STRINGSTRING
DLX3 DLX3 AXIN1 AXIN1 TNKS TNKS DACT1 DACT1 WNT5B WNT5B PRICKLE2 PRICKLE2 FZD8 FZD8 LEO1 LEO1 WNT16 WNT16 PKD1 PKD1 BRD7 BRD7 YAP1 YAP1 GPC4 GPC4 FZD4 FZD4 KREMEN2 KREMEN2 AMER1 AMER1 GRHL3 GRHL3 ROR1 ROR1 WNT3A WNT3A CSNK1A1L CSNK1A1L CSNK2B CSNK2B PLCG2 PLCG2 PAF1 PAF1 SLC9A3R1 SLC9A3R1 CPZ CPZ DVL3 DVL3 PYGO2 PYGO2 WNT8B WNT8B CSNK1G2 CSNK1G2 CSNK1G3 CSNK1G3 CCNY CCNY FZD10 FZD10 GATA3 GATA3 TNKS2 TNKS2 WNT2B WNT2B BARX1 BARX1 USP34 USP34 TMEM88 TMEM88 RSPO1 RSPO1 PTEN PTEN EXT1 EXT1 PKD2 PKD2 VANGL1 VANGL1 TRIM2 TRIM2 LDB1 LDB1 CALCOCO1 CALCOCO1 FGF9 FGF9 PRKAA2 PRKAA2 CTDNEP1 CTDNEP1 DKK1 DKK1 LRRC45 LRRC45 RAC3 RAC3 FZD2 FZD2 ZBTB33 ZBTB33 SIAH1 SIAH1 NXN NXN CTR9 CTR9 HHEX HHEX CYLD CYLD UBAC2 UBAC2 RARG RARG LMBR1L LMBR1L RNF138 RNF138 SENP2 SENP2 JUP JUP DISC1 DISC1 STK4 STK4 TMEM198 TMEM198 MCC MCC MYOC MYOC LGR6 LGR6 CAV1 CAV1 ARHGEF19 ARHGEF19 CELSR3 CELSR3 RSPO3 RSPO3 CELSR2 CELSR2 HBP1 HBP1 RTF1 RTF1 SIAH2 SIAH2 WNT1 WNT1 SFRP2 SFRP2 LRRK2 LRRK2 CSNK2A2 CSNK2A2 BCL9 BCL9 SOSTDC1 SOSTDC1 WIF1 WIF1 PPP1CA PPP1CA IFT80 IFT80 CBY1 CBY1 EDA EDA WNT7A WNT7A MARK4 MARK4 NLK NLK ETV2 ETV2 LATS2 LATS2 CTHRC1 CTHRC1 NKD2 NKD2 FRAT2 FRAT2 AMFR AMFR TCF7L1 TCF7L1 VANGL2 VANGL2 CCNE1 CCNE1 DKK4 DKK4 WNT3 WNT3 AMER2 AMER2 CELSR1 CELSR1 DAAM1 DAAM1 RAC1 RAC1 SFRP4 SFRP4 CSNK1G1 CSNK1G1 ZBED3 ZBED3 KREMEN1 KREMEN1 ZRANB1 ZRANB1 TNIK TNIK MARK1 MARK1 LRRFIP2 LRRFIP2 TCF7L2 TCF7L2 DKK3 DKK3 WNT8A WNT8A CELA1 CELA1 LOC706619 LOC706619 CTNND2 CTNND2 SCYL2 SCYL2 FRAT1 FRAT1 TTC33 TTC33 CCN4 CCN4 FZD6 FZD6 SFRP1 SFRP1 WWOX WWOX CDH3 CDH3 CHD8 CHD8 PTK7 PTK7 TCF7 TCF7 EDNRA EDNRA RNF43 RNF43 DAB2 DAB2 FOXO1 FOXO1 TRABD2A TRABD2A STRN STRN LGR4 LGR4 LRP4 LRP4 CTNND1 CTNND1 MARK2 MARK2 CUL3 CUL3 RSPO4 RSPO4 LRP5 LRP5 ROR2 ROR2 PRICKLE1 PRICKLE1 MBD2 MBD2 FZD7 FZD7 FERMT2 FERMT2 TLE1 TLE1 DACT3 DACT3 CCDC90B CCDC90B DDX3X DDX3X TLE3 TLE3 LEF1 LEF1 STK3 STK3 WLS WLS DVL1 DVL1 FZD9 FZD9 WDR61 WDR61 TGFB1I1 TGFB1I1 MED12 MED12 DIXDC1 DIXDC1 FBXW11 FBXW11 BTRC BTRC EDNRB EDNRB KLHL12 KLHL12 C12orf43 C12orf43 MAGI2 MAGI2 FGF10 FGF10 FOXD1 FOXD1 HESX1 HESX1 APC2 APC2 BCL9L BCL9L NDRG2 NDRG2 MITF MITF TRABD2B TRABD2B TIAM1 TIAM1 WNT10B WNT10B ENSMMUP00000059946 ENSMMUP00000059946 CCDC88A CCDC88A GSK3B GSK3B RYK RYK DDX3Y DDX3Y DVL2 DVL2 MESD MESD ENSMMUP00000062204 ENSMMUP00000062204 LZTS2 LZTS2 EDN1 EDN1 WNT11 WNT11 WNT2 WNT2 LOC707807 LOC707807 CTNNB1 CTNNB1 SFRP5 SFRP5 FAM53B FAM53B ENSMMUP00000063403 ENSMMUP00000063403 SDC1 SDC1 DAAM2 DAAM2 PIAS4 PIAS4 ISL1 ISL1 NKD1 NKD1 HMGXB4 HMGXB4 LRP6 LRP6 WNT6 WNT6 EPM2A EPM2A SHH SHH FZD3 FZD3 VAX2 VAX2 BMP2 BMP2 SOX17 SOX17 MACF1 MACF1 PORCN PORCN WNT4 WNT4 AMOTL2 AMOTL2 TMEM170B TMEM170B SMURF1 SMURF1 DKK2 DKK2 WNT10A WNT10A DDB1 DDB1 APC APC RECK RECK DDIT3 DDIT3 CDK14 CDK14 WNT9B WNT9B CSNK1D CSNK1D CXXC4 CXXC4 SOST SOST RSPO2 RSPO2 APCDD1 APCDD1 NDP NDP NOTUM NOTUM GRK5 GRK5 ADGRA2 ADGRA2 AMOTL1 AMOTL1 ENSMMUP00000072696 ENSMMUP00000072696 CDC73 CDC73 INVS INVS GSC GSC PYGO1 PYGO1 GRK6 GRK6 DRAXIN DRAXIN CSNK1E CSNK1E FRZB FRZB WNT5A WNT5A OTULIN OTULIN TAX1BP3 TAX1BP3 MYLK3 MYLK3 WNT7B WNT7B SMURF2 SMURF2 CCAR2 CCAR2 AXIN2 AXIN2 PLPP3 PLPP3 KLF4 KLF4 TLE2 TLE2 FBXW4 FBXW4 WNT9A WNT9A GID8 GID8 CSNK1A1 CSNK1A1 CCDC88C CCDC88C FZD5 FZD5 BCL7B BCL7B SHISA6 SHISA6 LOC114672614 LOC114672614 CCND1 CCND1 HIC1 HIC1 CPE CPE RNF146 RNF146
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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DLX3Distal-less homeobox 3. (287 aa)
AXIN1Axin 1. (867 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PRICKLE2Prickle-like protein 2. (844 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (693 aa)
LEO1RNA polymerase-associated protein LEO1. (666 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4298 aa)
BRD7Bromodomain containing 7. (651 aa)
YAP1Yes associated protein 1. (508 aa)
GPC4Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
