STRINGSTRING
SNX12 SNX12 CAST CAST SERPINF2 SERPINF2 BCL2L12 BCL2L12 FURIN FURIN GAS1 GAS1 CST7 CST7 THBS1 THBS1 SERPINE2 SERPINE2 CARD17 CARD17 TMEM98 TMEM98 CTSZ CTSZ LRRK2 LRRK2 IL1R2 IL1R2 CARD18 CARD18 NLRP7 NLRP7 GLG1 GLG1 CHAC1 CHAC1 SIRT4 SIRT4 SERPINE1 SERPINE1 NOL3 NOL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNX12PX domain-containing protein. (250 aa)
CASTCalpastatin. (789 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (594 aa)
BCL2L12BCL2 like 12. (250 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
GAS1Growth arrest specific 1. (372 aa)
CST7Cystatin-F. (145 aa)
THBS1Thrombospondin 1. (1170 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
CARD17Caspase recruitment domain family member 17. (110 aa)
TMEM98Transmembrane protein 98. (226 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (303 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
IL1R2Uncharacterized protein. (398 aa)
CARD18Caspase recruitment domain family member 18. (91 aa)
NLRP7Uncharacterized protein. (1009 aa)
GLG1Golgi glycoprotein 1. (1212 aa)
CHAC1Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (264 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (323 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (407 aa)
NOL3Nucleolar protein 3. (206 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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