STRINGSTRING
LRRK2 LRRK2 TNKS TNKS HIPK2 HIPK2 VRK1 VRK1 CDC42BPG CDC42BPG MAPK8 MAPK8 WNK3 WNK3 TAF1 TAF1 MAP3K12 MAP3K12 UMOD UMOD TBK1 TBK1 CDK5R1 CDK5R1 TGFBR2 TGFBR2 F7B371_MACMU F7B371_MACMU PDPK1 PDPK1 TSSK4 TSSK4 MAPK1 MAPK1 PRKDC PRKDC LMTK2 LMTK2 TTBK1 TTBK1 CSNK2A2 CSNK2A2 PRKD2 PRKD2 DYRK1A DYRK1A ACVR1 ACVR1 WNK1 WNK1 NLK NLK CIT CIT CDK5 CDK5 DYRK4 DYRK4 STK11 STK11 PRKD1 PRKD1 DYRK1B DYRK1B MAP3K10 MAP3K10 CDK1 CDK1 CHEK1 CHEK1 ROCK2 ROCK2 MARK2 MARK2 CSNK2A1 CSNK2A1 CLK1 CLK1 HIPK1 HIPK1 TAF1L TAF1L MAPK10 MAPK10 ROCK1 ROCK1 ATF2 ATF2 CAD CAD TGFBR1 TGFBR1 ACVR1B ACVR1B CAMK2D CAMK2D GRK2 GRK2 DCAF1 DCAF1 OXSR1 OXSR1 PKN1 PKN1 GSK3B GSK3B AKT1 AKT1 PRKCB PRKCB MYLK2 MYLK2 HIPK3 HIPK3 DYRK2 DYRK2 CAMK2A CAMK2A BCL2 BCL2 PRKCA PRKCA CDC42BPA CDC42BPA MTOR MTOR PRKCD PRKCD SBK1 SBK1 HASPIN HASPIN ULK1 ULK1 STK39 STK39 CDC42BPB CDC42BPB CDK10 CDK10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRK2Leucine rich repeat kinase 2. (2527 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
HIPK2Homeodomain interacting protein kinase 2. (1212 aa)
VRK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
CDC42BPGCDC42 binding protein kinase gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1552 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
WNK3WNK lysine deficient protein kinase 3. (1787 aa)
TAF1Transcription initiation factor TFIID subunit. (1895 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (937 aa)
UMODUromodulin. (641 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
F7B371_MACMUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (313 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (557 aa)
TSSK4Testis specific serine kinase 4. (338 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa)
LMTK2Lemur tyrosine kinase 2. (1501 aa)
TTBK1Tau tubulin kinase 1. (1433 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
WNK1WNK lysine deficient protein kinase 1. (2844 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
CITCitron rho-interacting serine/threonine kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2132 aa)
CDK5Cyclin dependent kinase 5. (364 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (635 aa)
STK11Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (433 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (640 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (952 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
CHEK1STT3 oligosaccharyltransferase complex catalytic subunit A. (768 aa)
ROCK2Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
MARK2Non-specific serine/threonine protein kinase. (788 aa)
CSNK2A1Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily. (391 aa)
CLK1CDC like kinase 1. (596 aa)
HIPK1Uncharacterized protein. (1598 aa)
TAF1LTATA-box binding protein associated factor 1 like. (1776 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2306 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
CAMK2DProtein kinase domain-containing protein. (687 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1576 aa)
OXSR1Serine/threonine-protein kinase OSR1. (527 aa)
PKN1Protein kinase N1. (1013 aa)
GSK3BGlycogen synthase kinase-3 beta isoform 1; Belongs to the protein kinase superfamily. (433 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
MYLK2Myosin light chain kinase 2. (603 aa)
HIPK3Homeodomain-interacting protein kinase 3 isoform 1. (1215 aa)
DYRK2Dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform 2. (601 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (622 aa)
BCL2BCL2 apoptosis regulator. (241 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1845 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa)
PRKCDProtein kinase C. (729 aa)
SBK1SH3 domain binding kinase 1. (491 aa)
HASPINHistone H3 associated protein kinase. (800 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
STK39Serine/threonine kinase 39. (550 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1728 aa)
CDK10Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (385 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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