FZD4Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (462 aa)
AMER1APC membrane recruitment protein 1. (1136 aa)
GRHL3Grainyhead like transcription factor 3. (626 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
CSNK1A1LCasein kinase I isoform alpha-like protein; Belongs to the protein kinase superfamily. (337 aa)
CSNK2BChimera Csnk2b-Ly6g5b splicing isoform 992. (298 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
SLC9A3R1SLC9A3 regulator 1. (387 aa)
CPZCarboxypeptidase Z. (652 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3. (716 aa)
PYGO2Pygopus family PHD finger 2. (405 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
CSNK1G2Casein kinase 1 gamma 2. (535 aa)
CSNK1G3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (455 aa)
CCNYCYCLIN domain-containing protein; Belongs to the cyclin family. (350 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
GATA3GATA binding protein 3. (444 aa)
TNKS2Poly [ADP-ribose] polymerase. (1258 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa)
BARX1BARX homeobox 1. (254 aa)
USP34Ubiquitin carboxyl-terminal hydrolase 34; Belongs to the peptidase C19 family. (3546 aa)
TMEM88Transmembrane protein 88. (159 aa)
RSPO1R-spondin 1. (437 aa)
PTENUncharacterized protein. (589 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (969 aa)
VANGL1Vang-like protein. (535 aa)
TRIM2Transmembrane 131 like. (1724 aa)
LDB1LIM domain-binding protein 1 isoform 1. (411 aa)
CALCOCO1Calcium binding and coiled-coil domain 1. (714 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (387 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
ZBTB33Transcriptional regulator Kaiso. (672 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
NXNNucleoredoxin. (435 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
UBAC2UBA domain-containing protein. (426 aa)
RARGRetinoic acid receptor gamma. (454 aa)
LMBR1LUncharacterized protein; Belongs to the LIMR family. (489 aa)
RNF138Ring finger protein 138. (245 aa)
SENP2SUMO specific peptidase 2. (663 aa)
JUPUncharacterized protein. (744 aa)
DISC1Uncharacterized protein. (885 aa)
STK4Serine/threonine-protein kinase 4 18kDa subunit; Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regul [...] (487 aa)
TMEM198Transmembrane protein 198. (360 aa)
MCCMCC regulator of WNT signaling pathway. (1014 aa)
MYOCMyocilin. (491 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (966 aa)
CAV1Caveolin 1. (303 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19. (809 aa)
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3312 aa)
RSPO3R-spondin 3. (273 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2926 aa)
HBP1HMG-box transcription factor 1. (618 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (711 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
SFRP2Secreted frizzled-related protein 2. (295 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa)
BCL9B-cell CLL/lymphoma 9 protein. (1426 aa)
SOSTDC1Sclerostin domain containing 1. (206 aa)
WIF1WNT inhibitory factor 1. (445 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (347 aa)
IFT80Intraflagellar transport protein 80 homolog isoform a. (777 aa)
CBY1Chibby family member 1, beta catenin antagonist. (268 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
MARK4Non-specific serine/threonine protein kinase. (752 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
ETV2ETS variant 2. (342 aa)
LATS2Non-specific serine/threonine protein kinase. (1086 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (477 aa)
FRAT2FRAT regulator of WNT signaling pathway 2. (233 aa)
AMFRAutocrine motility factor receptor. (643 aa)
TCF7L1Transcription factor 7 like 1. (589 aa)
VANGL2Vang-like protein. (521 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
AMER2APC membrane recruitment protein 2. (550 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (1818 aa)
