Your Input: | |||||
TNFRSF1B | TNF receptor superfamily member 1B. (501 aa) | ||||
ASPA | Uncharacterized protein. (329 aa) | ||||
IL6ST | Uncharacterized protein. (942 aa) | ||||
KRAS | KRAS proto-oncogene, GTPase. (412 aa) | ||||
VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (421 aa) | ||||
DAG1 | Dystroglycan preproprotein. (894 aa) | ||||
TSPO | Translocator protein isoform PBR. (169 aa) | ||||
SERPINE2 | Serpin family E member 2; Belongs to the serpin family. (409 aa) | ||||
RNF112 | RING finger protein 112. (631 aa) | ||||
HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) | ||||
PTPRZ1 | Uncharacterized protein. (2319 aa) | ||||
UFL1 | E3 UFM1-protein ligase 1. (793 aa) | ||||
PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) | ||||
PRPF19 | Pre-mRNA processing factor 19. (512 aa) | ||||
TTBK1 | Tau tubulin kinase 1. (1433 aa) | ||||
TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (660 aa) | ||||
NOTCH1 | Notch receptor 1. (2556 aa) | ||||
OLIG2 | Oligodendrocyte transcription factor 2. (323 aa) | ||||
NKX6-1 | NK6 homeobox 1. (366 aa) | ||||
GJC2 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (441 aa) | ||||
E2F1 | E2F transcription factor 1. (437 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
SYNJ1 | Synaptojanin 1. (1614 aa) | ||||
GFAP | Glial fibrillary acidic protein; Belongs to the intermediate filament family. (462 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (266 aa) | ||||
LYN | Tyrosine-protein kinase. (577 aa) | ||||
LIF | LIF interleukin 6 family cytokine. (206 aa) | ||||
ACY3 | Aspartoacylase-2. (319 aa) | ||||
BIN1 | Bridging integrator 1. (668 aa) | ||||
MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
GSX2 | GS homeobox 2. (304 aa) | ||||
HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) | ||||
MDK | Midkine. (143 aa) | ||||
SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa) | ||||
RHEB | Uncharacterized protein. (249 aa) | ||||
SOX10 | SRY-box transcription factor 10. (467 aa) | ||||
IL34 | Uncharacterized protein. (364 aa) | ||||
BMP2 | Bone morphogenetic protein 2. (396 aa) | ||||
NKX6-2 | Homeobox protein Nkx-6.2. (277 aa) | ||||
NKX2-2 | Homeobox domain-containing protein. (451 aa) | ||||
NTN1 | Netrin 1. (604 aa) | ||||
PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa) | ||||
SOX8 | SRY-box transcription factor 8. (617 aa) | ||||
TENM4 | Teneurin transmembrane protein 4. (2929 aa) | ||||
DICER1 | Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (2011 aa) | ||||
PLAG1 | Pleiomorphic adenoma gene 1 protein. (500 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa) | ||||
SLC7A5 | Large neutral amino acids transporter small subunit 1. (507 aa) | ||||
SPINT1 | Serine peptidase inhibitor, Kunitz type 1. (667 aa) | ||||
LRP2 | LDL receptor related protein 2. (4660 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) | ||||
PTN | Uncharacterized protein. (172 aa) | ||||
EGR2 | Uncharacterized protein. (489 aa) |