STRINGSTRING
LOC718677 LOC718677 BMP10 BMP10 SMAD4 SMAD4 ACVR1 ACVR1 BMP6 BMP6 NODAL NODAL TGFB1 TGFB1 HFE HFE DAB2 DAB2 ACVRL1 ACVRL1 TGFBR1 TGFBR1 PYCR2 PYCR2 SDCBP SDCBP BMP8B BMP8B GDF2 GDF2 TGFB2 TGFB2 GDF6 GDF6 BMP15 BMP15 BMP2 BMP2 GDF5 GDF5 ACVR2A ACVR2A GDF3 GDF3 TWSG1 TWSG1 ENG ENG INHBA INHBA BMP4 BMP4 GDF7 GDF7 GDF11 GDF11 LOC699676 LOC699676 BMP7 BMP7 INHBC INHBC INHBB INHBB RBPMS RBPMS BMPR1A BMPR1A INHA INHA BMPR2 BMPR2 TGFBR2 TGFBR2 BMP3 BMP3 BMP5 BMP5 GDF10 GDF10 TGFB3 TGFB3 MSTN MSTN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC718677TGF_BETA_2 domain-containing protein. (402 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
BMP6Bone morphogenetic protein 6. (511 aa)
NODALNodal growth differentiation factor. (347 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
DAB2Differentially-expressed protein 2. (770 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
PYCR2Left-right determination factor. (364 aa)
SDCBPSyndecan binding protein. (324 aa)
BMP8BTGF_BETA_2 domain-containing protein. (402 aa)
GDF2Growth differentiation factor 2. (429 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
GDF6Growth differentiation factor 6. (455 aa)
BMP15TGF_BETA_2 domain-containing protein. (393 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
GDF5Growth differentiation factor 5. (499 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
GDF3Growth differentiation factor 3. (364 aa)
TWSG1Twisted gastrulation protein-like protein 1. (223 aa)
ENGEndoglin. (672 aa)
INHBAInhibin subunit beta A. (426 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
GDF7Growth differentiation factor 7. (539 aa)
GDF11Growth differentiation factor 11. (408 aa)
LOC699676Left-right determination factor. (366 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
INHBCTGF_BETA_2 domain-containing protein. (356 aa)
INHBBInhibin subunit beta B. (407 aa)
RBPMSRNA binding protein, mRNA processing factor. (224 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
MSTNGrowth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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