DAAM1Disheveled-associated activator of morphogenesis 1. (1078 aa)
RAC1Uncharacterized protein. (212 aa)
SFRP4Secreted frizzled-related protein 4; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium- dependent phosphate uptake. (346 aa)
CSNK1G1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (475 aa)
ZBED3BED-type domain-containing protein. (231 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (492 aa)
ZRANB1Zinc finger RANBP2-type containing 1. (734 aa)
TNIKTRAF2 and NCK interacting kinase. (1311 aa)
MARK1Non-specific serine/threonine protein kinase. (795 aa)
LRRFIP2LRR binding FLII interacting protein 2. (721 aa)
TCF7L2Transcription factor 7 like 2. (632 aa)
DKK3Dickkopf-related protein 3. (350 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
CELA1Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (258 aa)
LOC706619Uncharacterized protein. (805 aa)
CTNND2Catenin delta 2. (1251 aa)
SCYL2SCY1-like protein 2. (929 aa)
FRAT1FRAT regulator of WNT signaling pathway 1. (279 aa)
TTC33Non-specific serine/threonine protein kinase. (581 aa)
CCN4WNT1-inducible-signaling pathway protein 1. (367 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
WWOXWW domain containing oxidoreductase. (414 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (829 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2581 aa)
PTK7Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
TCF7Transcription factor 7. (571 aa)
EDNRAUncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (427 aa)
RNF43RING-type domain-containing protein. (783 aa)
DAB2Differentially-expressed protein 2. (770 aa)
FOXO1Forkhead box O1. (655 aa)
TRABD2ATraB domain containing 2A. (505 aa)
STRNStriatin. (813 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (951 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1905 aa)
CTNND1Uncharacterized protein. (968 aa)
MARK2Non-specific serine/threonine protein kinase. (788 aa)
CUL3Cullin-3; Belongs to the cullin family. (768 aa)
RSPO4R-spondin 4. (234 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1612 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (942 aa)
PRICKLE1Prickle planar cell polarity protein 1. (848 aa)
MBD2Methyl-CpG binding domain protein 2. (412 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (597 aa)
FERMT2PH domain-containing protein. (698 aa)
TLE1TLE family member 1, transcriptional corepressor. (804 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (631 aa)
CCDC90BCoiled-coil domain containing 90B. (305 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform 1; Belongs to the DEAD box helicase family. (662 aa)
TLE3TLE family member 3, transcriptional corepressor. (901 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
STK3Uncharacterized protein. (519 aa)
WLSProtein wntless homolog isoform 2. (545 aa)
DVL1Dishevelled segment polarity protein 1. (695 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
WDR61WD repeat domain 61. (359 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (485 aa)
MED12Mediator complex subunit 12. (2178 aa)
DIXDC1DIX domain containing 1. (683 aa)
FBXW11Uncharacterized protein. (563 aa)
BTRCUncharacterized protein. (629 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (527 aa)
KLHL12BTB domain-containing protein. (606 aa)
C12orf43Chromosome 12 open reading frame 43. (298 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1452 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FOXD1Forkhead box D1. (468 aa)
HESX1HESX homeobox 1. (185 aa)
APC2APC regulator of WNT signaling pathway 2. (2403 aa)
BCL9LBCL9 like. (1500 aa)
NDRG2NDRG family member 2. (407 aa)
MITFMicrophthalmia-associated transcription factor isoform 1. (520 aa)
TRABD2BTraB domain containing 2B. (517 aa)
TIAM1Uncharacterized protein. (1591 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
ENSMMUP00000059946Protein kinase domain-containing protein. (224 aa)
