aa)
MAPKBP1Mitogen-activated protein kinase binding protein 1. (1514 aa)
NEDD1NEDD1 gamma-tubulin ring complex targeting factor. (660 aa)
F7DC82_MACMUUncharacterized protein. (293 aa)
LOC114675405Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (691 aa)
DYNC1I1WD_REPEATS_REGION domain-containing protein. (645 aa)
CDC14BCell division cycle 14B. (498 aa)
SPAG5Sperm associated antigen 5. (1195 aa)
ENSMMUP00000073741Uncharacterized protein. (110 aa)
RALBP1RalA binding protein 1. (655 aa)
BEX4Brain expressed X-linked 4. (176 aa)
BIRC6Baculoviral IAP repeat containing 6. (4891 aa)
MTCL1Microtubule crosslinking factor 1. (2028 aa)
ENSMMUP00000074770Uncharacterized protein. (197 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (622 aa)
RAD21Double-strand-break repair protein rad21 homolog. (631 aa)
CEP19Centrosomal protein of 19 kDa. (167 aa)
TBCCD1TBCC domain-containing protein 1. (557 aa)
LOC114675592Uncharacterized protein. (233 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (194 aa)
MISP3Uncharacterized protein. (387 aa)
SBDS-2Uncharacterized protein. (250 aa)
TMEM201Transmembrane protein 201 isoform 1. (667 aa)
LOC114669849Uncharacterized protein. (467 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (385 aa)
NDE1NudE neurodevelopment protein 1. (346 aa)
TPX2TPX2 microtubule nucleation factor. (757 aa)
CEP104Centrosomal protein 104. (925 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (817 aa)
KATNBL1Katanin regulatory subunit B1 like 1. (304 aa)
LATS1Large tumor suppressor kinase 1. (1224 aa)
CEP128Centrosomal protein 128. (1125 aa)
NINNinein. (2163 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (655 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2154 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (12%) [HD]