STRINGSTRING
DSG2 DSG2 DSC2 DSC2 FKBP1B FKBP1B NR4A1 NR4A1 AKAP9 AKAP9 NKX2-5 NKX2-5 TMEM38A TMEM38A STRIT1 STRIT1 SH2B1 SH2B1 SLC8A3 SLC8A3 PIK3CG PIK3CG CASQ2 CASQ2 SMAD7 SMAD7 C11H12orf57 C11H12orf57 CASQ1 CASQ1 CLIC2 CLIC2 CHGA CHGA RGS2 RGS2 ASB3 ASB3 CAV3 CAV3 UCN UCN MYL2 MYL2 P2RX4 P2RX4 TRPV4 TRPV4 SLC9A1 SLC9A1 TRPM4 TRPM4 ADRA1A ADRA1A BIN1 BIN1 GRK2 GRK2 CAMK2D CAMK2D ATP1A1 ATP1A1 RNF207 RNF207 ASPH ASPH ANKRD66 ANKRD66 SUMO1 SUMO1 TNNI1 TNNI1 CCN2 CCN2 ATP2A2 ATP2A2 F6UJ19_MACMU F6UJ19_MACMU DLG1 DLG1 ACTN3 ACTN3 CTNNA3 CTNNA3 ANK2 ANK2 SRI SRI ANKRD44 ANKRD44 ACE2 ACE2 GATA4 GATA4 CALML5 CALML5 TNNT3 TNNT3 SCN10A SCN10A SCN5A SCN5A SCN4A SCN4A PKP2 PKP2 RYR2 RYR2 GJA5 GJA5 TMEM38B TMEM38B EHD3 EHD3 KBTBD13 KBTBD13 MYBPH MYBPH PDE5A PDE5A PDE4B PDE4B KCNQ1 KCNQ1 NPPA NPPA ANKRD28 ANKRD28 ZC3H12A ZC3H12A PDE4D PDE4D DMD DMD CACNA1C CACNA1C JUP JUP RANGRF RANGRF NOS1 NOS1 CAV1 CAV1 MYL3 MYL3 DSP DSP BMP10 BMP10 GSTO1 GSTO1 SLC8A1 SLC8A1 MYBPC3 MYBPC3 HRC HRC KCNJ2 KCNJ2 ADRA1B ADRA1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DSG2Desmoglein 2. (1115 aa)
DSC2Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (947 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (670 aa)
AKAP9A-kinase anchoring protein 9. (4049 aa)
NKX2-5NK2 homeobox 5. (324 aa)
TMEM38ATransmembrane protein 38A. (352 aa)
STRIT1Small transmembrane regulator of ion transport 1. (35 aa)
SH2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1087 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1102 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (446 aa)
SMAD7Mothers against decapentaplegic homolog. (462 aa)
C11H12orf57Protein C10. (126 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (398 aa)
CLIC2Chloride intracellular channel protein 2. (247 aa)
CHGAChromogranin A. (702 aa)
RGS2Regulator of G-protein signaling 2. (211 aa)
ASB3Uncharacterized protein. (557 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (196 aa)
UCNUrocortin. (124 aa)
MYL2Myosin light chain 2. (166 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (467 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (963 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1215 aa)
ADRA1AAdrenoceptor alpha 1A. (445 aa)
BIN1Bridging integrator 1. (668 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
CAMK2DProtein kinase domain-containing protein. (687 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
RNF207Ring finger protein 207. (634 aa)
ASPHAspartate beta-hydroxylase. (756 aa)
ANKRD66Ankyrin repeat domain 66. (250 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
TNNI1Uncharacterized protein. (187 aa)
CCN2Cellular communication network factor 2. (349 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1011 aa)
F6UJ19_MACMUUncharacterized protein; Belongs to the GST superfamily. (241 aa)
DLG1Disks large homolog 1 isoform 2; Belongs to the MAGUK family. (926 aa)
ACTN3Uncharacterized protein. (942 aa)
CTNNA3Catenin alpha-3. (895 aa)
ANK2Ankyrin 2. (4045 aa)
SRISorcin isoform a. (198 aa)
ANKRD44Ankyrin repeat domain 44. (1068 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
GATA4GATA binding protein 4. (443 aa)
CALML5Calmodulin-like protein 5. (146 aa)
TNNT3Troponin T3, fast skeletal type. (289 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1956 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
PKP2Plakophilin 2. (790 aa)
RYR2Ryanodine receptor 2. (4967 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
TMEM38BTrimeric intracellular cation channel type B. (291 aa)
EHD3EH domain-containing protein 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
KBTBD13BTB domain-containing protein. (458 aa)
MYBPHMyosin binding protein H. (477 aa)
PDE5APhosphodiesterase. (875 aa)
PDE4BPhosphodiesterase. (736 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
NPPANatriuretic peptide A. (153 aa)
ANKRD28Ankyrin repeat domain 28. (1083 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (601 aa)
PDE4DPhosphodiesterase. (809 aa)
DMDUncharacterized protein. (3685 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
JUPUncharacterized protein. (744 aa)
RANGRFUncharacterized protein. (186 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
CAV1Caveolin 1. (303 aa)
MYL3Myosin light chain 3. (254 aa)
DSPDesmoplakin. (2871 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
GSTO1Glutathione S-transferase omega-1 isoform 1. (241 aa)
SLC8A1J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
MYBPC3Myosin binding protein C, cardiac. (1274 aa)
HRCHistidine rich calcium binding protein. (799 aa)
KCNJ2Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be bl [...] (427 aa)
ADRA1BAdrenoceptor alpha 1B. (518 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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