CCDC88ACoiled-coil domain containing 88A. (1999 aa)
GSK3BGlycogen synthase kinase-3 beta isoform 1; Belongs to the protein kinase superfamily. (433 aa)
RYKReceptor like tyrosine kinase. (611 aa)
DDX3YATP-dependent RNA helicase DDX3Y; Belongs to the DEAD box helicase family. (659 aa)
DVL2Dishevelled segment polarity protein 2. (767 aa)
MESDMesoderm development LRP chaperone. (234 aa)
ENSMMUP00000062204Uncharacterized protein. (81 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa)
EDN1Preproendothelin-1. (211 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
LOC707807DUF4203 domain-containing protein. (178 aa)
CTNNB1Catenin beta-1. (781 aa)
SFRP5Secreted frizzled related protein 5. (449 aa)
FAM53BUncharacterized protein. (422 aa)
ENSMMUP00000063403Uncharacterized protein. (81 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (505 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1077 aa)
PIAS4Protein inhibitor of activated STAT 4. (561 aa)
ISL1ISL LIM homeobox 1. (413 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (499 aa)
HMGXB4HMG-box containing 4. (644 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
VAX2Ventral anterior homeobox 2. (290 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
SOX17SRY-box transcription factor 17. (414 aa)
MACF1Microtubule actin crosslinking factor 1. (5611 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (570 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
AMOTL2Angiomotin like 2. (839 aa)
TMEM170BTransmembrane protein 170B. (132 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
DKK2Uncharacterized protein. (259 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
APCAPC regulator of WNT signaling pathway. (2871 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (962 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa)
CDK14Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
CSNK1DProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (427 aa)
CXXC4CXXC finger protein 4. (372 aa)
SOSTSclerostin. (213 aa)
RSPO2Uncharacterized protein. (243 aa)
APCDD1Adenomatosis polyposis down-regulated 1 protein. (514 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (670 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
ADGRA2Adhesion G protein-coupled receptor A2. (1348 aa)
AMOTL1Angiomotin like 1. (986 aa)
ENSMMUP00000072696Uncharacterized protein. (103 aa)
CDC73Parafibromin. (531 aa)
INVSInversin. (1064 aa)
GSCGoosecoid homeobox. (259 aa)
PYGO1Pygopus family PHD finger 1. (419 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (560 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
CSNK1EProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (462 aa)
OTULINUncharacterized protein. (352 aa)
TAX1BP3Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. (124 aa)
MYLK3VPS35 retromer complex component. (1442 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
CCAR2P30 DBC protein. (920 aa)
AXIN2Axin 2. (862 aa)
PLPP3acidPPc domain-containing protein. (353 aa)
KLF4Kruppel like factor 4. (544 aa)
TLE2TLE family member 2, transcriptional corepressor. (844 aa)
FBXW4F-box and WD repeat domain containing 4. (591 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa)
GID8Protein C20orf11. (228 aa)
CSNK1A1Casein kinase I isoform alpha isoform 1; Belongs to the protein kinase superfamily. (365 aa)
CCDC88CCoiled-coil domain containing 88C. (2028 aa)
FZD5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
BCL7BUncharacterized protein. (251 aa)
SHISA6Shisa family member 6. (553 aa)
LOC114672614Uncharacterized protein. (137 aa)
CCND1Uncharacterized protein; Belongs to the cyclin family. (303 aa)
HIC1HIC ZBTB transcriptional repressor 1. (828 aa)
CPECarboxypeptidase E preproprotein. (476 aa)
RNF146E3 ubiquitin-protein ligase RNF146 isoform b. (360 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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